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amy-lock.bsky.social
Amy Lock
@amy-lock.bsky.social
82 followers 130 following 4 posts
Postdoctoral researcher in Denk lab and Shaw lab. Researching aberrant sensations in keloid scars. stromal cells | single cell sequencing | iPSC sensory neurons | clinical & translational | pain & itch
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amy-lock.bsky.social
Amy Lock @amy-lock.bsky.social · Aug 20
Happy to announce our preprint going live on BioRxiv! Interested in what’s happening to your fibroblasts’ transcriptomic phenotype once it’s in culture? Look no further!

www.biorxiv.org/content/10.1...

@denklab.bsky.social
#fibroblast #scRNAseq #culture #invitro #keloid #ECM #matrix #mesenchymal
Single-cell RNA sequencing clarifies dermal fibroblast subset representation in vitro and reveals variable persistence of keloid disease-associated features
In vitro models of scarring and fibrosis are essential to improve our understanding of disease mechanisms and ultimately develop much-needed effective therapeutic strategies. This is particularly true...
www.biorxiv.org
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amy-lock.bsky.social
Amy Lock @amy-lock.bsky.social · Apr 18
Hi everyone! I’m seeking a new role and would appreciate your support. If you hear of any opportunities, please send me a message! #OpenToWork

About me:
💼 I’m looking for Postdoctoral/Senior Scientist roles.
🌍 London.
⭐ currently work in fibrosis/scarring/pain/itch
⏰ previously worked in biotech
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amy-lock.bsky.social
Amy Lock @amy-lock.bsky.social · Mar 7
#FluorescenceFriday testing an ATF3 antibody on newly replated immature iPSC-derived sensory neurons. Never get bored of these beautiful images 😍 @denklab.bsky.social
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amy-lock.bsky.social
Amy Lock @amy-lock.bsky.social · Jan 24
#FluorescenceFriday finally got some keloid scar sections to beautifully show their stromal and sensory neuron architecture! Green = FAP (fibroblasts), white = CD31 (endothelial cells), red = b3-tubulin, blue = DAPI.
@denklab.bsky.social
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