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Reposted by Genoa Instruments | Microscopy

VicidominiLab @vicidominilab.bsky.social · 5d

Andrea Bucci and Laurent Le will run two workshops on building a custom #PhotonResolvedMicroscopy system and generating great #ImageScanningMicroscopy images.
Thanks @iitalk.bsky.social @erc.europa.eu @genoainstruments.bsky.social and #PNRR RNA&GeneTheraphy for support. See you at #Mifobio2025

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Genoa Instruments | Microscopy @genoainstruments.bsky.social · 10d

🚀 Ever wished your confocal could do super-resolution?
Now you can — with the PRISM Light kit. Image Scanning Microscopy with SPAD-array in commercial confocal systems: 🧠 Neuroscience 🔬 Deep Imaging 🌈 Multicolor ISM. Check out Figure 3: www.nature.com/articles/s41...

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Genoa Instruments | Microscopy @genoainstruments.bsky.social · 24d

Why it matters:
FLISM gives you both structure and function — super-resolved lifetime imaging with superior SNR, even using the same laser, optics, and detector hardware.

👉 FLISM = super-resolution + time-resolved imaging, in one system.

📖 Check out Figure 2 from: www.nature.com/articles/s41...

A robust and versatile platform for image scanning microscopy enabling super-resolution FLIM - Nature Methods

A single-photon detector array enables robust and versatile image scanning microscopy (ISM) on any confocal microscope. This implementation makes super-resolution FLIM possible and eases a transition…

www.nature.com

Genoa Instruments | Microscopy @genoainstruments.bsky.social · 24d

🔬 What happens when ISM meets FLIM?
You get FLISM – Fluorescence Lifetime Image Scanning Microscopy.

✅ Higher resolution & SNR vs confocal
✅ Live-cell friendly — super-res at 10× lower light
✅ High temporal resolution

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Genoa Instruments | Microscopy @genoainstruments.bsky.social · Aug 28

Back to the bench after the summer break? ☀️🔬 At Genoa Instruments, we’re making sure your imaging doesn’t slow down. Our PRISM-Light units are ready to ship, with a new system just coming out of final assembly — designed to power your microscopy with precision and reliability.

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Genoa Instruments | Microscopy @genoainstruments.bsky.social · Jun 17

A SPAD array in any microscope… or to snap a quick photo! 📸
Here’s our Alberto Diaspro live from the 12th International Weber Symposium, showing that with photons — anything is possible (almost).

#GenoaInstruments #SPAD #PhotonHumor #WeberSymposium2025 #Microscopy #ScienceWithStyle

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Genoa Instruments | Microscopy @genoainstruments.bsky.social · Jun 15

🔬 From Heidelberg to Genoa – Next Stop: Weber Symposium!

🧪 For those interested, remote demos will be available during the conference, and we’re also hosting in-lab sessions on the afternoon of June 18.

📩 Let us know if you’d like to meet or book a demo!

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Genoa Instruments | Microscopy @genoainstruments.bsky.social · Jun 13

ELMI 2025, it’s been real. Plenty of workshops, great conversations with researchers, and lots of microscope companies in one place. We’re glad we joined. See you at the next one!

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Genoa Instruments | Microscopy @genoainstruments.bsky.social · May 27

🔬 Genoa Instruments @ ELMI 2025 – Let’s Meet in Heidelberg! We’re looking forward to sharing what we’ve been working on, and to connecting with the microscopy community in such an inspiring setting. 📩 Want to meet? Drop us a line or come say hi at the conference! #ELMI2025

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Genoa Instruments | Microscopy @genoainstruments.bsky.social · May 19

What a day! Last Friday, we had the pleasure of joining the celebrations for the #InternationalDayOfLight, hosted by the Nanoscopy & NIC@IIT team at Palazzo della Borsa in Genoa. A big thank you to all the attendees and the organizers!

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Genoa Instruments | Microscopy @genoainstruments.bsky.social · May 12

#InternationalDayOfLight #GenoaInstruments #PhotonResolvedMicroscopy #Innovation #BeyondTheInvisible #Genova

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Genoa Instruments | Microscopy @genoainstruments.bsky.social · May 12

A special occasion to explore the science and beauty of light, and to share how technologies like PRISM—our photon-resolved microscope—are expanding the frontiers of biomedical imaging.

We’d love to see you there! 🚀

📍 Find all the event details here: www.diasprolab.it

DiasproLab 1985-2025

SEELIFE BEYOND THE INVISIBLE Shaping Light, Collecting Photons, Forming Images, Exploring Life. We are a RESEARCH group of BIOPHYSICISTS merging different backgrounds physics, bioengineering,…

www.diasprolab.it

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Genoa Instruments | Microscopy @genoainstruments.bsky.social · May 12

Genoa Instruments celebrates the International Day of Light!

