@earlab.bsky.social
Reposted
How does the #cochlea achieve its spiral shape? @prakash-patterns.bsky.social @earlab.bsky.social &co show that the expression of adhesion & polarity proteins pattern the #OrganOfCorti and drive the compartment-specific organisation to achieve the cochlea spiral @plosbiology.org 🧪 plos.io/4nmD8IW
September 10, 2025 at 5:36 PM
How does the #cochlea achieve its spiral shape? @prakash-patterns.bsky.social @earlab.bsky.social &co show that the expression of adhesion & polarity proteins pattern the #OrganOfCorti and drive the compartment-specific organisation to achieve the cochlea spiral @plosbiology.org 🧪 plos.io/4nmD8IW
Reposted
#LatestPublication
Varsha from Dr. Raj Ladher’s lab finds that early inner ear fusion needs a hybrid EMT, where Grhl2/Sp8 remodel junctions to balance new contacts & tissue integrity.
This stunning image of an otocyst, taken by Varsha, featured on the cover!
bit.ly/4omQgOL
@earlab.bsky.social
Varsha from Dr. Raj Ladher’s lab finds that early inner ear fusion needs a hybrid EMT, where Grhl2/Sp8 remodel junctions to balance new contacts & tissue integrity.
This stunning image of an otocyst, taken by Varsha, featured on the cover!
bit.ly/4omQgOL
@earlab.bsky.social
October 16, 2025 at 11:56 AM
#LatestPublication
Varsha from Dr. Raj Ladher’s lab finds that early inner ear fusion needs a hybrid EMT, where Grhl2/Sp8 remodel junctions to balance new contacts & tissue integrity.
This stunning image of an otocyst, taken by Varsha, featured on the cover!
bit.ly/4omQgOL
@earlab.bsky.social
Varsha from Dr. Raj Ladher’s lab finds that early inner ear fusion needs a hybrid EMT, where Grhl2/Sp8 remodel junctions to balance new contacts & tissue integrity.
This stunning image of an otocyst, taken by Varsha, featured on the cover!
bit.ly/4omQgOL
@earlab.bsky.social
Reposted
#BestPaperAward
🎉 Congratulations to Raman Kaushik on being awarded the Zeeshan Khan Memorial Award 2025 (Runner Up) for the best paper published using the BLiSC Central Imaging Facility (CIFF) at the Bangalore Microscopy Course 2025.
@earlab.bsky.social @ncbsbangalore.bsky.social
🎉 Congratulations to Raman Kaushik on being awarded the Zeeshan Khan Memorial Award 2025 (Runner Up) for the best paper published using the BLiSC Central Imaging Facility (CIFF) at the Bangalore Microscopy Course 2025.
@earlab.bsky.social @ncbsbangalore.bsky.social
October 9, 2025 at 9:11 AM
#BestPaperAward
🎉 Congratulations to Raman Kaushik on being awarded the Zeeshan Khan Memorial Award 2025 (Runner Up) for the best paper published using the BLiSC Central Imaging Facility (CIFF) at the Bangalore Microscopy Course 2025.
@earlab.bsky.social @ncbsbangalore.bsky.social
🎉 Congratulations to Raman Kaushik on being awarded the Zeeshan Khan Memorial Award 2025 (Runner Up) for the best paper published using the BLiSC Central Imaging Facility (CIFF) at the Bangalore Microscopy Course 2025.
@earlab.bsky.social @ncbsbangalore.bsky.social
Reposted
#DBfeature #Drosophila 🪰
Slit-independent guidance of longitudinal axons by Drosophila Robo3
"A non-Slit-binding function of Robo3 Ig1 contributes to its axon guidance activity."
by Abigail Carranza, Timothy Evans et al
@timevansphd.bsky.social
sciencedirect.com/science/arti...
Slit-independent guidance of longitudinal axons by Drosophila Robo3
"A non-Slit-binding function of Robo3 Ig1 contributes to its axon guidance activity."
by Abigail Carranza, Timothy Evans et al
@timevansphd.bsky.social
sciencedirect.com/science/arti...
October 3, 2025 at 1:37 PM
#DBfeature #Drosophila 🪰
Slit-independent guidance of longitudinal axons by Drosophila Robo3
"A non-Slit-binding function of Robo3 Ig1 contributes to its axon guidance activity."
by Abigail Carranza, Timothy Evans et al
@timevansphd.bsky.social
sciencedirect.com/science/arti...
