Ali Darwish, MD, FACP
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darwishmd.bsky.social
Ali Darwish, MD, FACP
@darwishmd.bsky.social
120 followers 34 following 120 posts
Board Certified Internal Medicine Doctor in LA/OC
#MedSky #CardioSky
Not Medical Advice. For Information Only.

https://linktr.ee/darwishmd
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darwishmd.bsky.social
📊 New study suggests GLP-1 receptor agonists may reduce overall cancer risk in people with obesity #GLP1 #Obesity #Oncology #medsky

🤔 Do you think it’s the weight loss, another mechanism of the drug, or a combination driving this effect?

www.jwatch.org/na59176/2025...
nejmJW_1L_RGB-b
www.jwatch.org
September 15, 2025 at 10:15 AM
darwishmd.bsky.social
New JAMA study: Semaglutide and tirzepatide reduce risk of heart failure hospitalization or death by >40% in patients with obesity-related HFpEF and type 2 diabetes—no meaningful difference between the two drugs.

jamanetwork.com/journals/jam...

#health #medicine #MedEd #MedTwitter #CardioTwitter
Semaglutide and Tirzepatide in Patients With Heart Failure With Preserved Ejection Fraction
This study evaluates the effectiveness and safety of semaglutide and tirzepatide in patients with cardiometabolic heart failure with preserved ejection fraction in clinical practice.
jamanetwork.com
August 31, 2025 at 11:51 PM
darwishmd.bsky.social
Crystal waters, stunning views! Lake Como is pure magic. #LakeComo #ItalyTravel #ScenicBeauty #LakesideVibes #TravelItaly #NatureLovers #italia
August 26, 2025 at 8:59 PM
darwishmd.bsky.social
Six Books That Shaped My Journey: Lessons in Grit, Giving, and Moving Forward

Check out: open.substack.com/pub/globalro...
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#LifeLessons #lifestyle #giving #motivation #meditations #Philosophy #medicine #MedEd #MedTwitter #CardioTwitter #BooksWorthReading
Six Books That Shaped My Journey: Lessons in Grit, Giving, and Moving Forward
Connecting the Dots Between Ancient Stoicism, Modern Science, and the Path to Healing Others
open.substack.com
August 26, 2025 at 12:27 PM
Reposted by Ali Darwish, MD, FACP
nature.com
A brain-imaging study of people with amputated arms has upended a long-standing belief

go.nature.com/3Jp9NPG
The brain’s map of the body is surprisingly stable — even after a limb is lost
Study challenges the textbook idea that the brain region that processes body sensations reorganizes itself after limb amputation.
go.nature.com
August 21, 2025 at 10:07 AM
darwishmd.bsky.social
🧘‍♀️ Feeling overwhelmed by daily stress? MBSR (Mindfulness-Based Stress Reduction) is a science-backed 8-week program that teaches you to respond rather than react.

open.substack.com/pub/globalro...

#MBSR #Mindfulness #StressReduction #MentalHealth #Wellness #Meditation #StressManagement
Finding Peace in the Storm: How Mindfulness-Based Stress Reduction Can Transform Your Daily Life
A science-backed approach to managing life's inevitable stresses
open.substack.com
August 19, 2025 at 10:45 AM
darwishmd.bsky.social
Sam Altman says we're in an AI bubble but that "smart people get overexcited about a kernel of truth." www.cnbc.com/2025/08/18/o...

Market correction incoming or just honest assessment?

#AI #OpenAI #TechBubble #SamAltman
OpenAI's Sam Altman sees AI bubble forming as industry spending surges
OpenAI CEO Sam Altman thinks the artificial intelligence market is in a bubble, similar to the dotcom bubble, he recently told reporters.
www.cnbc.com
August 18, 2025 at 11:38 PM
darwishmd.bsky.social
AI designed 2 novel antibiotics atom-by-atom to kill drug-resistant gonorrhoea & MRSA! Could this spark a #SecondGoldenAge in antibiotic discovery? How soon will AI revolutionize medicine on a global scale? 🤖💊

open.substack.com/pub/globalro...