On May 16th, we’ll be taking part in “Beyond the Invisible”, an event curated by Alberto Diaspro at Palazzo della Borsa, Genoa, in collaboration with the Genoa Chamber of Commerce.

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Genoa Instruments | Microscopy @genoainstruments.bsky.social · May 9

☀️ Spring vibes at our campus in Genoa! If you’re passionate about photonics, life sciences, or simply love solving complex problems in a beautiful place… we’re always open to meeting great people. Next time you walk across that lawn, it might be to join us!

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Genoa Instruments | Microscopy @genoainstruments.bsky.social · May 6

🎉 Orgogliosi di annunciare che il nostro Alberto Diaspro ha ricevuto il prestigioso Premio Montale Fuori di Casa 2025, sezione “In Limine”, per il suo straordinario contributo nel superare i confini tra scienza e cultura.

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Reposted by Genoa Instruments | Microscopy

VicidominiLab @vicidominilab.bsky.social · Apr 30

#ImageScanningMicroscopy inherently encodes aberration info. No extra hardware needed! A #CNN decodes Zernike modes directly from a single acquisition. A new data-driven path to #AdaptiveOptics in #LSM!
doi.org/10.1364/BOE....
#PhotonResolvedMicroscopy #SPADarray
@iitalk.bsky.social @erc.europa.eu

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Genoa Instruments | Microscopy @genoainstruments.bsky.social · Apr 23

Siamo in copertina! Felici di essere citati da Repubblica tra le #startup nate nei laboratori @iitalk.bsky.social, protagoniste nel trasformare la ricerca scientifica in impatto concreto.

🔗 Leggi l’articolo: www.repubblica.it/tecnologia/2...

#GenoaInstruments #IIT #StartupDeepTech #Microscopia

Tutte le startup dell’Istituto Italiano di Tecnologia

Sono 37 le imprese innovative nate dai laboratori IIT, per un totale di 140 milioni di euro circa raccolti e più di 250 persone operative. Tra queste, IAMA The…

www.repubblica.it

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Genoa Instruments | Microscopy @genoainstruments.bsky.social · Mar 27

💡 Check out Figure 3 form: www.mdpi.com/2076-3417/13... — this is how we push the limits of optical microscopy.

🚀 Ready to take your super-resolution imaging further? Let’s connect.

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Genoa Instruments | Microscopy @genoainstruments.bsky.social · Mar 27

Why ISM?

✨ Super-resolution at the right scale – Capture chromatin-bound complexes at the scale they operate.
🔍 More flexible than STED/STORM – No complex sample preparation or special fluorophores required.
📊 Gentler imaging, higher signal retention, reducing photodamage.

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Genoa Instruments | Microscopy @genoainstruments.bsky.social · Mar 27

With PRISM-Light, recent studies demonstrated how ISM enables superior colocalization analysis of PRC1, PRC2, and H3K27me3 in chromatin, revealing spatial patterns essential for gene regulation. ISM is revolutionizing nanoscale molecular interaction studies.

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Genoa Instruments | Microscopy @genoainstruments.bsky.social · Mar 27

What if you could resolve protein interactions at the chromatin level—at the exact spatial scale of PcG complexes?

🧬 ISM for Functional Colocalization Studies

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Genoa Instruments | Microscopy @genoainstruments.bsky.social · Mar 21

Su #sole24ore l’intervista di Raoul De Forcade al nostro Simonluca Piazza. Parliamo di PRISM e della nostra missione: rendere la super-risoluzione accessibile a più ricercatori e centri di ricerca. 📖 Leggi su Il Sole 24 Ore – Nord Ovest. Grazie a @iitalk.bsky.social

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Genoa Instruments | Microscopy @genoainstruments.bsky.social · Mar 18

#SPAD #SuperResolution #OpticalBiopsy #PRISMlight #CornealImaging #BiomedicalImaging

Genoa Instruments | Microscopy @genoainstruments.bsky.social · Mar 18

With PRISM-Light, real-time optical biopsy is within reach, enabling researchers and clinicians to study cellular processes in fresh tissues like never before.

🚀 Let’s talk about how this could transform advanced diagnostics and tissue engineering!

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Genoa Instruments | Microscopy @genoainstruments.bsky.social · Mar 18

🌟 What makes this possible?
✅ Enhanced signal collection → Up to 8x better signal for deeper tissue imaging
✅ Unmatched spatial resolution → Down to 100 nm resolution
✅ Minimal photodamage → 70% lower light exposure compared to conventional methods

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