Allison Williams
@allisonmck.bsky.social
Assistant Professor @ UCSF
Investigator @ CZ Biohub San Francisco
Williamslab: https://williamslab.ucsf.edu
Investigator @ CZ Biohub San Francisco
Williamslab: https://williamslab.ucsf.edu
It was such a fabulous visit with wonderful and engaging talks from all the speaker. This was also student organized which made it so much more special.
Just one week away! 🚨
Northwestern’s 16th Annual Biophysics Symposium is happening Friday, Sept 12. A full day of talks, a career panel, and student/postdoc research presentations.
📝 Register: lnkd.in/g62_mVXy
🔗 Details: lnkd.in/gm2jRTWZ
#Northwestern #Biophysics
Northwestern’s 16th Annual Biophysics Symposium is happening Friday, Sept 12. A full day of talks, a career panel, and student/postdoc research presentations.
📝 Register: lnkd.in/g62_mVXy
🔗 Details: lnkd.in/gm2jRTWZ
#Northwestern #Biophysics
September 18, 2025 at 9:05 PM
It was such a fabulous visit with wonderful and engaging talks from all the speaker. This was also student organized which made it so much more special.
Reposted by Allison Williams
Phosphorylation State Dictates Bacterial Stressosome Assembly and Function https://www.biorxiv.org/content/10.1101/2025.03.04.640944v1
March 6, 2025 at 2:34 PM
Phosphorylation State Dictates Bacterial Stressosome Assembly and Function https://www.biorxiv.org/content/10.1101/2025.03.04.640944v1
Also thank you chatGPT for helping to shorten my post to fit word limit restrictions here :)
March 6, 2025 at 7:41 AM
Also thank you chatGPT for helping to shorten my post to fit word limit restrictions here :)
🎉 Huge thanks to our incredible team, collaborators, and supporters! 🎉
Thanks to the powerful imaging capabilities @ UCSF!
Grateful to the NIH and CZ Biohub for making this research possible!
www.biorxiv.org/content/10.1...
#StructuralBiology #CryoEM #Microbiology #Phosphorylation #NIH #CZBiohub
Thanks to the powerful imaging capabilities @ UCSF!
Grateful to the NIH and CZ Biohub for making this research possible!
www.biorxiv.org/content/10.1...
#StructuralBiology #CryoEM #Microbiology #Phosphorylation #NIH #CZBiohub
Phosphorylation State Dictates Bacterial Stressosome Assembly and Function
Bacterial pathogens rely on their ability to sense and respond to environmental stressors to survive and maintain virulence. The stressosome, a 1.8-megadalton nanomachine, serves as a critical sensor ...
www.biorxiv.org
March 6, 2025 at 7:38 AM
🎉 Huge thanks to our incredible team, collaborators, and supporters! 🎉
Thanks to the powerful imaging capabilities @ UCSF!
Grateful to the NIH and CZ Biohub for making this research possible!
www.biorxiv.org/content/10.1...
#StructuralBiology #CryoEM #Microbiology #Phosphorylation #NIH #CZBiohub
Thanks to the powerful imaging capabilities @ UCSF!
Grateful to the NIH and CZ Biohub for making this research possible!
www.biorxiv.org/content/10.1...
#StructuralBiology #CryoEM #Microbiology #Phosphorylation #NIH #CZBiohub
🚨New preprint!🚨 How do bacteria sense stress and activate survival pathways? We solved multiple cryo-EM structures of Listeria stressosomes in different phosphorylation states, revealing how phosphorylation fine-tunes stress responses and virulence. 🦠🔬
📄 Read more: www.biorxiv.org/content/10.1...
📄 Read more: www.biorxiv.org/content/10.1...
Phosphorylation State Dictates Bacterial Stressosome Assembly and Function
Bacterial pathogens rely on their ability to sense and respond to environmental stressors to survive and maintain virulence. The stressosome, a 1.8-megadalton nanomachine, serves as a critical sensor ...
www.biorxiv.org
March 6, 2025 at 7:22 AM
🚨New preprint!🚨 How do bacteria sense stress and activate survival pathways? We solved multiple cryo-EM structures of Listeria stressosomes in different phosphorylation states, revealing how phosphorylation fine-tunes stress responses and virulence. 🦠🔬
📄 Read more: www.biorxiv.org/content/10.1...
