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Andrey Klymchenko @aklymchenko.bsky.social · 19d

Not yet, but we work on that.

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Andrey Klymchenko @aklymchenko.bsky.social · 20d

Thanks, it is rather for point of care applications, where one needs simple, fast, and inexpensive methods.

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Andrey Klymchenko @aklymchenko.bsky.social · Sep 1

Just out in Nanoscale: we found cooperative effects in DNA-functionalized polymeric nanoparticles, important for biosensing & diagnostics. Congrats & thanks to Paraskevi Gaki & startup BrightSens Diagnostics. @unistra.fr, @cnrs.fr, @bpifrance-officiel.bsky.social, #iLab
pubs.rsc.org/en/content/a...

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Andrey Klymchenko @aklymchenko.bsky.social · Aug 18

We acknowledge the support from @agencerecherche.bsky.social, @erc.europa.eu , EIC FastComet, ITI SysChem, @unistra.fr, @cnrs.fr @cnrs-alsace.bsky.social. We thank all our colleagues who contributed to the research mentioned in this review!

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Andrey Klymchenko @aklymchenko.bsky.social · Aug 18

Our review on light-harvesting nanomaterials for energy transfer & biosensing is out in Adv Mater! We analyzed literature on optical materials mimicking nature – chlorophyll in plants. Thanks & congrats to co-authors: Deep Biswas & Pascal Didier!
advanced.onlinelibrary.wiley.com/doi/full/10....

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Reposted by Andrey Klymchenko

Gasser Group @gassergroup.bsky.social · Jul 24

Ready to fly back with @aklymchenko.bsky.social to Paris! Thanks to @faseborg.bsky.social and the organisers for the fantastic event!

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Andrey Klymchenko @aklymchenko.bsky.social · Jun 17

Thanks Erdinc! I am also looking forward to starting this journey!

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Andrey Klymchenko @aklymchenko.bsky.social · Jun 17

Great news: I received ERC Advanced grant #ERCAdG @erc.europa.eu CaptuRel! It aims at intelligent nanomaterials undergoing bioinspired cycle of capture and photorelease of bioactive molecules for sensing and controlling (bio)chemical gradients. Thanks to my Team, @cnrs.fr and @unistra.fr!

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Reposted by Andrey Klymchenko

LabMINT @labmint.bsky.social · Jun 12

Today it is the MINT Day! A good occasion to share science and good moments together. We are really happy to welcome @aklymchenko.bsky.social to open this beautiful day! Thank you very much again for coming ☺️.

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Andrey Klymchenko @aklymchenko.bsky.social · May 28

It was a great experience to participate in JCS2025 conference on supramolecular chemistry. Thanks @iwonanieren.bsky.social et al for the invitation and organization of this wonderful event!

Iwona Nierengarten @iwonanieren.bsky.social · May 26

Great plenary lecture of Andrey KLYMCHENKO @aklymchenko.bsky.social during the JCS2025 in Strasbourg @suprascf.bsky.social @unistra.fr

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Andrey Klymchenko @aklymchenko.bsky.social · May 8

Bürgenstock Conference by @swisschemistry.bsky.social was a truly amazing meeting with brilliant lectures and leading researchers in chemistry: @klanglab.bsky.social, JL Mascarenas, R Buller, @olallalab.bsky.social, D Hilvert, etc. It was an honor to present our work. A big thank to the organizers!

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Andrey Klymchenko @aklymchenko.bsky.social · Apr 29

We thank our collaborator Arnaud Gautier and his team from @sorbonne-universite.fr for the precious contribution.

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Andrey Klymchenko @aklymchenko.bsky.social · Apr 29

New preprint: we introduce peptide-functionalized fluorescent polymeric nanoparticles with stealth properties due to rather short polysarcosine peptides for targeting proteins on cell surface. Congrats to co-authors! @cnrs.fr @unistra.fr @agencerecherche.bsky.social
www.biorxiv.org/content/10.1...

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Andrey Klymchenko @aklymchenko.bsky.social · Apr 14

We thank our collaborators Igor Khalin, Severin Filser and Nikolaus Plesnila @lmumuenchen.bsky.social for their precious contribution to in vivo imaging.

