Author | Lightnews

Kent Søe

@kentsoe.bsky.social

62 followers 54 following 6 posts

Strong interest for #bone #research and #osteoclast in the context of #osteoporosis, #breastcancer, and #prostatecancer. @SDU.DK @OUHhospital @SUND_SDU

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Kent Søe @kentsoe.bsky.social · Aug 4

New paper out in JBMRPlus !
Using a time-lapse co-culture approach with #osteoclasts and reversal cells, we show that reversal cells prefer pits over trenches, but that intermediate #CatK inhibition boosts their attraction and maturation into #osteoblasts.
track.smtpsendmail.com/9032119/c?p=...

Cathepsin K inhibitors promote osteoclast-osteoblast communication and engagement of osteogenesis

Abstract. Cathepsin K inhibitors are well known for their inhibitory activity against bone resorption but were also reported to preserve bone formation in

track.smtpsendmail.com

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Kent Søe @kentsoe.bsky.social · Feb 16

@osteoporosis-nl.bsky.social

Kent Søe @kentsoe.bsky.social · Feb 16

Do we make the best of the synergistic potential between basic and clinical scientists? This is the topic we as members of the Basic and Clincal Science Action Groups of @ectssociety.bsky.social (ECTS) and ECTS Academy discuss in this paper!
rdcu.be/d9WxL
@asbmr.bsky.social @ifmrs.bsky.social

Basic and Clinical Scientists Working Together—Do We Make the Best of Both Worlds?

rdcu.be

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Kent Søe @kentsoe.bsky.social · Feb 13

It is "osteoclast appreciation day" every day in my lab 😁

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Kent Søe @kentsoe.bsky.social · Jan 26

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Kent Søe @kentsoe.bsky.social · Jan 26

If you are interested in the impact of long non-coding RNA and uRNA on #human #osteoclast differentiation and #bone resorption, you may be interested in our paper published late last year - Open Access
www.nature.com/articles/s41...

Stage-specific modulation of multinucleation, fusion, and resorption by the long non-coding RNA DLEU1 and miR-16 in human primary osteoclasts - Cell Death & Disease

Cell Death & Disease - Stage-specific modulation of multinucleation, fusion, and resorption by the long non-coding RNA DLEU1 and miR-16 in human primary osteoclasts

www.nature.com

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