Lightnews — Scholar-powered news

Nils Kroemer @nbkroemer.bsky.social · 1d

Published now (after long last & 10 citations). Although tVNS does not alter food reward ratings in healthy people, it acutely improved liking ratings in patients with MDD (also correlated with anhedonia). #neuroskyence 🩺

Work w/ @akuehnel.bsky.social
www.sciencedirect.com/science/arti...

9 23

Reposted by Nils Kroemer

JJ @jjodx.bsky.social · 1d

One of my two last (ever) papers on tDCS:
Does anodal tDCS over M1 really enhance motor sequence learning? A non-replication of earlier findings in a double-blind, pre-registered large-sample study in humans
www.medrxiv.org/content/10.1...

Does anodal tDCS over M1 really enhance motor sequence learning? A non-replication of earlier findings in a double-blind, pre-registered large-sample study in humans

Background Transcranial direct current stimulation (tDCS) is one of the most widely used noninvasive neuromodulation methods. Despite its popularity, some recent studies highlighted issues about the r...

www.medrxiv.org

4 16 31

Reposted by Nils Kroemer

Rocio Servin @rocioservin.bsky.social · 11d

We’re hiring!
My new Gut–Brain Axis Lab at Northwestern is looking for a Research Technologist 2 to help build the lab and explore how the nervous system shapes gut health and disease.
🔬 Apply here: myhr.northwestern.edu/psp/hrnu/EMP...

Sign In

JavaScript is required. This web browser does not support JavaScript or JavaScript in this web browser is not enabled.

myhr.northwestern.edu

2 23 45

Reposted by Nils Kroemer

Becca Williams @beccasue99.bsky.social · 2d

NEW PREPRINT ❗️

A slightly different take on the old problem of #apathy - we find evidence that apathy is linked to confidence on action outcomes 🎯

🧠This confidence may be underpinned by self-regulation of prefrontal superficial pyramidal neurons

#neuroskyence

www.biorxiv.org/content/10.1...

Apathy as a Loss of Prior Precision on Action Outcomes

Apathy is common in neurological disease, associated with poor prognosis and limited treatments. Current models posit that goal-directed actions are reduced because costs or effort outweigh the expect...

www.biorxiv.org

3 6 18

Reposted by Nils Kroemer

Nature Metabolism @natmetabolism.nature.com · 2d

REVIEW | The insulin signalling network 🧪

JG Burchfield, A Diaz-Vegas & DE James

A detailed overview of insulin signaling and its dysfunction, highlighting new therapeutic opportunities

The insulin signalling network - Nature Metabolism

In this Review, the authors provide a detailed overview of insulin signalling and its dysfunction, highlighting new therapeutic opportunities.

bit.ly

2 1

Reposted by Nils Kroemer

TMSMultiLab @tmsmultilab.bsky.social · 2d

To find out about how #TMS #BrainStim users collect, analyse & share their data, we've made a very brief TMS survey:

forms.gle/83Abpj5F8qzd...

It should take you less than 5 minutes & does not ask for any personal information.

We'll use the answers to plan our future work.

Please share!

🙏🙏🙏

⚡

TMSMultiLab survey

TMSMultiLab is a community of ~70 researchers using transcranial magnetic stimulation (TMS). We aim to share methods code and data, to reach consensus & encourage best practice in TMS research methods...

forms.gle

8 5

Reposted by Nils Kroemer

Serge Ahmed @sergeahmed.bsky.social · 2d

Ethanol ingestion via frugivory in wild chimpanzees

Chimpanzees typically eat ~4.5 kilograms of fruit per day, corresponding to an estimated ethanol ingestion of 14 grams (±9), or the equivalent of 1.4 (±0.9) standard drinks by international standards.

www.science.org/doi/10.1126/...

2 3

Reposted by Nils Kroemer

Ann Kennedy @antihebbiann.bsky.social · 3d

Finally out: our recent work with Nick Betley is a view into how the brain reshapes its behavior in the face of competing survival needs- and also a potential angle on treatment targets for enduring pain.

A brief rundown...

www.nature.com/articles/s41...

