Tessa Green
@tessallator.bsky.social
computational immunology and transcriptomics @KiraGenBio| formerly @MIT@harvardmed and @hgsuuaw healthcare | she/her | 🏳️🌈👩🏻💻
tessadgreen.github.io
tessadgreen.github.io
Now accepting advice on long-distance dating an academic (success stories, anyone?)
I've struggled to announce this amidst so much dark & awful going on in the world, but with 1mo to go, I wanted to share that: (i) I finally graduated; (ii) In August, I'll begin as an assistant professor in the CS dept. of the National University of Singapore.
June 30, 2025 at 2:32 PM
Now accepting advice on long-distance dating an academic (success stories, anyone?)
Reposted by Tessa Green
A new #LongCovid clinical trial is enrolling for bezisterim, an investigational anti-inflammatory drug that crosses the blood-brain barrier.
It has been studied in neurological & neurodegenerative disorders, including Alzheimer’s & Parkinson’s. 1/
It has been studied in neurological & neurodegenerative disorders, including Alzheimer’s & Parkinson’s. 1/
June 20, 2025 at 7:48 PM
A new #LongCovid clinical trial is enrolling for bezisterim, an investigational anti-inflammatory drug that crosses the blood-brain barrier.
It has been studied in neurological & neurodegenerative disorders, including Alzheimer’s & Parkinson’s. 1/
It has been studied in neurological & neurodegenerative disorders, including Alzheimer’s & Parkinson’s. 1/
Reposted by Tessa Green
Comments returned on a grant application: one commenter said I lacked ML expertise and another wrote such a glowing paragraph about me that l'd like to staple it to my wall to look at when l'm feeling insecure
May 20, 2025 at 12:48 PM
Comments returned on a grant application: one commenter said I lacked ML expertise and another wrote such a glowing paragraph about me that l'd like to staple it to my wall to look at when l'm feeling insecure
Anyone have pro tips for emotionally processing the occasional realization that you’re reading a paper from a year ago and all of the patients who contributed samples to it are almost certainly dead?
May 15, 2025 at 5:21 PM
Anyone have pro tips for emotionally processing the occasional realization that you’re reading a paper from a year ago and all of the patients who contributed samples to it are almost certainly dead?
Reposted by Tessa Green
Again for those in the back:
👏🏼 PEM 👏🏼 is 👏🏼 NOT 👏🏼 deconditioning
Symptoms associated with effort expenditure in #LongCOVID, #MECFS and other energy limiting illnesses are physiological, not “preferential”
Thanks to @RobWust for this incredible work.
www.medrxiv.org/content/10.1...
👏🏼 PEM 👏🏼 is 👏🏼 NOT 👏🏼 deconditioning
Symptoms associated with effort expenditure in #LongCOVID, #MECFS and other energy limiting illnesses are physiological, not “preferential”
Thanks to @RobWust for this incredible work.
www.medrxiv.org/content/10.1...
Skeletal muscle properties in long COVID and ME/CFS differ from those induced by bed rest
Patients with long COVID and myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) suffer from a reduced exercise capacity, skeletal muscle abnormalities and post-exertional malaise (PEM), where...
www.medrxiv.org
May 7, 2025 at 7:30 AM
Again for those in the back:
👏🏼 PEM 👏🏼 is 👏🏼 NOT 👏🏼 deconditioning
Symptoms associated with effort expenditure in #LongCOVID, #MECFS and other energy limiting illnesses are physiological, not “preferential”
Thanks to @RobWust for this incredible work.
www.medrxiv.org/content/10.1...
👏🏼 PEM 👏🏼 is 👏🏼 NOT 👏🏼 deconditioning
Symptoms associated with effort expenditure in #LongCOVID, #MECFS and other energy limiting illnesses are physiological, not “preferential”
Thanks to @RobWust for this incredible work.
www.medrxiv.org/content/10.1...
Reposted by Tessa Green
PLRC is 5 years old today!!!!
If you are able, please consider donating to help sustain #LongCOVID research when it’s needed most.
bit.ly/plrc-donate 1/
If you are able, please consider donating to help sustain #LongCOVID research when it’s needed most.
bit.ly/plrc-donate 1/
April 17, 2025 at 8:02 PM
PLRC is 5 years old today!!!!
If you are able, please consider donating to help sustain #LongCOVID research when it’s needed most.
bit.ly/plrc-donate 1/
If you are able, please consider donating to help sustain #LongCOVID research when it’s needed most.
bit.ly/plrc-donate 1/
Unnatural way to do math
the gf saw me trying to do math in Notepad this way and was aghast that I wouldn't just use actual pen and paper
but I'm like, idk, if ChatGPT can think in LaTeX, so can I !!!
but I'm like, idk, if ChatGPT can think in LaTeX, so can I !!!
