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Reposted by Paul Young

Critical Care Reviews @criticalcarereviews.com · 12h

The 8th & final trial for CCR Down Under is ECMO Rehab

➡️100-patient RCT testing early mobilisation during ECMO to reduce 6-month disability
➡️Will mobilisation improve outcomes?

Join us in Melbourne, December 9/10
criticalcarereviews.com/meetings/ccr...

CCR Down Under 2025

Critical Care Reviews Meeting Down Under - The Edge, Federation Square, Melbourne, December 9th - 10th, 2025

criticalcarereviews.com

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Paul Young @dogicuma.bsky.social · 1d

The September issue of Critical Care and Resuscitation is now online. An entire issue dedicated to the extraordinary legacy of Rinaldo Bellomo:
www.sciencedirect.com/journal/crit...

Critical Care and Resuscitation | A special issue of Critical Care and Resuscitation dedicated to Professor Rinaldo Bellomo | ScienceDirect.com by Elsevier

Read the latest articles of Critical Care and Resuscitation at ScienceDirect.com, Elsevier’s leading platform of peer-reviewed scholarly literature

www.sciencedirect.com

Paul Young @dogicuma.bsky.social · 2d

Once again, the emperor of inductive physiological reasoning is revealed to have no clothes...

Critical Care Reviews @criticalcarereviews.com · 2d

In >1,100 high-risk surgical patients, individualized periop BP targets based on pre-op nocturnal MAP were not associated with ↓ kidney or cardiac injury vs routine MAP ≥65 mm Hg

CCR Journal Watch – tracking the critical care literature daily
criticalcarereviews.com/latest-evide...

Paul Young @dogicuma.bsky.social · 3d

#MegaROXtrial 900 patients to go until 40000

Paul Young @dogicuma.bsky.social · 5d

Wow 60 patients enrolled in the #MegaROXtrial in less than 1 day. Only 940 to go.

Paul Young @dogicuma.bsky.social · 6d

39000th #MegaROXtrial patient enrolled in Nepal

Paul Young @dogicuma.bsky.social · 6d

The #MegaROXtrial has 1001 patients to go (& 38,999 enrolled)

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Paul Young @dogicuma.bsky.social · 6d

What a trial!
jamanetwork.com/journals/jam...

Respiratory Gas Shifts to Delay Asphyxiation in Critical Avalanche Burial

This randomized clinical trial examines the efficacy of a novel, user-carried avalanche safety device that delivers airflow from avalanche debris without requiring supplemental oxygen or a mouthpiece.

jamanetwork.com

Paul Young @dogicuma.bsky.social · 9d

The #MegaROXtrial has just 1100 patients to enrol.

Paul Young @dogicuma.bsky.social · 13d

#MegaROXtrial has 1200 left to recruit

Paul Young @dogicuma.bsky.social · 17d

#MegaROXtrial 1300 to go

Paul Young @dogicuma.bsky.social · 19d

#MegaROXtrial 1350 to go.

Paul Young @dogicuma.bsky.social · 21d

#MegaROXtrial 1400 to go.

Paul Young @dogicuma.bsky.social · 24d

Looks like 45 more days until we reach 40,000 patients recruited into the #MegaROXtrial

Reposted by Paul Young

Critical Care Reviews @criticalcarereviews.com · Sep 11

Latest trial announcement - CLIP II

Cryopreserved platelets vs liquid platelets for the management of post operative bleeding in patients undergoing cardiac surgery.

To be presented by Michael Reade

Join us in Melbourne - criticalcarereviews.com/meetings/ccr...

CCR Down Under 2025

Critical Care Reviews Meeting Down Under - The Edge, Federation Square, Melbourne, December 9th - 10th, 2025

criticalcarereviews.com

1

Paul Young @dogicuma.bsky.social · 24d

#MegaROXtrial 1500 to go.

Paul Young @dogicuma.bsky.social · 27d

This new analysis of the #PATCHtrial provides food for thought I think. Great work by @fgzamp.bsky.social
www.sciencedirect.com/science/arti...

Impact of different preferred functional outcomes on the results of the pre-hospital antifibrinolytics for traumatic coagulopathy and hemorrhage (PATCH-trauma) trial

Ordinal endpoints offer more detailed outcome assessment than mortality, though some disabilities may be considered worse than death by patients.To ev…

www.sciencedirect.com

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Paul Young @dogicuma.bsky.social · 28d

##MegaROXtrial 1600 to go

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Paul Young @dogicuma.bsky.social · Sep 13

#MegaROXtrial 1700 to go.

Paul Young @dogicuma.bsky.social · Sep 10

#MegaROXtrial 1800 to go

Paul Young @dogicuma.bsky.social · Sep 7

#MegaROXtrial 1900 to go.

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Paul Young @dogicuma.bsky.social · Sep 3

The #MegaROXtrial has 38006 participants enrolled. 38k was reached at 26 minutes past midnight local time when a patient was enrolled at QEII hospital in Australia

Paul Young @dogicuma.bsky.social · Sep 2

The #MegaROXtrial has 37959 patients. 38K the day after tomorrow I'd say.

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Paul Young @dogicuma.bsky.social · Aug 28

The #MegaROXtrial has reached 37851 enrolments. 38k likely next week and 40k on the cards for Nov.

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Paul Young @dogicuma.bsky.social · Aug 17

#MegaROXtrial 2.5K to go

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