Ainoa Guinart
@ainoaguinart.bsky.social
77 followers 180 following 8 posts
PhD candidate @FeringaLab (Groningen, Netherlands) Biomolecular machines 🧪⚡️ in soft materials 👩🏻‍🔬. I also love cats 🐱 and microscopes 🔬
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ainoaguinart.bsky.social
4/🙌This project was a journey through chemistry, membrane biophysics, and light-activated systems. Huge thanks to everyone involved—especially my lab warrior Yusuf Qutbuddin!
ainoaguinart.bsky.social
3/ Why is this study special? 🧪
*Not all motors behave the same!
*We show that system-specific characterization is essential in biological setups.
*Molecular structure and polarity drastically affect motor distribution & membrane interaction (fluidity, tension...)
ainoaguinart.bsky.social
2/ Together with our colleagues from the Schwille Lab, we explored how light-driven rotary molecular motors behave when embedded in lipid membranes. A crucial step toward future responsive biological and biomimetic systems. 🚗🦜
ainoaguinart.bsky.social
👩‍🔬Our new paper is out in Chem! @feringalab.bsky.social We unveil how light-driven rotary motors behave in lipid membranes—and why system-specific characterization is crucial.

Structure & polarity shape membrane interaction and function. Read (or see comments): doi.org/10.1016/j.ch...
Redirecting
doi.org
ainoaguinart.bsky.social
Do you want to see how attaching a light-driven 💡molecular motor 💡 can enhance the 🧫cellular uptake 🧫 of a therapeutic peptide 🏥?

Celebrating woman in science with our latest publication with the VicentPTlab! 👩‍⚕️👩‍⚕️👩‍⚕️

@feringalab.bsky.social

pubs.rsc.org/en/content/a...
A light-driven molecular motor-polypeptide conjugate supports controlled cell uptake
While light-driven molecular motors (MMs) hold immense potential to control cell function, low biocompatibility and solubility have hampered their implementation. We developed a novel polypeptide-conj...
pubs.rsc.org
ainoaguinart.bsky.social
Check out this amazing ScienceSlam about our recent project at the FeringaLab. doi.org/10.1002/adma...

We explore how synthetic molecular machines interact with lipid membranes, triggering crazy shape transformations

Great example how research is not only done in the lab!

youtu.be/S7WKGf_idTE?...
Science Slam of the Munich Clusters of Excellence: Controlling cellular membranes with tiny motors
YouTube video by ORIGINS Cluster
youtu.be