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Andrey Klymchenko @aklymchenko.bsky.social · Apr 14

We revisited our #MemBright toolbox and report anionic cyanine membrane probes with improved properties that enable in vivo imaging of neurons in mice brain. Congrats & thanks to co-authors! Just out Anal. Chem. @acs.org :
pubs.acs.org/doi/10.1021/...
@cnrs.fr @unistra.fr @lmumuenchen.bsky.social

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Andrey Klymchenko @aklymchenko.bsky.social · Apr 11

New preprint alert: we found cooperative effects in DNA-functionalized polymeric nanoparticles, important for biosensing and diagnostics applications. Congrats and thanks to co-author Paraskevi Gaki.
@unistra.fr, @cnrs.fr, @bpifrance-officiel.bsky.social, #BrightSens
www.biorxiv.org/content/10.1...

Cooperative effects in DNA-functionalized polymeric nanoparticles

DNA-functionalized nanoparticles (NPs), called as spherical nucleic acids (SNA), attract strong attention due to their unique properties and numerous applications. In particular, DNA-functionalized dy...

www.biorxiv.org

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Andrey Klymchenko @aklymchenko.bsky.social · Apr 7

Link to the article: onlinelibrary.wiley.com/doi/full/10....
Link to the cover: onlinelibrary.wiley.com/doi/10.1002/...

Fluorescent Artificial Receptor for Dopamine based on Molecular Recognition‐driven Dynamic Covalent Chemistry in a Lipid Nanoreactor

A dynamic artificial receptor is introduced that synergically combines molecular recognition with dynamic imine bond formation inside a lipid nanoreactor, triggering a fluorescence ratiometric respon....

onlinelibrary.wiley.com

Andrey Klymchenko @aklymchenko.bsky.social · Apr 7

The cover (frontispiece) for our recent article on artificial receptor for neurotransmitter dopamine is finally out in @angewandtechemie.bsky.social. Thanks to Jurga Valanciunaite for the artwork!
Congratulations and thanks to the co-authors! @unistra.fr @cnrs.fr @agencerecherche.bsky.social

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Reposted by Andrey Klymchenko

CBM CNRS UPR4301 @cbm-upr4301.bsky.social · Mar 22

Packed room yesterday for a wonderful seminar from @aklymchenko.bsky.social from @cnrs.fr @unistra.fr #Fluorescence for #biomembranes #lipids #proteins
cbm.cnrs-orleans.fr/wp-content/u...

cbm.cnrs-orleans.fr

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Andrey Klymchenko @aklymchenko.bsky.social · Mar 2

No, as I know, it was not recorded.

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Andrey Klymchenko @aklymchenko.bsky.social · Feb 28

A deep dive into magic of biomembrane organization thanks to brilliant talk by @leventallab.bsky.social at PSL Chemical Biology meeting in Paris, @institutcurie.bsky.social, @cnrs.fr

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Andrey Klymchenko @aklymchenko.bsky.social · Feb 20

We thank @cnrs.fr for highlighting our work on the artificial receptor for dopamine, recently published in @angewandtechemie.bsky.social, in their news portal:
www.insb.cnrs.fr/fr/cnrsinfo/...

@cnrsbiologie.bsky.social @unistra.fr @cnrs-alsace.bsky.social

Vers une détection ciblée des neurotransmetteurs : un récepteur artificiel pour la dopamine

Les neurotransmetteurs ont un rôle clé dans le fonctionnement du cerveau et peuvent servir de biomarqueurs pour de nombreuses maladies neurologiques.

www.insb.cnrs.fr

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Reposted by Andrey Klymchenko

Erdinc Sezgin @sciezgin.bsky.social · Feb 19

New paper out 🎇
It has been 13 years since @owenlabuob.bsky.social and co. published a stellar protocol on how to measure membrane order with smart probes! Since then, there has been new dyes, imaging modes and biology! We wrote a protocol for Nature Protocols:
www.nature.com/articles/s41...

Measuring plasma membrane fluidity using confocal microscopy - Nature Protocols

Membrane fluidity is a crucial feature in understanding cellular physiology. This protocol describes a robust pipeline for measuring plasma membrane fluidity using confocal imaging and new environment...

www.nature.com

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Andrey Klymchenko @aklymchenko.bsky.social · Feb 14

Thank you!

Andrey Klymchenko @aklymchenko.bsky.social · Feb 14

It can be used for long-term cell tracking, co-culture of multiple cell populations, cell barcoading, magnetic cell manipulation, etc.

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