📄 Read more: www.biorxiv.org/content/10.1...
Phosphorylation is the switch that controls bacterial stressosomes! Our cryo-EM study shows how stepwise phosphorylation activates Listeria stressosomes to trigger survival pathways. A finely tuned mechanism—reminiscent of eukaryotic signalosomes! 🦠⚡
📢 Check it out: www.biorxiv.org/content/10.1...
📢 Check it out: www.biorxiv.org/content/10.1...
Phosphorylation State Dictates Bacterial Stressosome Assembly and Function
Bacterial pathogens rely on their ability to sense and respond to environmental stressors to survive and maintain virulence. The stressosome, a 1.8-megadalton nanomachine, serves as a critical sensor ...
www.biorxiv.org
March 6, 2025 at 7:20 AM
Phosphorylation is the switch that controls bacterial stressosomes! Our cryo-EM study shows how stepwise phosphorylation activates Listeria stressosomes to trigger survival pathways. A finely tuned mechanism—reminiscent of eukaryotic signalosomes! 🦠⚡
📢 Check it out: www.biorxiv.org/content/10.1...
📢 Check it out: www.biorxiv.org/content/10.1...
Bacteria adapt to stress using massive nanomachines! 🛠️🦠 Our new work reveals how phosphorylation controls the Listeria stressosome, linking structural changes to survival and virulence. A bacterial signaling hub with striking parallels to eukaryotic inflammasomes!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Phosphorylation State Dictates Bacterial Stressosome Assembly and Function
Bacterial pathogens rely on their ability to sense and respond to environmental stressors to survive and maintain virulence. The stressosome, a 1.8-megadalton nanomachine, serves as a critical sensor ...
www.biorxiv.org
March 6, 2025 at 7:19 AM
Bacteria adapt to stress using massive nanomachines! 🛠️🦠 Our new work reveals how phosphorylation controls the Listeria stressosome, linking structural changes to survival and virulence. A bacterial signaling hub with striking parallels to eukaryotic inflammasomes!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Allison Williams
A good man has left this world. May he be remembered, because his life was a blessing.
James Harrison, whose blood donations saved over 2 million babies, has died
Harrison, whose plasma contained a rare antibody, rolled up his sleeve 1,173 times from 1954 to 2018. The Australian is credited with helping 2.4 million babies and advancing scientific research.
www.npr.org
March 4, 2025 at 2:15 AM
A good man has left this world. May he be remembered, because his life was a blessing.
Reposted by Allison Williams
Do you want the NIH, policymakers and lawmakers to
reverse the cap on how we invest in American science infrastructure? Consider joining me in signing this petition: chng.it/kK2HMP5pGk
reverse the cap on how we invest in American science infrastructure? Consider joining me in signing this petition: chng.it/kK2HMP5pGk
The world’s platform for change
Change.org is the world’s largest petition platform, using technology to empower more than 200 million users to create the change they want to see.
