Skyler Lentz
skylerlentz.bsky.social
Skyler Lentz
@skylerlentz.bsky.social
Critical Care and Emergency Physician, passionate about understanding and explaining abnormal physiology
Individualized PEEP:

Can you estimate optimal PEEP in any BMI with the simple equation of BMI/3?

Maybe!

Our new paper comparing esophageal pressure base transpulmonary pressure estimates of optimal PEEP (tPP of 0 +\-2) vs BMI/3 in OR patients

www.sciencedirect.com/science/arti...
Identifying Optimal Positive End-Expiratory Pressure by Body Mass Index Does Not Account for Natural Physiologic Variability in Pleural Pressure
Mechanical ventilation and selecting optimal positive end-expiratory pressure (PEEP) in patients across a wide range of body mass indexes (BMI) is cha…
www.sciencedirect.com
November 13, 2025 at 7:41 PM
How do you stop hydrocortisone once septic shock has resolved?

I tend to be an abrupt discontinuation kind of person, stop as soon as the pressors are off rather than taper (unless it’s been a prolonged course)

Restrospective evidence 👇

journals.lww.com/ccejournal/f...
Evaluation of Hydrocortisone Discontinuation Strategies in... : Critical Care Explorations
ility differ among patients with septic shock undergoing abrupt hydrocortisone discontinuation compared with gradual tapering. DESIGN, SETTING, AND PARTICIPANTS: A retrospective cohort study conduc...
journals.lww.com
August 18, 2025 at 7:22 PM
Which has a higher mortality?

1. Patient with EF 30% BP 80/56 with lactic acid 1.8, normal LFTs, and warm extremities

OR

2. Patient with EF 30% BP 100/70 with lactic acid 3.8, elevated LFTs and cool distal extremities
August 10, 2025 at 7:49 PM
Reposted by Skyler Lentz
Excited to share our updated review of ECMO for the emergency clinician! Grateful for my excellent co-authors who shared their extensive expertise & time: @skylerlentz.bsky.social, Cameron Upchurch, Jenelle Badulak, Brit Long, and @mgottliebmd.bsky.social

authors.elsevier.com/a/1lFOI2dHVQ...
authors.elsevier.com
June 11, 2025 at 6:54 PM
What in critical care medicine do you think makes the patient look better in the short term but is actually worse in the longer term?

25 yrs ago we might have said look my patient with ARDS and 12 ml/kg tidal volume is oxygenating better, so it must be superior to 6 ml/kg
June 5, 2025 at 1:38 AM
Intensivists and Respiratory Therapists: 🫁

What’s your go to tidal volume for the patient without ARDS and why?

6 ml/kg PBW
8 ml/kg PBW
10 ml/kg PBW
Something else?
May 10, 2025 at 7:03 PM
What’s the highest IPAP you’ll use with NIV in a patient with COPD and respiratory failure?

Before this trial I’d stop at ~ 20 cmH20, and think about intubating if not improving

After this trial:

Now up to 30 cmH20 may safely avoid intubation

jamanetwork.com/journals/jam...
Effect of Noninvasive Positive Pressure Ventilation on the Need for Endotracheal Intubation in COPD
This randomized clinical trial compares the effect of high-intensity noninvasive positive pressure ventilation (NPPV) vs low-intensity NPPV on the need for endotracheal intubation in patients with an ...
jamanetwork.com
March 30, 2025 at 2:17 AM
What’s the role of the osm gap in identifying toxic alcohol poisoning?

The con: We say it’s limited and all about the history and clinical course

www.sciencedirect.com/science/arti...
The Osmolal Gap Has a Limited Role in the Evaluation of Possible Toxic Alcohol Poisoning
www.sciencedirect.com
February 9, 2025 at 5:59 PM
What’s the highest temperature you’ve seen in clinical practice and what was the cause?
December 11, 2024 at 1:33 AM
🫀What happens when epinephrine is given before defibrillation in VT/VF arrest

journals.lww.com/ccmjournal/a...
a fire with the words way to add fuel written below it
ALT: a fire with the words way to add fuel written below it
media.tenor.com
November 9, 2024 at 7:08 PM
Failed extubation?

I like to think of it as an intubation vacation
December 21, 2023 at 12:51 PM