Reproductive BioMedicine Online
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Reproductive BioMedicine Online
@rbmonline.bsky.social
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An international journal dedicated to biomedical research on human conception and the welfare of the human embryo. https://www.linktr.ee/rbmo/ #ReproMed #IVF #Embryology #Fertility
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Given that serum LH levels do not predict outcomes, routine serum LH measurements could be omitted in standard endometrial preparation for single euploid frozen embryo transfer in a programmed FET cycle utilizing vaginal progesterone for luteal phase support.

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Our new Countercurrent discusses the manner in which reproductive medicine can meet its challenges; in cultivating practical wisdom, we strengthen the foundation of human-centered reproductive science that seeks not just progress and results, but meaning and responsibility.

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A clinically relevant number of PQBs are euploid, PQBs can result in live births and euploid transfer is associated with lower miscarriage rates. In combination, this suggests that PQBs should not be routinely discarded, particularly if they are prior-tested using PGT-A.

doi.org/10.1016/j.rb...

This work reflects real clinical practice, presenting a proof of concept methodology that IVF centres may employ to establish their own thresholds which after validation, can be used for patient counselling and to facilitate the workload of the IVF laboratory.

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#RBMOeditorschoice
Selected as Editor’s Choice from our October issue, this novel study estimates the minimum number of oocytes retrieved based on the follicular diameter on the day of triggering final oocyte maturation in women undergoing ovarian stimulation for IVF.

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#RBMOeditorschoice
This investigation into the embryo laboratory outcomes in ANA-positive but anti-ENA-negative patients, shows that presence of ANA is associated with a decrease in 2PN embryos, cleavage embryos, 2PN cleavage embryos, high-quality embryos and blastocysts.

doi.org/10.1016/j.rb...
This study presents new evidence to show that, despite suboptimal development, late mature MIIs can create high-quality blastocysts, offering additional opportunities for future family building.

RBMO subscribers can read the full paper from our in-press articles section now

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This new study for our Male Reproductive Health and Fertility section shows a positive association between serum magnesium and sperm concentration, total sperm count, total number of motile spermatozoa, as well as serum AMH.

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#Andrology #SerumMagnesium
Despite reduced levels of SPEVs in their azoospermic samples, the elevated protein content warrants attention; denser biomolecular exosomal packaging in human testicular tissues may indicate the critical state of the intricate process of intratesticular sperm production.

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In this new study of the potential for practical application of GenAI technology, experienced fertility specialists outperformed two leading AI language models in providing accurate and reliable responses to complex clinical questions.

doi.org/10.1016/j.rb...
Available for free from issue 51.4 now, this review shows:

• Cryoprotectants and additives protect SSC during cryopreservation.
• Cryoprotectant cocktails increase protective effects.
• SSC cryopreservation should be further explored to develop novel cryoprotectants.

doi.org/10.1016/j.rb...
The Autumn RBMO Digest is out now – our quarterly publication of highlights and specially recommended papers from recent issues of RBMO.

Plus, a section profile on our Female Reproductive Health and Fertility section, with Editor Frederick Licciardi.

bit.ly/rbmoDigestAu...
This open access Short Communication presents data associating maternal occupational exposure to certain types of endocrine disrupting chemicals during pregnancy and reproductive hormone levels in adult sons.

doi.org/10.1016/j.rb...
The results from this analysis into prevalence and impact of PCOS in China, show infertility attributable to PCOS as increasing as a faster rate than the global burden of the disease; making PCOS a major public health problem and a public health priority that needs attention

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This new review calls for an interdisciplinary approach involving gynecologists, reproductive endocrinologists, and fertility specialists to navigate the complexities of fertility preservation in endometriosis.

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our LinkedIn version here, which you can subscribe to separately:

www.linkedin.com/pulse/rbmo-i...
☕ Settle in to your Sunday morning with a nice big coffee and catch up with the latest journal highlights and new perspectives on recent papers in the October edition of RBMO Insights.

Read it from our email version here: sh1.sendinblue.com/ais0e855z9pf...

.....or if you prefer............👇
This study investigates the effect of a web-based, multi-component decision aid on key elements of informed decision-making among couples at risk of transmitting a genetic disease to their offspring in a multi-centre randomized controlled trial.

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The study demonstrates the ability of AI tool ERICA (Embryo Ranking Intelligent Classification Algorithm) to enhance the reliability of embryo selection; increasing accuracy, and reducing subjectivity and bias.

doi.org/10.1016/j.rb...

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#RBMOeditorsChoice #ClinicalEmbryology #AIinIVF
AI simulation training can play a valuable role in embryology, similar to fields like surgery. By recreating repeatable real-life scenarios, simulations enhance skill development, providing controlled environments to practice and improve techniques.

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#RBMOeditorsChoice #AIinIVF
Selected as an Editor’s Choice article from our October issue, this article adds some valuable insights into the potential for predictive AI tools to influence the decision-making process of clinical embryologists.
doi.org/10.1016/j.rb...

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#RBMOeditorsChoice #ClinicalEmbryology #AIinIVF
This new Countercurrent Contribution from Paul Pirtea and Baris Ata challenges the commonly used 7mm threshold for endometrial thickness in ART, arguing that it should complement a comprehensive assessment and plan of personalized, data-driven care, not rigid thresholds.

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This study describes Swedish 'single mothers by choice' receiving funded treatments, comparing background, treatment motives, experiences of the psychosocial evaluation, support needs, reflections on motherhood (including during COVID-19), and post-birth circumstances.

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Georges Raad and colleagues highlight the diagnostic value of sperm characteristics in predicting embryological outcomes.

Post-preparation sperm vacuolization shows significant prediction of fertilization, and mitochondrial activity in raw semen predicts blastulation rates

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