#Superbugs #AntibioticResistance #AIinMedicine
Reprogramming Antibiotics: How AI is Outsmarting Superbugs
The AI Breakthrough That Could End Drug-Resistant Infections
open.substack.com
August 15, 2025 at 7:49 AM
darwishmd.bsky.social
Apple’s smart-home future looks straight out of Pixar: think an iPad on an animating arm that dances, follows, and converses. How will you feel when your tech starts acting—and feeling—human?

open.substack.com/pub/globalro...

#SmartHome #AI #Apple #Robotics #Siri #HomeTech #artificialintelligence
Apple’s Next Big Bet: An AI Robot for Your Living Room
Apple’s smart home is about to get a personality
open.substack.com
August 13, 2025 at 11:22 PM
darwishmd.bsky.social
Claude for Education could change how kids learn — instant feedback, deeper dives, & curiosity over memorization

But here’s the question: if AI becomes a learning co-pilot, will kids still learn to think on their own? Or will not using it be a disadvantage?

#AIinEducation #FutureOfLearning #EdTech
August 13, 2025 at 11:32 AM
darwishmd.bsky.social
I just started a Substack: Global Rounds with Ali Darwish globalrounds.substack.com?r=26r0iz&utm...
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#lifestyle #travel #health #photography #health #medicine #MedEd #MedTwitter #CardioTwitter #medicaleducation
Global Rounds with Ali Darwish | Substack
Physician. Dad. Traveler. Photographer. Global Rounds is my take on the world — in images, stories, and ideas worth sharing. Click to read Global Rounds with Ali Darwish, a Substack publication. Launc...
globalrounds.substack.com
August 11, 2025 at 6:23 AM
darwishmd.bsky.social
What are your thoughts on this? I can see the logic with an Apple - Perplexity Deal.
www.bloomberg.com/news/article... #ai #artificialintelligence #apple #perplexityai
Apple Executives Have Held Internal Talks About Buying AI Startup Perplexity
Apple Inc. executives have held internal discussions about potentially bidding for artificial intelligence startup Perplexity AI, seeking to address the need for more AI talent and technology.
www.bloomberg.com
July 16, 2025 at 5:00 PM
Reposted by Ali Darwish, MD, FACP
nature.com
A gene variant known to increase the risk of Alzheimer’s disease also makes people vulnerable to a host of other age-related brain disorders

go.nature.com/4eRJcGD
One potent gene raises risk of Alzheimer’s, Parkinson’s and other brain diseases
Massive proteomics database links gene variant APOE4 to chronic inflammation.
go.nature.com
July 16, 2025 at 9:01 AM
Reposted by Ali Darwish, MD, FACP
nature.com
Nature research paper: Eighteen million years of diverse enamel proteomes from the East African Rift

go.nature.com/44JrujP
Eighteen million years of diverse enamel proteomes from the East African Rift - Nature
The isolation of dental proteins from fossils deposited 1.5 million to 18 million years ago in the Turkana Basin in Kenya, a tropical region, demonstrate the promise of dental enamel for palaeoproteomic and evolutionary studies.
go.nature.com
July 16, 2025 at 10:41 AM
darwishmd.bsky.social
New: PURSUIT, a novel, once-daily oral molecule inhibitor, showed robust, dose-dependent effects on LDL-C and favorable safety in patients with hypercholesterolemia on moderate- or high-intensity statin treatment. bit.ly/3XG7Oe2 #health #medicine #MedEd #MedSky #CardioSky #medicaleducation
April 2, 2025 at 12:42 AM
darwishmd.bsky.social
1 in 5 adults have an Lp(a) level that is too high. Check out the infographic to learn more. bit.ly/3RxBF4F

#health #medicine #MedEd #MedSky #CardioSky #medicaleducation
March 31, 2025 at 7:17 PM
darwishmd.bsky.social
New Study: Cannabis Use Substantially Increases Risk of Heart Attack
📌 MI: Sixfold 🔺
📌 Ischemic Stroke: Fourfold 🔺
📌 Heart Failure: Twofold 🔺

www.acc.org/Latest-in-Ca...

