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danfengc.bsky.social
Danfeng Chen
@danfengc.bsky.social
11 followers 15 following 2 posts
PhD candidate in Storey Lab @Princeton University | Statistical genetics
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danfengc.bsky.social
Danfeng Chen @danfengc.bsky.social · Jan 6
Highlights
a) A distribution-free framework accounting for complex relationships among admixed populations.
b) Admixture-based estimation of individual-level pairwise coancestry at a resolution of kinship.
c) A tractable algorithm to form samples of genotypes from the estimated evolutionary process.
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Reposted by Danfeng Chen
yushifelixtang.bsky.social
Yushi Tang @yushifelixtang.bsky.social · Dec 12
Delighted to introduce our work on causal inference for genotype-phenotype analyses, with some thoughts about randomization in genetics www.biorxiv.org/content/10.1...
Identifying causal genotype-phenotype relationships for population-sampled parent-child trios
The process by which genes are transmitted from parent to child provides a source of randomization preceding all other factors that may causally influence any particular child phenotype. Because of th...
www.biorxiv.org
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danfengc.bsky.social
Danfeng Chen @danfengc.bsky.social · Jan 6
Happy to share "super admixture", a new framework for modeling the human population structure!
www.biorxiv.org/content/10.1...
Coancestry superposed on admixed populations yields measures of relatedness at individual-level resolution
The admixture model is widely applied to estimate and interpret population structure among individuals. Here we consider a "standard admixture" model that assumes the admixed populations are unrelated...
www.biorxiv.org
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