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Mauricio Martins @mamartins83.bsky.social · 21d

🔬 🧫 🧬 The Martins lab at UF Scripps has openings at the Staff Scientist and Research Assistant levels. Our group is developing practical and scalable interventions to cure HIV infection. 🔬 🧫 🧬

Apply using the links below.

explore.jobs.ufl.edu/en-us/job/53...

explore.jobs.ufl.edu/en-us/job/53...

University of Florida - Details - Research Assistant II - Martins Lab

explore.jobs.ufl.edu

Mauricio Martins @mamartins83.bsky.social · Sep 5

Our lab is growing! 🧬 🧫 🔬

We are looking for a Staff Scientist to work on the development of practical and scalable immune interventions against HIV/AIDS.

#hiv #hivcure #immunology #virology #immunotherapy #science #genetherapy #AAV

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Mauricio Martins @mamartins83.bsky.social · Sep 5

Congratulations Camila and Team! This is an amazing achievement!

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Mauricio Martins @mamartins83.bsky.social · Sep 3

I'm so happy to see this published. Thank you @consigliocr.bsky.social for your amazing contributions!

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Reposted by Mauricio Martins

Immunology Podcast @immunologypodcast.com · Aug 18

Dr. Amir Ardeshir and a team in Dr. @mamartins83.bsky.social's lab at @wertheimufscripps.bsky.social used AAV vectors to generat#HIV1="https://go.nature.com/4lwHts2" class="hover:underline text-blue-600 dark:text-sky-400" target="_blank" rel="noopener">e #HIV1 immunity in infant rhesus macaques!

Article: https://go.nature.com/4lwHts2
Episode with discussion: https://bit.ly/4mIESvZ

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Mauricio Martins @mamartins83.bsky.social · Aug 19

Thank you for highlighting our work!

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Reposted by Mauricio Martins

Nature @nature.com · Jul 31

Nature research paper: Determinants of successful AAV-vectored delivery of HIV-1 bNAbs in early life

go.nature.com/46C1xWa

Determinants of successful AAV-vectored delivery of HIV-1 bNAbs in early life - Nature

A single dose of an adeno-associated virus vector encoding an HIV-1 broadly neutralizing antibody given shortly after birth results in persistent antibody expression and protection from infection in rhesus macaque models of human HIV-1 transmission through breastfeeding and sexual intercourse.

go.nature.com

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Reposted by Mauricio Martins

Infectious Diseases @infectiousdz.bsky.social · Aug 5

"Evidence is growing that some HIV-infected infants, if given antiretroviral drugs early in life, are able to suppress their viral loads to undetectable levels and then come off the medicine."
www.wired.com/story/the-fi...

The First Widespread Cure for HIV Could Be in Children

Evidence is growing that some HIV-infected infants, if given antiretroviral drugs early in life, are able to suppress their viral loads to undetectable levels and then come off the medicine.

www.wired.com

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Mauricio Martins @mamartins83.bsky.social · Aug 4

I really enjoyed this WIRED article on the prospects of curing pediatric HIV. Grateful to see our work on AAV-vectored delivery of HIV bNAbs featured. I hope it can move toward clinical trials as a potential “one-and-done” strategy to treat HIV infection in children.
www.wired.com/story/the-fi...

The First Widespread Cure for HIV Could Be in Children

Evidence is growing that some HIV-infected infants, if given antiretroviral drugs early in life, are able to suppress their viral loads to undetectable levels and then come off the medicine.

www.wired.com

Mauricio Martins @mamartins83.bsky.social · Jul 31

Thanks, Rachel! 😊

Mauricio Martins @mamartins83.bsky.social · Jul 30

wertheim.scripps.ufl.edu/2025/07/30/g...

#GeneTherapy #NIH #Pediatrics #HIV #GlobalHealth #GatesFoundation #GlobalHealth

@nature.com @niaidnews.bsky.social @billgates.bsky.social

Gene Therapy May Block HIV Transmission During Breastfeeding, Study Shows » The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology » The Wertheim UF Scripps Institute » Univ...

A new study in Nature that finds a gene therapy against HIV given at birth can protect breastfeeding babies from infection with a single dose.

wertheim.scripps.ufl.edu

Mauricio Martins @mamartins83.bsky.social · Jul 30

I hope this strategy can be evaluated in clinical trials. If this works in humans, it could dramatically simplify efforts to prevent and treat pediatric HIV infections.

Mauricio Martins @mamartins83.bsky.social · Jul 30

In sum, we show that multi-year HIV-1 immunity can be generated in primates from a one-time AAV vector administration at birth–one of the most consistent times of interaction between healthcare providers and the mother-baby pair.

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Mauricio Martins @mamartins83.bsky.social · Jul 30

Our study also showed that, compared to adult and juvenile macaques, neonates were more likely to benefit from AAV-vectored delivery of HIV-1 bNAbs because of their tolerance-prone immune systems.

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Mauricio Martins @mamartins83.bsky.social · Jul 30

Importantly, neonatal gene therapy with AAV/bNAb vectors significantly protected both infant and pre-adolescent macaques from simian-HIV infection in mucosal challenge models designed to simulate HIV-1 transmission through breastfeeding and sexual intercourse.

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Mauricio Martins @mamartins83.bsky.social · Jul 30

I’m happy to share the latest paper from my lab published in Nature today.
nature.com/articles/s41...
We show in rhesus macaques that a single dose of AAV/bNAb vectors at birth was safe and resulted in bNAb levels in plasma that lasted for up to 4 years without redosing.

Determinants of successful AAV-vectored delivery of HIV-1 bNAbs in early life - Nature

A single dose of an adeno-associated virus vector encoding an HIV-1 broadly neutralizing antibody given shortly after birth results in persistent antibody expression and protection from infection in r...

nature.com

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Mauricio Martins @mamartins83.bsky.social · Jul 29

The department of Immunology and Microbiology at The Herbert Wertheim UF Scripps Institute for Biomedical Innovation and Technology is looking for a new faculty member.
wertheim.scripps.ufl.edu/departments/...
We are accepting applications until November 15, 2025.
apply.interfolio.com/163182

Immunology and Microbiology » The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology » The Wertheim UF Scripps Institute » University of Florida

Cutting-edge immunology applied to cancer, HIV, autoimmunity, inflammation, SARS-CoV-2 and beyond. The Immunology and Microbiology faculty of The Wertheim UF Scripps Institute are devoted to explainin...

wertheim.scripps.ufl.edu

Mauricio Martins @mamartins83.bsky.social · Jul 21

Here is a new science award for female Brazilian scientists working in the US.

The ScientistA Award recognizes Brazilian women in the areas of life sciences, medicine and the environment who are developing research in the United States.

🏆 Prize: $2,000

dimensionssciences.org/scientista-a...

Dimensions Sciences

Scholarships, mentorships, coaching and training for scientists, enabling career growth and industry transitions.

dimensionssciences.org