Lightnews — Scholar-powered news

Houming Chen @hmchen93.bsky.social · Aug 9

Happy to share our latest manuscript about Brassinosteroid recognition 😎 hope it offers a broad and intensive understanding of BR ligands--BRI1-LIKE receptors mechanism.

bioRxiv Plant Bio @biorxiv-plants.bsky.social · Aug 9

A mechanistic framework for the recognition of chemically diverse brassinosteroids by BRI1-family receptor kinases https://www.biorxiv.org/content/10.1101/2025.08.08.669299v1

2 3

Reposted by Houming Chen

Michael Hothorn @structplantbio.bsky.social · Aug 9

Our latest on brassinosteroid signaling: Ligand binding spectrum, specificity & selectivity of all BR receptors in Arabidopsis. By @albertocaregnato.bsky.social , @hmchen93.bsky.social and our great chemistry collaborators Mirek Kvasnica, Jana Oklestkova and Mirek Strnad.

1 29 53

Reposted by Houming Chen

Michael Hothorn @structplantbio.bsky.social · Jul 11

Nice analysis of ITPK and VIH inositol pyrophophate kinase over-expression lines in Arabidopsis. onlinelibrary.wiley.com/doi/10.1111/...

Enhancing inositol pyrophosphate accumulation in plants alters growth, phosphate homeostasis, and insect herbivory

This research investigates the physiological and biochemical impacts of increasing inositol pyrophosphates, molecules involved in plant phosphate sensing and jasmonic acid signaling, in Arabidopsis. ...

onlinelibrary.wiley.com

1 4

Reposted by Houming Chen

Simon Snoeck @simonsnoeck.bsky.social · Jul 9

Shedding light on the structure-function mechanisms of LRR-RPs. Our research merges #AlphaFold3, years of literature and functional validation to reveal diverse ligand-binding mechanisms and a conserved co-receptor association mechanism. www.biorxiv.org/content/10.1...

1 15 28

Reposted by Houming Chen

Nature Reviews Molecular Cell Biology @natrevmcb.nature.com · May 19

New Online! Mechanisms of auxin action in plant growth and development

Mechanisms of auxin action in plant growth and development

Nature Reviews Molecular Cell Biology, Published online: 19 May 2025; doi:10.1038/s41580-025-00851-2The phytohormone auxin coordinates plant growth by forming local maxima and gradients through cell-to-cell transport and metabolic control. Recent research has identified novel signalling mechanisms involving extracellular auxin perception and auxin-mediated cyclic AMP production.

bit.ly

3 13

Houming Chen @hmchen93.bsky.social · May 13

novel and in-depth work 👍🏻

Jian-Pu 韩 @jian-pu.bsky.social · May 11

Delighted to share one piece of my postdoc work in preprint: Through forward genetic screening for suberin deposition in root endodermis, we identified SUBER GENE 1 (SBG1) by GWAS as a novel regulator for suberization by interacting with Type One Protein Phosphatase. www.biorxiv.org/content/10.1...

3

Reposted by Houming Chen

Nature Plants @natplants.nature.com · Jan 21

New Article: "Structural mechanism underlying PHO1;H1-mediated phosphate transport in Arabidopsis" rdcu.be/d62pA

Phosphate transporter PHO1: cryo-EM, biochemical & physiological analysis. Molecular and regulatory mechanism of transport mediated by the SPX–EXS family. #PlantScience

1 7 16

Reposted by Houming Chen

bioRxiv Plant Bio @biorxiv-plants.bsky.social · Nov 28

BPMs regulate Arabidopsis seedling development by promoting auxin-independent degradation of the Aux/IAA protein IAA10 https://www.biorxiv.org/content/10.1101/2024.11.26.625463v1

After germination, seedlings undergo etiolated development (skotomorphogenesis), enabling them to gr

www.biorxiv.org

3 4

Reposted by Houming Chen

Prof. Keiko Torii @keikoutorii.bsky.social · Dec 11

Perspectives on a co-option of a familiar signaling pathway for embryo patterning, where phosphorylation of SCREAM by MPK3/6 triggers different outcomes. But..Symmetric Cell Division is EXCITING and essential for generating a mirror-symmetric Guard Cell pair😘🌱.
www.nature.com/articles/s41...

Yoda screams again - Nature Plants

Nature Plants - Yoda screams again

www.nature.com

7 11

Houming Chen @hmchen93.bsky.social · Nov 18

Thanks bro. 😎

Houming Chen @hmchen93.bsky.social · Nov 17

(4) Overall, we proved phosphorylation by ERECTA-YODA pathway positively regulates SCRM in embryos, which differs with the phosphor-dependent degradation model found in stomata. That's a novel example of how MAPK signaling differentially regulates a single target in distinct developmental contexts.

Houming Chen @hmchen93.bsky.social · Nov 17

(3) Reported stomatal gain-of-function scrm-D (R236H) mutant brings overproliferation of stomata by disrupting the interaction with MPK3/6. However, scrm-D leads to a severe loss of zygotic polarity & impaired embryo. Phosphor-inactive SCRM 6A can rescue stomatal phenotypes, but not in the embryo.

Houming Chen @hmchen93.bsky.social · Nov 17

(2) SCRM functions in parallel with the well-known target WRKY2 of the ERECTA-YODA signaling pathway during embryo development. Double mutation of SCRM and WRKY2 results in phenotypes strikingly similar to those of yoda, along with a nearly complete loss of the WOX8-YFP signal in vivo.

Houming Chen @hmchen93.bsky.social · Nov 17

(1) SCRM is a key factor in promoting zygotic polarity by activating the embryo-specific gene WOX8 in Arabidopsis zygotes and early embryos.

Reposted by Houming Chen

Houming Chen @hmchen93.bsky.social · Nov 17

Super excited to announce that our SCRM story is officially published!!! 🎉🎉🎉

Want to discover the exciting new functions of ICE1/SCRM?

Want to dive into the latest model of plant embryo initiation?

Don’t miss out—check it out here:
nph.onlinelibrary.wiley.com/doi/10.1111/...

Phosphorylation‐dependent activation of the bHLH transcription factor ICE1/SCRM promotes polarization of the Arabidopsis zygote

In Arabidopsis thaliana, the asymmetric cell division (ACD) of the zygote gives rise to the embryo proper and an extraembryonic suspensor, respectively. This process is controlled by the ERECTA-YODA...

nph.onlinelibrary.wiley.com

5 6 15

Houming Chen @hmchen93.bsky.social · Nov 17

Super excited to announce that our SCRM story is officially published!!! 🎉🎉🎉

Want to discover the exciting new functions of ICE1/SCRM?

Want to dive into the latest model of plant embryo initiation?

Don’t miss out—check it out here:
nph.onlinelibrary.wiley.com/doi/10.1111/...

Phosphorylation‐dependent activation of the bHLH transcription factor ICE1/SCRM promotes polarization of the Arabidopsis zygote

In Arabidopsis thaliana, the asymmetric cell division (ACD) of the zygote gives rise to the embryo proper and an extraembryonic suspensor, respectively. This process is controlled by the ERECTA-YODA...

nph.onlinelibrary.wiley.com

5 6 15