A parabrachial hub for need-state control of enduring pain - Nature

Activity in a set of parabranchial neurons in the mouse brain is increased during chronic pain, predicts coping behaviour, and can be modulated by circuits activated by survival threats.

www.nature.com

9 40 120

Reposted by Nils Kroemer

Andrea Ganna @andganna.bsky.social · 3d

💥 New preprint & our first RCT! 💥

Does an extremely high or low BMI polygenic score influence weight loss after a diet intervention?

GENEROOS is a 6-month randomized diet vs. control trial testing if genetic predisposition to higher BMI affects weight loss in overweight adults

2 6 27

Reposted by Nils Kroemer

Frankie D Heyward @frankiedheyward.bsky.social · 3d

I’m excited to share our new preprint! We built a single-nucleus multiomic (snRNA-seq+snATAC-seq) atlas of leptin receptor-expressing hypothalamic neurons (LepRᴴʸᵖᵒ) and identified conserved cis-regulatory elements overlapping human obesity-linked variants and eQTLs🧠🧬
www.biorxiv.org/content/10.1...

Single-nucleus transcriptional and chromatin accessibility profiling of mouse hypothalamic LepRb neurons reveals cell type-specific cis-regulatory elements linked to human obesity

Leptin receptor-expressing hypothalamic neurons (LepRHypo) are key regulators of energy balance, yet a comprehensive, cell type-resolved, chromatin accessibility map of these neurons is lacking. We pr...

www.biorxiv.org

7 21

Reposted by Nils Kroemer

Nicole Rust @nicolecrust.bsky.social · 4d

Please spread the word! I am recruiting a PhD student this cycle (Fall 2026 start) to join my team in a new venture: the neuroscience of mood.

If you are curious to learn more, this short talk provides a good overview of why, what and how.

www.youtube.com/watch?v=gjIK...

Nicole Rust - The representation of mood in the primate insula (May 6, 2025)

YouTube video by Simons Foundation

www.youtube.com

1 39 60

Nils Kroemer @nbkroemer.bsky.social · 4d

Cheers, Maria 🥂. We should celebrate as well at some point 🎉

1 3

Reposted by Nils Kroemer

Alice Seffen @aliceseffen.bsky.social · 4d

Many people aim to eat less meat, but some situations make it harder to stick to this goal. In our new study, we explored how individuals evaluate different self-control strategies in terms of effectiveness and feasibility. Check it out, it's OA :-)

doi.org/10.1016/j.fo...

Easy at home, difficult at the restaurant: Perceived effectiveness and feasibility of self-control strategies for reducing meat consumption

A growing number of individuals desire to cut down on meat consumption, yet translating this intention into action poses challenges. Self-control stra…

www.sciencedirect.com

1 1 2

Reposted by Nils Kroemer

Philippe Jawinski @pjawinski.bsky.social · 5d

🧠 Why do some brains age faster than others?
🧬 Our new Nature Aging study of over 56,000 participants explores the genetics of the “brain age gap” — the difference between your brain’s biological and chronological age.
nature.com/articles/s43587-025-00962-7

Thread below 👇

Genome-wide analysis of brain age identifies 59 associated loci and unveils relationships with mental and physical health - Nature Aging

This genomic study of magnetic resonance imaging-based brain age in 56,348 people identifies 59 genetic loci, links brain aging to mental and physical health, and suggests high blood pressure and type 2 diabetes as causal factors of brain aging.

nature.com

1 13 24

Reposted by Nils Kroemer

Nora Newcombe @noranewcombe.bsky.social · 5d

Dense longitudinal neuroimaging reveals individual brain change trajectories: Trends in Cognitive Sciences www.cell.com/trends/cogni...

Dense longitudinal neuroimaging reveals individual brain change trajectories

Longitudinal measurements of brain structure and function are critical for understanding how humans change over time. Traditional longitudinal approaches sample sparsely across large windows of time t...

www.cell.com

11 32

Reposted by Nils Kroemer

Carmen Sandi @carmensandi10.bsky.social · 5d

Very happy to share our new paper in Biological Psychiatry, showing that Urolithin A reverses high anxiety by repairing mitochondrial function in the nucleus accumbens.

Big kudos to first co-authors David Mallet & Doğukan Ülgen, our amazing team, and collaborators!

🔗 Paper: doi.org/10.1016/j.bi...