Slit-independent guidance of longitudinal axons by Drosophila Robo3
"A non-Slit-binding function of Robo3 Ig1 contributes to its axon guidance activity."
by Abigail Carranza, Timothy Evans et al
@timevansphd.bsky.social
sciencedirect.com/science/arti...
Reposted
link.growkudos.com/1efpeb7d8n4 A short article is now available at Kudos on our work @earlab.bsky.social at @ncbsbangalore.bsky.social about how the cochlea generates its pattern.
Cochlea generates patterns by interacting with neighbours
We wanted to understand how cells arrange into precise patterns as the cochlea develops its spiral shape. We found that the cochlea is divided into smaller domains, each organising independently whil...
link.growkudos.com
September 30, 2025 at 1:43 PM
link.growkudos.com/1efpeb7d8n4 A short article is now available at Kudos on our work @earlab.bsky.social at @ncbsbangalore.bsky.social about how the cochlea generates its pattern.
Reposted
The ear's organ of Corti as a model system of how developmental instructions coordinate across spatial scales so that tissues are sculpted reproducibly
📷 @prakash-patterns.bsky.social et al @tifr.res.in in @plosbiology.org
➡️ bpod.org.uk/archive/2025...
📷 @prakash-patterns.bsky.social et al @tifr.res.in in @plosbiology.org
➡️ bpod.org.uk/archive/2025...
September 17, 2025 at 4:49 PM
The ear's organ of Corti as a model system of how developmental instructions coordinate across spatial scales so that tissues are sculpted reproducibly
📷 @prakash-patterns.bsky.social et al @tifr.res.in in @plosbiology.org
➡️ bpod.org.uk/archive/2025...
📷 @prakash-patterns.bsky.social et al @tifr.res.in in @plosbiology.org
➡️ bpod.org.uk/archive/2025...
Reposted
The ear's organ of Corti as a model system of how developmental instructions coordinate across spatial scales so that tissues are sculpted reproducibly
📷 @prakash-patterns.bsky.social et al @tifr.res.in in @plosbiology.org
➡️ bpod.org.uk/archive/2025...
📷 @prakash-patterns.bsky.social et al @tifr.res.in in @plosbiology.org
➡️ bpod.org.uk/archive/2025...
September 17, 2025 at 5:29 PM
Reposted
How does the #cochlea achieve its spiral shape? @prakash-patterns.bsky.social @earlab.bsky.social &co show that the expression of adhesion & polarity proteins pattern the #OrganOfCorti and drive the compartment-specific organisation to achieve the cochlea spiral @plosbiology.org 🧪 plos.io/4nmD8IW
September 10, 2025 at 1:00 PM
How does the #cochlea achieve its spiral shape? @prakash-patterns.bsky.social @earlab.bsky.social &co show that the expression of adhesion & polarity proteins pattern the #OrganOfCorti and drive the compartment-specific organisation to achieve the cochlea spiral @plosbiology.org 🧪 plos.io/4nmD8IW
Reposted
How does the #cochlea achieve its spiral shape? @prakash-patterns.bsky.social @earlab.bsky.social &co show that the expression of adhesion & polarity proteins pattern the #OrganOfCorti and drive the compartment-specific organisation to achieve the cochlea spiral @plosbiology.org 🧪 plos.io/4nmD8IW
September 11, 2025 at 8:23 AM
How does the #cochlea achieve its spiral shape? @prakash-patterns.bsky.social @earlab.bsky.social &co show that the expression of adhesion & polarity proteins pattern the #OrganOfCorti and drive the compartment-specific organisation to achieve the cochlea spiral @plosbiology.org 🧪 plos.io/4nmD8IW
Reposted
#ResearchExplained
During embryo development, if cells fail to arrange or align correctly, organs could fail to function properly. Yet, cells somehow manage to find their place & align with remarkable precision.
Read here: bit.ly/46gbk2j
✏️Christeen Paulson
During embryo development, if cells fail to arrange or align correctly, organs could fail to function properly. Yet, cells somehow manage to find their place & align with remarkable precision.
Read here: bit.ly/46gbk2j
✏️Christeen Paulson
September 10, 2025 at 12:17 PM
#ResearchExplained
During embryo development, if cells fail to arrange or align correctly, organs could fail to function properly. Yet, cells somehow manage to find their place & align with remarkable precision.
Read here: bit.ly/46gbk2j
✏️Christeen Paulson
During embryo development, if cells fail to arrange or align correctly, organs could fail to function properly. Yet, cells somehow manage to find their place & align with remarkable precision.
