Information about Listeria outbreak linked to prepared meals.

Use of primary oral vancomycin prophylaxis to stem an outbreak of Clostridioides difficile infection in intensive care patients - Volume 5 Issue 1

Healthcare-associated infections compromise patient outcomes and pose a burden on healthcare systems worldwide. Despite widespread awareness of the critical role of Hand Hygiene (HH) in preventing healthcare-associated infections, compliance among healthcare workers remains suboptimal. This study evaluates a reward program called the Hero Program which is designed to incentivize and sustain HH practices through positive reinforcement.

Abstract. In outpatient parenteral antimicrobial therapy, weekly lab monitoring is often standard practice, even for antimicrobials with low complication r

Check out the top 5 infection control and prevention articles for Summer 2025! Perennial articles like Bug of the Month and The Clean Bite, and a look at borescopes in sterile processing.

Understand the FDA's role in laboratory developed tests as oversight transitions back to CLIA for better lab regulation clarity.

Explore the importance of standardized Genomic Reports and how they enhance clinical decision-making with clear insights.

Candidozyma auris, formerly referred to as Candida auris, has been identified as a swiftly spreading drug-resistant fungus posing a significant risk to individuals with compromised immune systems. Its ability to cause severe illnesses and even death is causing alarm in the healthcare sphere, particularly as its transmission continues to increase and outbreaks ramp up

The appropriate duration of anticoagulation for venous thromboembolism (VTE) in patients who have a transient provoking factor (e.g., surgery, trauma, or immobility) and concomitant enduring risk f...

Patients with hematologic malignancies and hematopoietic stem cell transplant recipients (HSCT) are at high risk of central venous catheter-related bloodstream infections (CLABSI). Global actions have encouraged patient empowerment as a strategy to reduce these infections. We aim to evaluate the impact of patient empowerment in reducing the incidence density (ID) of CLABSI.

In this second-ever collaboration between SIDP’s Breakpoints and ESCMID’s Communicable podcasts, hosts Erin McCreary and Angela Huttner invite the two

Researchers are establishing standards to validate the efficacy of AI agents in clinical settings.

Outcomes in patients with untreated versus treated asymptomatic bacteriuria within five Veterans Affairs facilities

Managing Back-to-School Respiratory Infections In late summer, tens of millions of children throughout the United States return to school, sharing tales of their summer adventures and, inevitably, new germs. Many will develop a cough, sore throat, or runny nose in the coming weeks, as part of a well-documented “summer wave” of respiratory infections.  In 2025, […]

A urinalysis to urine culture reflex protocol results in high rates of asymptomatic bacteriuria treatment - Volume 5 Issue 1

Information about an outbreak of Salmonella linked to home delivery meals.

Background Hemodialysis-associated bloodstream infections (BSIs) represent a significant burden for patients. Understanding the trends in BSIs among hemodialysis patients is crucial for informing strategies to reduce their incidence and improve patient outcomes. This study aimed to evaluate secular trends, identify causative organisms, assess resistance patterns, and determine the sources of hemodialysis-associated BSIs at Geneva University Hospitals, where Staphylococcus aureus screening and decolonization of hemodialysis patients have been implemented since the year 2000. Methods A longitudinal cohort study was conducted using data from 2006 to 23. We included all patients receiving maintenance hemodialysis treatment at our institution. A hemodialysis-associated BSI was defined as BSI occurring during active hemodialysis treatment and diagnosed either during hospital admission or in outpatient hemodialysis unit. Outcomes included incidence rates of hemodialysis-associated BSIs, trends in causative pathogens, sources, and resistant organisms. Poisson regression was used to model trends over time of incidence rate ratios (IRR). Results A total of 313 true BSI episodes were identified in 218 hemodialysis patients over 11,413 patient-hemodialysis months. The overall BSI incidence rate was 2.7 episodes per 100 patient-hemodialysis-months, with a consistent decrease over time. Compared to 2006-08, hemodialysis-associated BSI rates decreased by 16% in 2009-11 (IRR 0.84, 95% confidence interval [CI] 0.60–1.18), and by a maximum of 44% in 2021-23 (IRR 0.56, 95% CI 0.36–0.83). The decreasing trend was mainly due to reduced S. aureus BSIs, while Enterobacterales BSIs rates remained stable. Catheter-related BSIs accounted for 41.5% of infections (130/313), with marked reduction following 2014. BSIs caused by resistant bacteria were rare, with decreasing trends of methicillin-resistant S. aureus. Conclusions Hemodialysis-associated BSI rates significantly declined, driven largely by reductions in S. aureus BSIs and catheter-related infections. No replacement by Gram-negative BSI was observed. Prevention of hemodialysis-associated BSI is key for reducing infection burden among hemodialysis patients.

Short-course intravenous beta-lactams for uncomplicated cystitis in hospitalized patients - Volume 5 Issue 1

Healthcare-associated infections (HAIs) are common adverse events, and surveillance is considered a core component of effective HAI reduction programmes. Recently, efforts have focused on automating ...

npj Antimicrobials and Resistance - The effect of commonly used non-antibiotic medications on antimicrobial resistance development in Escherichia coli

Explore PGx variants and their role in pharmacogenomics. Learn how genomic reports translate data into clinical insights.