Biologic Models
@biologicmodels.bsky.social
86 followers 70 following 230 posts
Makers of custom 3d printed protein models and Mechanism-of-Action 3D animations
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biologicmodels.bsky.social
Here are two glutamate receptors mounted inside a plasma membrane. Combining both receptors in the transparent membrane allows viewers to see the full length of the receptors while also displaying the them vertically. Submit a #3DPrint request at buff.ly/8x5f0BS
biologicmodels.bsky.social
Do you have a colleague who just finished a major accomplishment and you'd like to commemorate their successes? 3D printed protein models with commemorative bases recognize your colleague's accomplishments in molecular biology. Submit a 3D print request at buff.ly/8x5f0BS
biologicmodels.bsky.social
Human Fibroblast Activation Protein Alpha is a serine protease overexpressed in cancer. This #3Dprint commemorates the accomplishments of researchers at the University of Iowa. Celebrate the work of a colleague with a 3D printed protein model buff.ly/8x5f0BS
biologicmodels.bsky.social
Human Cytomegalovirus HCMV infection is regulated by Glycoprotein B (gB) making it a target for neutralizing antibodies and a vaccine candidates. This 3D printed model of #HCMV Glycoprotein B visualizes where neutralizing antibodies bind the glycoprotein. buff.ly/9hXrp6F
biologicmodels.bsky.social
Phosphate-binding Protein exhibits a large increase in fluorescence on binding inorganic phosphate due to the structural changes of the protein. This #3DPrint is colored Blue-to-Red from N-to-C Terminal. Submit a request for a custom protein model at buff.ly/AH5fMuj
biologicmodels.bsky.social
RsmA-CsrA proteins are translational inhibitors in many bacterial species. This #3DPrint of a RsmA-CsrA RNA Complex 2JPP reveals the blocked ribosome-binding site of the hcnA gene. Have a protein dataset you'd like to 3D print? Submit a request at buff.ly/490PgIJ
biologicmodels.bsky.social
3D Printed models of proteins created from x-ray crystallography data sets. Hand-held scientific models of proteins bridge the scientific gap between the digital and physical world. #3DPrint your own protein model at buff.ly/d5ZDAWZ
biologicmodels.bsky.social
Lots of cusotmers want to demonstrate how proteins interact or demonstrate where small molecules bind to target proteins. Do you have a similar #biotech #sciencecommunication needs, send us a #3Dprint request to at buff.ly/490PgIJ
biologicmodels.bsky.social
This is a #3DPrint of Adeno-associated Virus (AAV-2) 1LP3, a vector delivery system for human gene therapy. It is being used to treat diseases including hemophilia, cancer, and cystic fibrosis. buff.ly/kprjOpH
biologicmodels.bsky.social
Our #3Dprint of the #SARS-CoV2 Virion is used by doctors to explain the importance of blood glucose control during infections by pointing to the way sugar molecules (green) bind to the Spike protein (yellow) which hides the virus from immune detection. buff.ly/3AdFpko
biologicmodels.bsky.social
RsmA-CsrA proteins are translational inhibitors in many bacterial species. This #3DPrint of a RsmA-CsrA RNA Complex 2JPP reveals the blocked ribosome-binding site of the hcnA gene. Have a protein dataset you'd like to 3D print? Submit a request at buff.ly/9hXrp6F
biologicmodels.bsky.social
Human Fibroblast Activation Protein Alpha is a serine protease overexpressed in cancer. This #3Dprint commemorates the accomplishments of researchers at the University of Iowa. Celebrate the work of a colleague with a 3D printed protein model buff.ly/9hXrp6F
biologicmodels.bsky.social
More hybrid models shipping to #Europe this week. These protein models utilize a glass-like transparent surface and an opaque ribbon or ball-and-stick interior to visualize structures deep inside proteins. Submit a #3Dprint request for a Hybrid model at buff.ly/9hXrp6F
biologicmodels.bsky.social
While deadly and pathologic, viruses are amazing macromoleucular machines. 3D printed scientific models of viruses visualize the structural complexity and mathematics behind capsid formation. Want to create your own virus model? Submit a #3Dprint request @ buff.ly/9hXrp6F
biologicmodels.bsky.social
This is a 3D print of SerRS-tRNASec complex. It displays the first step in selenocysteine biosynthesis. tRNA is colored by nucleotide and the SerRS is color Blue-to-Red from N to C terminal. Submit a #3Dprint request for a custom 3D-printed protein model. buff.ly/8IZNAS7
biologicmodels.bsky.social
Ribbon protein models make for amazing toy-like scientific models, and beautiful large-format works of art meant for display in museums or galleries. They sure can be difficult to #3Dprint. Not a problem for Biologic Models. Submit a #3DPrint request at buff.ly/lqsT0OR
biologicmodels.bsky.social
Love getting emails from customers saying the person who received their protein model really loved their gift. It means a lot to us that we can support scientists. If you have a colleage whose work you'd like to commemorate, submit a #3DPrint request at buff.ly/9hXrp6F
biologicmodels.bsky.social
Despite the Type 2 wild #poliovirus being declared eradicated in 2015, a vaccine-derived mutated version of the virus has reemerged in multiple countries. Explore the protein structure of the Type 2 Poliovirus #3DPrint #virology buff.ly/fel3xep
biologicmodels.bsky.social
Here are two #3Dprints of a monoclonal antibody (blue) and a custom antibody (green) bound to the programmed cell death receptor PD1 (red). Work with one of our visualization scientists to create similar custom 3D printed protein models. buff.ly/lqsT0OR
biologicmodels.bsky.social
StuartHameroff and Roger Penrose suggest networks of tryptophan residues are critical for consciousness. In this #3DPrint of Microtubule 3J2U, we can see how Tryptophan residues interconnect alpha and beta chains of adjacent tubulin molecules.
buff.ly/BJwy7x4
biologicmodels.bsky.social
Do it! It would look amazing
biologicmodels.bsky.social
Retroviral capsid proteins are conserved structurally but assemble differently. The mature #HIV capsid is described by as a 'fullerene cone' in which hexamers of the capsid are linked to form a hexagonal surface capped by a 12 capsid-protein pentamers. buff.ly/wG32YDy
biologicmodels.bsky.social
This protein was created by Alphafold, which can be notoriously difficult to 3d print. Blue regions are confidently folded, yellow and orange regions have decreasing confidence. If you need help printing an alphafold protein, send us a #3DPrint request at buff.ly/u0ml0cB
biologicmodels.bsky.social
I love how these hybrid models turn out. This is a 3D print of Neutralizing Nanobodies bound to the #SARS-CoV2 #Spike Glycoprotein #Omicron variant. This hybrid #3DPrint combines the ribbon interior with its volumetric surface. Sumbit a 3D print request at buff.ly/u0ml0cB
biologicmodels.bsky.social
The Nuclear Pore Complex is one of the largest protein complexes. Its architecture is dynamic. Changes in envelope tension manifest conforma­tional breathing during dilation and constriction movements. Submit a 3D print request for a macromolecule like NPC buff.ly/Jw5Pa1v