April 25, 2025 at 9:55 PM
Unnatural way to do math
I’m much, much more worried about Boston’s networks of world-leading hospitals than I am about Harvard
Good reporting here. Student paper gets what the bigs have missed. White House is actually threatening to defund all of bostons major hospitals www.thecrimson.com/article/2025...
Trump Admin’s $9 Billion Review of Harvard’s Grants Could Hit Boston’s Hospitals Hardest | News | The Harvard Crimson
The Trump administration’s sweeping federal review of nearly $9 billion in multi-year research funding tied to Harvard has sparked uncertainty across the University — but the brunt of the planned cuts...
www.thecrimson.com
April 15, 2025 at 6:23 PM
I’m much, much more worried about Boston’s networks of world-leading hospitals than I am about Harvard
Reposted by Tessa Green
MIT following Harvard's lead here
April 15, 2025 at 1:07 AM
MIT following Harvard's lead here
Reposted by Tessa Green
"Where law ends, tyranny begins."
The president can't just demand $9 billion from Harvard because he feels like it.
If we let power go unchecked, it won’t stop asking. It’ll keep taking. Again and again.
The president can't just demand $9 billion from Harvard because he feels like it.
If we let power go unchecked, it won’t stop asking. It’ll keep taking. Again and again.
April 10, 2025 at 6:23 PM
"Where law ends, tyranny begins."
The president can't just demand $9 billion from Harvard because he feels like it.
If we let power go unchecked, it won’t stop asking. It’ll keep taking. Again and again.
The president can't just demand $9 billion from Harvard because he feels like it.
If we let power go unchecked, it won’t stop asking. It’ll keep taking. Again and again.
Reposted by Tessa Green
Harvard is facing an existential crisis. The Trump administration is blackmailing them and need a community that's willing to stand with them and that's willing to fight.
This is a battle for the soul of Harvard.
Sign and show up this Saturday noon at Cambridge Common
forms.gle/CfFYKjtHBKKV...
This is a battle for the soul of Harvard.
Sign and show up this Saturday noon at Cambridge Common
forms.gle/CfFYKjtHBKKV...
April 9, 2025 at 3:10 PM
Harvard is facing an existential crisis. The Trump administration is blackmailing them and need a community that's willing to stand with them and that's willing to fight.
This is a battle for the soul of Harvard.
Sign and show up this Saturday noon at Cambridge Common
forms.gle/CfFYKjtHBKKV...
This is a battle for the soul of Harvard.
Sign and show up this Saturday noon at Cambridge Common
forms.gle/CfFYKjtHBKKV...
Reposted by Tessa Green
Urgent: The Harvard board flew to Cambridge weekend presumably to decide if they’ll capitulate to Trump. Working on a full-throated response.
Anyone willing to help connect with / organize Harvard faculty, students or others interested in an impromptu demonstration this Saturday?
Anyone willing to help connect with / organize Harvard faculty, students or others interested in an impromptu demonstration this Saturday?
April 8, 2025 at 4:48 PM
Urgent: The Harvard board flew to Cambridge weekend presumably to decide if they’ll capitulate to Trump. Working on a full-throated response.
Anyone willing to help connect with / organize Harvard faculty, students or others interested in an impromptu demonstration this Saturday?
Anyone willing to help connect with / organize Harvard faculty, students or others interested in an impromptu demonstration this Saturday?
Reposted by Tessa Green
gf: "ooh let's try this new chatgpt trend thing"
chatgpt (homophobic): "and they were just friends!"
chatgpt (homophobic): "and they were just friends!"
March 26, 2025 at 11:30 PM
gf: "ooh let's try this new chatgpt trend thing"
chatgpt (homophobic): "and they were just friends!"
chatgpt (homophobic): "and they were just friends!"
Reposted by Tessa Green
Join us! Science Homecoming helps scientists reconnect with communities by writing about the importance of science funding in their hometown newspapers. We’ve mapped every small newspaper in the U.S. and provide resources to get you started. Help science get back home 🧪🔬🧬 🏠
sciencehomecoming.com
sciencehomecoming.com
Science Homecoming
sciencehomecoming.com
February 18, 2025 at 5:12 PM
Join us! Science Homecoming helps scientists reconnect with communities by writing about the importance of science funding in their hometown newspapers. We’ve mapped every small newspaper in the U.S. and provide resources to get you started. Help science get back home 🧪🔬🧬 🏠
sciencehomecoming.com
sciencehomecoming.com
Too real 😭
February 21, 2025 at 3:40 PM
Too real 😭
Every time I think I’ve run out of reasons to be horrified by his appointment…
Even the most disturbing RFK Jr. headline always manages to have a detail inside creepier than you could have imagined. I’m sorry, did you just say Black kids should have a chance to get “re-parented”???? Gift link wapo.st/4hW2xGI
February 17, 2025 at 8:04 PM
Every time I think I’ve run out of reasons to be horrified by his appointment…
Good political news right now feels hard to find, but this is huge for our city. Really hoping that this can move the needle.