Read here: bit.ly/46gbk2j
✏️Christeen Paulson
Reposted
#LatestPublication
In a latest study published in PLOS Genetics, Ramankaushik and team from Dr Raj Ladher's lab describe a new role for protocadherin-15 in patterning the hair cell.
🎉Congratulations to the team!
journals.plos.org/plosgenetics...
In a latest study published in PLOS Genetics, Ramankaushik and team from Dr Raj Ladher's lab describe a new role for protocadherin-15 in patterning the hair cell.
🎉Congratulations to the team!
journals.plos.org/plosgenetics...
Role of Pcdh15 in the development of intrinsic polarity of inner ear hair cells
Author summary Hearing, like other sensory modalities, is essential for animals to perceive and interact with their environment. The cochlea, the auditory sensory organ, develops under tight genetic r...
journals.plos.org
August 19, 2025 at 11:07 AM
#LatestPublication
In a latest study published in PLOS Genetics, Ramankaushik and team from Dr Raj Ladher's lab describe a new role for protocadherin-15 in patterning the hair cell.
🎉Congratulations to the team!
journals.plos.org/plosgenetics...
In a latest study published in PLOS Genetics, Ramankaushik and team from Dr Raj Ladher's lab describe a new role for protocadherin-15 in patterning the hair cell.
🎉Congratulations to the team!
journals.plos.org/plosgenetics...
InSDB-ISD Joint Meeting 2025 thenode.biologists.com/insdb-isd-jo...
InSDB-ISD Joint Meeting 2025 - the Node
The Indian Society of Developmental Biologists (InSDB) is hosting our 2025 meeting from December 14–17 at IISER Berhampur. This year will be a joint
thenode.biologists.com
July 29, 2025 at 9:16 AM
InSDB-ISD Joint Meeting 2025 thenode.biologists.com/insdb-isd-jo...
Reposted
We are looking for a new @thembauk.bsky.social Anne Warner Research Fellow (5 year post) to develop an independent research group in the area of cell and molecular biology of marine organisms here in #Plymouth 🔬🦠🧫🧬 mymba.mba.ac.uk/job-listing....
July 22, 2025 at 3:01 PM
We are looking for a new @thembauk.bsky.social Anne Warner Research Fellow (5 year post) to develop an independent research group in the area of cell and molecular biology of marine organisms here in #Plymouth 🔬🦠🧫🧬 mymba.mba.ac.uk/job-listing....
Mona’s work is now online - check it and we’re Lokku g forward to any comments you have.
A Novel Mouse Model Reveals a Role for Mitochondria in EarlyLineage Specification and Gastrulation https://www.biorxiv.org/content/10.1101/2025.07.14.664670v1
July 14, 2025 at 10:09 PM
Mona’s work is now online - check it and we’re Lokku g forward to any comments you have.
Reposted
Prof. Raj Ladher, president-InSDB and faculty @NCBS_Bangalore, will talk about cochlear morphogenesis at InSDB-ISD 2025! Raj's lab works on understanding the mechanisms that control inner ear development
#InSDB25 #InSDBISD25
@earlab.bsky.social @ncbsbangalore.bsky.social
#InSDB25 #InSDBISD25
@earlab.bsky.social @ncbsbangalore.bsky.social
June 23, 2025 at 6:02 AM
Prof. Raj Ladher, president-InSDB and faculty @NCBS_Bangalore, will talk about cochlear morphogenesis at InSDB-ISD 2025! Raj's lab works on understanding the mechanisms that control inner ear development
#InSDB25 #InSDBISD25
@earlab.bsky.social @ncbsbangalore.bsky.social
#InSDB25 #InSDBISD25
@earlab.bsky.social @ncbsbangalore.bsky.social
Reposted
Excited to welcome Prof Sally Dunwoodie as an invited speaker for InSDB-ISD 2025!
Sally's work focuses on identifying the genetic and environmental causes of congenital defects. She is also the president of @intlsocdiff.bsky.social.
Register now: insdb.in/events/insdb...
#InSDB25 #InSDBISD25
Sally's work focuses on identifying the genetic and environmental causes of congenital defects. She is also the president of @intlsocdiff.bsky.social.
Register now: insdb.in/events/insdb...
#InSDB25 #InSDBISD25
June 16, 2025 at 5:34 AM
Excited to welcome Prof Sally Dunwoodie as an invited speaker for InSDB-ISD 2025!
Sally's work focuses on identifying the genetic and environmental causes of congenital defects. She is also the president of @intlsocdiff.bsky.social.
Register now: insdb.in/events/insdb...
