Cynthia SC
@cynthiasc.bsky.social
260 followers 110 following 10 posts
I am fascinated by science, it inspires me and keeps me very motivated. 🧠 Staff Scientist at Lieber Institute for Brain Development | 🎓 Master in Computer Sciences | 🎓 Doctorate in Biological Sciences I Advanced analysis on multiomics and Visium ST
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cynthiasc.bsky.social
🔬 Diving into ATAC-seq workflows?
You've likely heard about Seurat, Signac, MACS2, Cicero, and chromVAR—core components in many workflows.
Here’s a quick overview I put together that showcases different approaches used across recent studies.
youtu.be/R5P8mGMXuIg?...
#SingleCell #Epigenomics #LIBD
[2025-05-21] Journal club on brain multiome papers
YouTube video by Leonardo Collado Torres
youtu.be
cynthiasc.bsky.social
¡Hola! 👋 Avances en nuestra investigación sobre la habenula humana, clave en motivación y estrés.
Usamos single-cell, epigenomics y spatial data para estudiarla.
Presentado en el 2025 Epigenomics Sciences Symposium (JHU). 🧠✨
#SingleCell #Epigenomics #LIBD
Poster-Session-Epigenomics-Sciences-Cluster
cynthiasc.bsky.social
👉 Sharing a talk of the molecular neuroanatomical map of the human prefrontal cortex. This study integrates Visium Spatial data with snRNA-seq to map cell types and interactions across spatial domains. Le
Watch here: youtu.be/EhP5-mhw29w
Slides on video
Explore: research.libd.org/spatialDLPFC/
spatialDLPFC
research.libd.org
cynthiasc.bsky.social
🚀 Interested in multimodal analysis with WNN in Seurat?
Check out my recent RStatClub presentation, where we dive into Jaccard, canonical gene expression, and Silhouette for clustering evaluation!
📺 Watch here: speakerdeck.com/cyntsc/clust...
📑 Slides: www.youtube.com/watch?v=mE77...
#RStats
Clustering methods in multiome scRNA-seq and scATAC-seq
Main topics covered on this talk: Introducing the Weighted-Nearest Neighbor (WNN) for multimodal analysis A glance of WNN clustering algorithms availa…
speakerdeck.com
cynthiasc.bsky.social
🚀 Sharing insights on ArchR, a powerful tool for single-cell chromatin accessibility analysis! 🎯 ArchR excels in large datasets and integrates scATACseq with scRNAseq for cutting-edge multi-modal studies.
🎥 Dive deeper with the video: youtu.be/XNZx5Dlp6jY?...
#Bioinformatics #10xGenomics #LIBD
[2024-12-11] ArchR journal club
YouTube video by Leonardo Collado Torres
youtu.be
cynthiasc.bsky.social
#LIBD #SingleCellAnalysis #RNASeq #Bioinformatics #SpatialData
cynthiasc.bsky.social
📊 Extraído de la presentación de @mbarse.bsky.social en nuestro Journal Club, abajo se resumen métricas compartidas y diferentes de Space Ranger para datos Visium 10x standard y Visium 10x Cytassist. Interesados en el análisis espacial y plataformas Visium?
🔗 Más: speakerdeck.com/manishabarse...
cynthiasc.bsky.social
✨ Comparto desde nuestro `Journal Club` esta presentacion donde exploro `Feature selection and dimension reduction for single-cell RNAseq`. Si te interesa cómo aplicar modelos multinomiales en scRNAseq, ¡dale un vistazo! 🎥
🔗 Video: [GLM-PCA en acción](www.youtube.com/watch?v=8cyf...)
#LIBD #RNASeq
[2024-08-09] GLM-PCA overview
YouTube video by Leonardo Collado Torres
www.youtube.com
cynthiasc.bsky.social
Hi ! I am new here and I like to present my interests with this video from our Journal Club! This is an overview of the multiome analysis for scATACseq and scRNAseq using several
#CellRanger pipelines. This is inspired by our work at #LIBD and resources from 10x Genomics. youtu.be/fHVLi9-sftM?...
[2024-10-11] An overview of the CellRanger-ARC Pipeline Analysis
YouTube video by Leonardo Collado Torres
youtu.be