I can’t believe it - after years of advocacy, exclusionary zoning has ended in Cambridge.
We just passed the single most comprehensive rezoning in the US—legalizing multifamily housing up to 6 stories citywide in a Paris style
Here’s the details 🧵
We just passed the single most comprehensive rezoning in the US—legalizing multifamily housing up to 6 stories citywide in a Paris style
Here’s the details 🧵
February 11, 2025 at 3:23 AM
Good political news right now feels hard to find, but this is huge for our city. Really hoping that this can move the needle.
Reassuring—hope he’s right
New essay on NIH and indirect costs:
goodscience.substack.com/p/indirect-c...
goodscience.substack.com/p/indirect-c...
Indirect Costs at NIH . . .
I wasn’t planning on spending part of a Saturday writing about cost accounting principles and the like, but NIH-world was hit with a doozy of a policy announcement on Friday night:
goodscience.substack.com
February 10, 2025 at 2:49 PM
Reassuring—hope he’s right
Reposted by Tessa Green
PSA: Digging into Chai-1 and found out that it gives different protein-ligand structures & confidences depending on the SMILES canonicalization used
May also be the case with AF3 & Boltz-1, but haven't verified
As to what this means... see the rest of the thread 🧵
May also be the case with AF3 & Boltz-1, but haven't verified
As to what this means... see the rest of the thread 🧵
February 4, 2025 at 8:38 PM
PSA: Digging into Chai-1 and found out that it gives different protein-ligand structures & confidences depending on the SMILES canonicalization used
May also be the case with AF3 & Boltz-1, but haven't verified
As to what this means... see the rest of the thread 🧵
May also be the case with AF3 & Boltz-1, but haven't verified
As to what this means... see the rest of the thread 🧵
I feel like I’m back in the spring of 2020, bargaining with myself that I can check the news again if I just edit two more sub-aims of this grant application. Except in 2020 I was reasonably confident that the grant organizations would still exist at the point of the deadlines.
February 3, 2025 at 4:12 PM
I feel like I’m back in the spring of 2020, bargaining with myself that I can check the news again if I just edit two more sub-aims of this grant application. Except in 2020 I was reasonably confident that the grant organizations would still exist at the point of the deadlines.
Reposted by Tessa Green
As someone who has reported on AI for 7 years and covered China tech as well, I think the biggest lesson to be drawn from DeepSeek is the huge cracks it illustrates with the current dominant paradigm of AI development. A long thread. 1/
January 27, 2025 at 2:12 PM
As someone who has reported on AI for 7 years and covered China tech as well, I think the biggest lesson to be drawn from DeepSeek is the huge cracks it illustrates with the current dominant paradigm of AI development. A long thread. 1/
I'm not sure if Boston just had another earthquake or the hundred year old house I live in is spontaneously shaking. Both options feel equally plausible.
January 27, 2025 at 3:25 PM
I'm not sure if Boston just had another earthquake or the hundred year old house I live in is spontaneously shaking. Both options feel equally plausible.
Reposted by Tessa Green
Modern GWAS can identify 1000s of significant hits but it can be hard to turn this into biological insight. What key cellular functions link genetic variation to disease?
I'm very excited to present our new work combining associations and Perturb-seq to build interpretable causal graphs! A 🧵
I'm very excited to present our new work combining associations and Perturb-seq to build interpretable causal graphs! A 🧵
January 26, 2025 at 12:13 AM
Modern GWAS can identify 1000s of significant hits but it can be hard to turn this into biological insight. What key cellular functions link genetic variation to disease?
I'm very excited to present our new work combining associations and Perturb-seq to build interpretable causal graphs! A 🧵
I'm very excited to present our new work combining associations and Perturb-seq to build interpretable causal graphs! A 🧵
Me: oh is Chanda into immunology now? Is Tuvix a drug or the name of a biotech
Janeway murdered Tuvix
January 23, 2025 at 4:15 AM
Me: oh is Chanda into immunology now? Is Tuvix a drug or the name of a biotech