#InSDB25 #InSDBISD25
Sally's work focuses on identifying the genetic and environmental causes of congenital defects. She is also the president of @intlsocdiff.bsky.social.
Register now: insdb.in/events/insdb...
#InSDB25 #InSDBISD25
Our spotlight in this lovely study from Nita et al., on Fgfr2 localisation to the cilia.
Spotlight @jcb.org: Kaushik and Ladher @earlab.bsky.social discuss recent work from Nita et al. (rupress.org/jcb/article/...), describing how FGFR2 localization at primary #cilia affects FGFR signaling and highlighting the role of the cilium in a disease-related context. rupress.org/jcb/article/...
June 14, 2025 at 8:13 AM
Our spotlight in this lovely study from Nita et al., on Fgfr2 localisation to the cilia.
Reposted
#authorinterview Anubhav Prakash @prakash-patterns.bsky.social from Prof Raj Ladher lab @earlab.bsky.social, NCBS @ncbsbangalore.bsky.social talks about his work on "Pushing and pulling cells from chaos to order" biopatrika.com/academia/res... @natcomms.nature.com
Pushing and pulling cells from chaos to order - BioPatrika
Researcher Spotlight - Pulling cells: Using a combination of experiments and mathematical modelling, we show that the tuned differences in the mechanical properties of junctions can organise cells int...
biopatrika.com
June 4, 2025 at 4:18 AM
#authorinterview Anubhav Prakash @prakash-patterns.bsky.social from Prof Raj Ladher lab @earlab.bsky.social, NCBS @ncbsbangalore.bsky.social talks about his work on "Pushing and pulling cells from chaos to order" biopatrika.com/academia/res... @natcomms.nature.com
Reposted
📢Good news, students and postdocs!
Early bird student/postdoc registrants for InSDB-ISD25, who are members of InSDB, will be eligible for a reimbursement of the registration fee. This is supported by @intlsocdiff.bsky.social !
Don’t miss out - register early here: insdb.in/insdb-isd-re...
Early bird student/postdoc registrants for InSDB-ISD25, who are members of InSDB, will be eligible for a reimbursement of the registration fee. This is supported by @intlsocdiff.bsky.social !
Don’t miss out - register early here: insdb.in/insdb-isd-re...
June 2, 2025 at 11:43 AM
📢Good news, students and postdocs!
Early bird student/postdoc registrants for InSDB-ISD25, who are members of InSDB, will be eligible for a reimbursement of the registration fee. This is supported by @intlsocdiff.bsky.social !
Don’t miss out - register early here: insdb.in/insdb-isd-re...
Early bird student/postdoc registrants for InSDB-ISD25, who are members of InSDB, will be eligible for a reimbursement of the registration fee. This is supported by @intlsocdiff.bsky.social !
Don’t miss out - register early here: insdb.in/insdb-isd-re...
Reposted
📢Registrations are now open for InSDB-ISD 25!
This year, the meeting will take place at IISER BERHAMPUR from 15-17 December.
Join us this December!
Register here: insdb.in/insdb-isd-re...
@anups11.bsky.social
@earlab.bsky.social
@soniaqsen.bsky.social
This year, the meeting will take place at IISER BERHAMPUR from 15-17 December.
Join us this December!
Register here: insdb.in/insdb-isd-re...
@anups11.bsky.social
@earlab.bsky.social
@soniaqsen.bsky.social
May 16, 2025 at 4:56 AM
📢Registrations are now open for InSDB-ISD 25!
This year, the meeting will take place at IISER BERHAMPUR from 15-17 December.
Join us this December!
Register here: insdb.in/insdb-isd-re...
@anups11.bsky.social
@earlab.bsky.social
@soniaqsen.bsky.social
This year, the meeting will take place at IISER BERHAMPUR from 15-17 December.
Join us this December!
Register here: insdb.in/insdb-isd-re...
@anups11.bsky.social
@earlab.bsky.social
@soniaqsen.bsky.social
Reposted
#PhDone! 🎓 Congratulations Dr Surjit! 🎉
Surjit Singh Saini from Dr Raj Ladher's lab successfully defended his thesis!
🧵Scroll to learn about his work on understanding the development of inner-ear neurons 👂
(1/7)
@earlab.bsky.social
Surjit Singh Saini from Dr Raj Ladher's lab successfully defended his thesis!
🧵Scroll to learn about his work on understanding the development of inner-ear neurons 👂
(1/7)
@earlab.bsky.social
May 15, 2025 at 12:43 PM
#PhDone! 🎓 Congratulations Dr Surjit! 🎉
Surjit Singh Saini from Dr Raj Ladher's lab successfully defended his thesis!
