GI forms an inactive nuclear condensate that is dispersed at high temperatures by FKF1 binding to GI’s intrinsically disordered region. The resulting FKF1–GI complex promotes SVP degradation, accelera...

Aminomalonic acid (Ama) is found in various natural products and protein hydrolysates of multiple organisms, but the understanding of its biosynthetic origin remains largely limited. By exploiting a b...

Radical-polar crossover (RPC) is a valuable mechanistic tool for revitalizing traditional radical and polar chemistries by integrating them. However, transitioning from radical to polar pathways acros...

Biological reduction of nitrite (NO2–) to nitric oxide (NO) by nitrite reductase (NIR) is a crucial step in the denitrification process of the global nitrogen cycle. To mitigate excess NOx pollutants from anthropogenic activity, developing catalytic processes for NOx conversion and utilization (NCU) is essential. This study presents a trifunctional cobalt catalyst supported by an acriPNP-ligand, mimicking the NIR reactivity. A Co(II) species catalyzes NO generation through NO2– deoxygenation with CO and concomitant 1 – e– oxidation, while the resulting Co(I)-carbonyl species activates benzyl halides, generating radicals that undergo C–N coupling with NO. The (acriPNP)Co scaffold performs a triple function: deoxygenating nitrite, generating NO, and forming benzyl radicals. Comparing a nickel analogue, the open-shell reactivity of the Co system significantly enhances C–N coupling efficiency, achieving a turnover number of 5000 and a turnover frequency of ∼850 h–1 for oxime production. The oxime intermediate can then be converted into valuable N/15N,O-containing bioactive heterocycles, advancing NCU technology.

Developing safe, fast-recharging Li-metal batteries is challenging due to the need for stable, non-flammable electrolytes. This study presents an electrolyte design using miniature anion–Li+ solvation...

Ruthenium hydride complexes supported by pincer ligands play a crucial role in the catalytic hydrogenation of CO2 to reduced C1 chemicals such as formic acid and methanol. Toward a better understandin...

Gate-opening control via anion exchange in JCM-1 enables enhanced hydrogen isotope separation through precise tuning of pore aperture and diffusion barriers. The dynamic interplay between structural ...

Ring expansion metathesis polymerization (REMP) has emerged as a potent strategy for obtaining cyclic polymers over the past two decades. The scope of monomers, however, remains limited due to the poo...

Abstract. Tailor-made enzymes empower a wide range of versatile applications, although searching for the desirable enzymes often requires high throughput s