chng.it
March 2, 2025 at 4:27 PM
Do you want the NIH, policymakers and lawmakers to
reverse the cap on how we invest in American science infrastructure? Consider joining me in signing this petition: chng.it/kK2HMP5pGk
reverse the cap on how we invest in American science infrastructure? Consider joining me in signing this petition: chng.it/kK2HMP5pGk
Reposted by Allison Williams
Monday: Never gave you up
Tuesday: Never let you down
Wednesday: Never ran around and deserted you
Thursday: Never made you cry
Friday: Never said goodbye
Saturday: Never told a lie and hurt you
(Dedicated to all the fantastic colleagues at NIH, NSF, and CDC)
Tuesday: Never let you down
Wednesday: Never ran around and deserted you
Thursday: Never made you cry
Friday: Never said goodbye
Saturday: Never told a lie and hurt you
(Dedicated to all the fantastic colleagues at NIH, NSF, and CDC)
February 24, 2025 at 2:23 PM
Monday: Never gave you up
Tuesday: Never let you down
Wednesday: Never ran around and deserted you
Thursday: Never made you cry
Friday: Never said goodbye
Saturday: Never told a lie and hurt you
(Dedicated to all the fantastic colleagues at NIH, NSF, and CDC)
Tuesday: Never let you down
Wednesday: Never ran around and deserted you
Thursday: Never made you cry
Friday: Never said goodbye
Saturday: Never told a lie and hurt you
(Dedicated to all the fantastic colleagues at NIH, NSF, and CDC)
Reposted by Allison Williams
Speaking of healthcare. Let's make @bsky.app the platform that fights misinformation. Some great follows are @drsusanoliver.bsky.social @jsm2334.bsky.social @therealtruther.bsky.social
Let's get them more followers and engagement than other platforms and let health science accounts find a home
Let's get them more followers and engagement than other platforms and let health science accounts find a home
January 25, 2025 at 5:55 PM
Speaking of healthcare. Let's make @bsky.app the platform that fights misinformation. Some great follows are @drsusanoliver.bsky.social @jsm2334.bsky.social @therealtruther.bsky.social
Let's get them more followers and engagement than other platforms and let health science accounts find a home
Let's get them more followers and engagement than other platforms and let health science accounts find a home
“There comes a time when one must take a position that is neither safe, nor politic, nor popular, but he must take it because conscience tells him it is right.”
– Martin Luther King Jr.
My ancestors knew that the hardest choices are the most necessary. #Courage #Integrity #Conscience
January 18, 2025 at 6:21 PM
“There comes a time when one must take a position that is neither safe, nor politic, nor popular, but he must take it because conscience tells him it is right.”
– Martin Luther King Jr.
My ancestors knew that the hardest choices are the most necessary. #Courage #Integrity #Conscience
Did anyone else in San Francisco think they misread the tornado emergency alert at 6:15 AM this morning? Last week it was a tsunami warning, and now a tornado—yikes!
December 14, 2024 at 5:50 PM
Did anyone else in San Francisco think they misread the tornado emergency alert at 6:15 AM this morning? Last week it was a tsunami warning, and now a tornado—yikes!
Reposted by Allison Williams
Liver metabolizes high fructose corn syrup to fructose, which leads to increase production of LPC lipids that promote tumor growth.
#Glycotime
www.nature.com/articles/s41...
#Glycotime
www.nature.com/articles/s41...
Dietary fructose enhances tumour growth indirectly via interorgan lipid transfer - Nature
Dietary fructose enhances tumour growth in animal models of melanoma, breast cancer and cervical cancer indirectly via metabolite transfer.
www.nature.com
December 11, 2024 at 8:42 AM
Liver metabolizes high fructose corn syrup to fructose, which leads to increase production of LPC lipids that promote tumor growth.
#Glycotime
www.nature.com/articles/s41...
#Glycotime
www.nature.com/articles/s41...
Reposted by Allison Williams
The restoration of the Notre Dame Cathedral is a nice reminder that catastrophes do not last forever, and what's broken can also be fixed.
December 7, 2024 at 3:55 AM
The restoration of the Notre Dame Cathedral is a nice reminder that catastrophes do not last forever, and what's broken can also be fixed.
Exciting times in the Williams lab! Big congratulations to Javarcia for successfully passing his qualifying exam! 🎉👏 #MSTP Journey #TeamScience #UCSF!
December 7, 2024 at 5:46 AM
Exciting times in the Williams lab! Big congratulations to Javarcia for successfully passing his qualifying exam! 🎉👏 #MSTP Journey #TeamScience #UCSF!
“Thrilled to join Bluesky! My social media hiatus has come to an end. Looking forward to collaborating, exploring, laughing and celebrating with my amazing colleagues. 🌟 #NewBeginnings #TeamScience #BlueSkyThinking
November 17, 2024 at 1:32 AM
“Thrilled to join Bluesky! My social media hiatus has come to an end. Looking forward to collaborating, exploring, laughing and celebrating with my amazing colleagues. 🌟 #NewBeginnings #TeamScience #BlueSkyThinking