🧵Scroll to learn about his work on understanding the development of inner-ear neurons 👂
(1/7)
@earlab.bsky.social
Surjit Singh Saini from Dr Raj Ladher's lab successfully defended his thesis!
🧵Scroll to learn about his work on understanding the development of inner-ear neurons 👂
(1/7)
@earlab.bsky.social
Reposted
#LatestPublication in @natcomms.nature.com by
Dr Raj Ladher & team show that fine-tuned junctional mechanics are vital for aligning polarity in chicken cochlea.
🎉Congratulations to the team!
@prakash-patterns.bsky.social @earlab.bsky.social
Read here: www.nature.com/articles/s41...
Dr Raj Ladher & team show that fine-tuned junctional mechanics are vital for aligning polarity in chicken cochlea.
🎉Congratulations to the team!
@prakash-patterns.bsky.social @earlab.bsky.social
Read here: www.nature.com/articles/s41...
Junctional force patterning drives both positional order and planar polarity in the auditory epithelia - Nature Communications
Sound is sensed in the cochlea through a precisely organised epithelium. Prakash and colleagues show cellular organisation results from differences in junction contractility, finding mechanics is suff...
www.nature.com
April 30, 2025 at 6:22 AM
#LatestPublication in @natcomms.nature.com by
Dr Raj Ladher & team show that fine-tuned junctional mechanics are vital for aligning polarity in chicken cochlea.
🎉Congratulations to the team!
@prakash-patterns.bsky.social @earlab.bsky.social
Read here: www.nature.com/articles/s41...
Dr Raj Ladher & team show that fine-tuned junctional mechanics are vital for aligning polarity in chicken cochlea.
🎉Congratulations to the team!
@prakash-patterns.bsky.social @earlab.bsky.social
Read here: www.nature.com/articles/s41...
Reposted
Epithelial fusion is mediated by a partial epithelial-mesenchymal transition https://www.biorxiv.org/content/10.1101/2025.04.21.649757v1
April 25, 2025 at 12:31 PM
Epithelial fusion is mediated by a partial epithelial-mesenchymal transition https://www.biorxiv.org/content/10.1101/2025.04.21.649757v1
Reposted
🌸This week RIKEN BDR is hosting researchers from the Bangalore Life Science Research Cluster (BLiSC), which includes @ncbsbangalore.bsky.social, inStem,
& TIGS, India. We are holding a joint meeting to further strengthen ties between BDR and BLiSC.
To the BLiSC delegation, welcome to Kobe!
& TIGS, India. We are holding a joint meeting to further strengthen ties between BDR and BLiSC.
To the BLiSC delegation, welcome to Kobe!
April 8, 2025 at 6:17 AM
🌸This week RIKEN BDR is hosting researchers from the Bangalore Life Science Research Cluster (BLiSC), which includes @ncbsbangalore.bsky.social, inStem,
& TIGS, India. We are holding a joint meeting to further strengthen ties between BDR and BLiSC.
To the BLiSC delegation, welcome to Kobe!
& TIGS, India. We are holding a joint meeting to further strengthen ties between BDR and BLiSC.
To the BLiSC delegation, welcome to Kobe!
Reposted
#NewComicAlert!
Sharing the latest comic of our collaboration with @TinkleMagazine, featuring ecologist Dr Meghna Krishnadas!
Dr Meghna's lab studies plants & their interactions with other species & the environment!🌱
Free Download: bit.ly/ncbsxtinklec...
Happy Reading!
#scicomm #sciencecomics
Sharing the latest comic of our collaboration with @TinkleMagazine, featuring ecologist Dr Meghna Krishnadas!
Dr Meghna's lab studies plants & their interactions with other species & the environment!🌱
Free Download: bit.ly/ncbsxtinklec...
Happy Reading!
#scicomm #sciencecomics
April 21, 2025 at 12:16 PM
#NewComicAlert!
Sharing the latest comic of our collaboration with @TinkleMagazine, featuring ecologist Dr Meghna Krishnadas!
Dr Meghna's lab studies plants & their interactions with other species & the environment!🌱
Free Download: bit.ly/ncbsxtinklec...
Happy Reading!
#scicomm #sciencecomics
Sharing the latest comic of our collaboration with @TinkleMagazine, featuring ecologist Dr Meghna Krishnadas!
Dr Meghna's lab studies plants & their interactions with other species & the environment!🌱
Free Download: bit.ly/ncbsxtinklec...
Happy Reading!
#scicomm #sciencecomics