Redirecting

doi.org

3 13 71

Nils Kroemer @nbkroemer.bsky.social · 5d

Patients with irritable bowel syndrome often have impaired glucose metabolism. A personalized low-glycemic diet can achieve therapeutic benefits comparable to established treatments.
Schmelter et al, Gut 🩺
gut.bmj.com/content/earl...

Impaired glucose metabolism in irritable bowel syndrome: personalised low-glycaemic diet as potential therapeutic target

We read with great interest the recent study by Gilliam-Vigh et al demonstrating significant transcriptomic alterations in the intestinal mucosa of individuals with type 2 diabetes (T2D), particularly...

gut.bmj.com

2 2

Reposted by Nils Kroemer

AJ Simon @ayejaysimon.bsky.social · 5d

New preprint alert!

We used connectome-based predictive modeling in a transdiagnostic sample to identify brain network correlates of wide array of behavioral measures. We also identify where networks supporting cognition overlap with those linked to diagnostically related clinical symptomatology.

Transdiagnostic connectome-based predictive modeling of many behavioral phenotypes reveals brain network mediators of clinical-cognitive relationships

Connectome-based predictive modeling (CPM) applied to functional MRI connectivity data can identify brain networks that vary with behavioral measures across subjects. The prediction strength also prov...

www.biorxiv.org

5 9

Reposted by Nils Kroemer

Vivienne Hazzard @vhazzard.bsky.social · 6d

So grateful to the teens who shared their experiences with us to help develop the Co-occurring Insecurities Model, a new working theoretical model to explain the link between #foodinsecurity and #bingeeating. Full text: authors.elsevier.com/a/1loUMiVKTo...

1 4 13

Reposted by Nils Kroemer

Julia M. Rohrer @dingdingpeng.the100.ci · 6d

Happy to announce that I'll give a talk on how we can make rigorous causal inference more mainstream 📈

You can sign up for the Zoom link here: tinyurl.com/CIIG-JuliaRo...

3 55 140

Reposted by Nils Kroemer

Neuroengineering @neuroengineering.bsky.social · 7d

Precision Neuroscience published their high-density ECoG in Nature Biomed. Eng.

The startup shows a 1,024-channel grid implanted through a cortical slit in pigs, and intraoperative neural recordings and stimulation in five humans at sub-mm resolution.

#neuroskyence @precisionneuro.bsky.social

Minimally invasive implantation of scalable high-density cortical microelectrode arrays for multimodal neural decoding and stimulation - Nature Biomedical Engineering

A 1,024-channel microelectrode array is delivered to the brain cortex via a minimally invasive incision in the skull and dura, and allows recording, stimulation and neural decoding across large portions of the brain in porcine models and human neurosurgical patients.

www.nature.com

7 27

Reposted by Nils Kroemer

Boris Bernhardt @borismontreal.bsky.social · 10d

🚨 New paper in Nature Methods:
HippoMaps: multiscale cartography of the human hippocampus

Open-source tools & data to explore structure and function of the 🍤🧠 (histology, in/ex vivo MRI, iEEG)

Led by @jordandekraker.bsky.social

docs: hippomaps.readthedocs.io
paper: doi.org/10.1038/s415...

3 37 80

Reposted by Nils Kroemer

Quentin Huys @docqhuys.bsky.social · 10d

New #job alert! Clinical research fellow / postdoc in #computationalpsychiatry at the @mpc-comppsych.bsky.social / @uclqsion.bsky.social and UCL psychiatry. We will aim to understand the computations engaged by serotonin in the treatment of depression. Please re-sky. www.ucl.ac.uk/work-at-ucl/...

UCL – University College London

UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).

www.ucl.ac.uk

1 35 35

Reposted by Nils Kroemer

Benjamin Kay @benjaminkay.bsky.social · 11d

Ever wondered if your interesting brain-behavior correlation was over- or under-estimated due to head motion, but were afraid to ask? We’ve created a motion impact score for detecting spurious brain-behavior associations, now available in Nature Communications!
doi.org/10.1038/s414...

1 23 55

Nils Kroemer @nbkroemer.bsky.social · 12d

Congratulations 👏. At some point in life, it feels better how one hardly grows 'old', also in the German academic system 😄

2