#health #medicine #MedEd #MedSky #CardioSky #medicaleducation
Cannabis Use Substantially Increases Risk of Heart Attack - American College of Cardiology
www.acc.org
March 26, 2025 at 3:29 PM
darwishmd.bsky.social
The 2024 Clinical Practice Guideline focuses on the evaluation and management of Chronic Kidney Disease (CKD), emphasizing early detection and comprehensive management strategies. #health #medicine #MedEd #MedSky #CardioSky #medicaleducation
www.acpjournals.org
March 14, 2025 at 12:42 AM
darwishmd.bsky.social
Muvalaplin safely lowers high levels of lipoprotein(a), or Lp(a), results from the phase 2 KRAKEN trial show. www.medscape.com/viewarticle/... #MedEd #MedSky #CardioSky
New Pill Successfully Lowers Lp(a) Levels
Muvalaplin shows promise in lowering lipoprotein(a) levels, which are genetically determined and confer cardiovascular risk and for which no approved therapies currently exist.
www.medscape.com
March 13, 2025 at 7:17 PM
darwishmd.bsky.social
New Study: LAA Closure post-ablation led to:
⬇️ major bleeding vs. OAC (8.5% vs. 18.1%)
Noninferior for stroke, systemic embolism & death
www.nejm.org/doi/abs/10.1... #health #medicine #MedEd #MedSky #CardioSky
www.nejm.org
March 9, 2025 at 8:55 AM
darwishmd.bsky.social
New 2025 US guidelines for managing ACS (STEMI and NSTE-ACS) recommend intravascular imaging with OCT or IVUS during PCI for left main or complex lesions with a class IA recommendation #health #medicine #MedEd #MedSky #CardioSky #medicaleducation
February 28, 2025 at 8:17 PM
darwishmd.bsky.social
10 simple yet powerful strategies to transform your workday and boost productivity, including morning routines, task prioritization, and minimizing distractions. #productivity #worklife #GTD
10 Simple Ways to Transform Your Workday and Boost Productivity
Ten Easy Ways to Change Your Workday and Increase Productivity In the fast-paced workplace of today, increasing productivity is crucial for…
buff.ly
February 24, 2025 at 8:17 PM
Reposted by Ali Darwish, MD, FACP
nejm.org
Among patients with ventricular tachycardia and ischemic cardiomyopathy, catheter ablation as an initial therapy led to a lower risk of adverse outcomes than antiarrhythmic drug therapy. Full VANISH2 trial results and Research Summary: nej.md/3Z5ECOD

#MedSky #CardioSky
The New England Journal of Medicine Catheter Ablation for Ventricular Tachycardia A Research Summary based on Sapp JL et al. | 10.1056/NEJMoa2409501 | Published on November 16, 2024 Visual representations of the patients in the trial and the treatments they were assigned. Read the full Research Summary at NEJM.org.
February 23, 2025 at 8:41 PM
darwishmd.bsky.social
New BMJ guideline finds little to no benefit but potential harms for common spine injections. Recommends against most interventional procedures for chronic non-cancer spine pain. https://buff.ly/4i71SCm #health #medicine #MedEd #MedSky #CardioSky
February 21, 2025 at 1:42 AM
darwishmd.bsky.social
New AHA/ACC guidelines on competitive sports for athletes with heart conditions emphasize shared decision-making, updated sports classifications, and addressing racial disparities in screening. https://buff.ly/433gDSu #health #medicine #MedEd #MedSky #CardioSky
February 20, 2025 at 8:17 PM