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Luca Braccioli Lab @ UU @bracciolilab.bsky.social · 14d

Congratulations Luca and the rest of the team, exciting story!

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Luca Braccioli Lab @ UU @bracciolilab.bsky.social · 17d

Once again super congrats to you, Christine, Bas and the rest of the team!!!

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Reposted by Luca Braccioli Lab @ UU

Bas van Steensel lab (NKI) @basvansteensellab.bsky.social · Sep 2

Very proud of our paper on "scrambling-by-hopping" LADs, which was just published: www.nature.com/articles/s41.... Congrats to Lise Dauban and the rest of the team – this was a real tour-de-force!

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Reposted by Luca Braccioli Lab @ UU

Ryan Savill @cryaaa.bsky.social · 27d

(1/14) I’m happy and proud to introduce: SpinePy – a framework to detect the "spine" of gastruloids and measure biological and physical signals in a local dynamic 3D coordinate system. www.biorxiv.org/content/10.1...

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Luca Braccioli Lab @ UU @bracciolilab.bsky.social · 23d

It was a pleasure reading your work, excited about the next developments!

Luca Braccioli Lab @ UU @bracciolilab.bsky.social · 23d

Big thanks to my PhD student @wesselbrouwer.bsky.social and @dev-journal.bsky.social

Luca Braccioli Lab @ UU @bracciolilab.bsky.social · 23d

Ever wondered how to get a gastruloid to grow a head?

The Bulut-Karslioğlu lab figured out that by growing different stem cell aggregates in high and low oxygen and later assembling them, you can get gastruloids with a fully formed neural tube. Check out our "In preprints": doi.org/10.1242/dev....

In preprints: gastruloids get (a)head

A major breakthrough in the field of mammalian embryology is the development of stem-cell based embryo models. Derived from pluripotent stem cells, such as embryonic stem cells or induced pluripotent ...

doi.org

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Reposted by Luca Braccioli Lab @ UU

Nicoletta Petridou @nicolettapetridou.bsky.social · Aug 8

We are searching for an enthusiastic scientist to join our team and establish annual killifish as a model system for early developmental biology and biophysics! @embl.org @embldbunit.bsky.social

Apply here:
embl.wd103.myworkdayjobs.com/EMBL/job/Hei...

Please re-post 🙏

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Reposted by Luca Braccioli Lab @ UU

Elphege Nora Lab at UCSF @elphegenoralab.bsky.social · Aug 16

New preprint with @gfudenberg.bsky.social

We find the rate of cohesin loop extrusion in cells is set by NIPBL dosage and tunes many aspects of chromosome folding.

This provides a molecular basis for NIPBL haploinsufficiency in humans. 🧵👇

www.biorxiv.org/content/10.1...

NIPBL dosage shapes genome folding by tuning the rate of cohesin loop extrusion

Cohesin loop extrusion is a major driver of chromosome folding, but how its dynamics are controlled to shape the genome remains elusive. Here we disentangle the contributions of the cohesin cofactors ...

www.biorxiv.org

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Reposted by Luca Braccioli Lab @ UU

Hanneke Vlaming @hannekevlaming.bsky.social · Aug 15

The Vlaming lab is expanding! If you are or know a good prospective PhD student, excited about studying transcription, please (suggest them to) apply here: www.uu.nl/en/organisat...
My biased opinion: exciting topic, super nice colleagues, and great research environment in a lovely city.

PhD position in Gene Regulation

Are you excited about studying the crucial process of transcription? Join our supportive, young and growing team!

www.uu.nl

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Reposted by Luca Braccioli Lab @ UU

Alfonso Martinez Arias @amartinezarias.bsky.social · Jul 15

Two new preprints from the @arjunraj.bsky.social‬ on #gastruloids. Both excellent. Exploring the relationship between macroscopic reproducibility v microscopic heterogeneity. Stunning experiments and much to think about
biorxiv.org/content/earl...
biorxiv.org/content/earl...

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Reposted by Luca Braccioli Lab @ UU

Ina Sonnen @sonnenlab.bsky.social · Jul 10

Please pread the word.

We have just launched the Hubrecht International PhD Program (HIPP).

Are you looking for a PhD position in molecular and developmental biology or related subject in an international, very supportive and collaborative environment?

Then apply to the HIPP!! 👇

Hubrecht Institute @hubrechtinstitute.bsky.social · Jul 10

🧬 Looking for a PhD position in molecular or developmental biology? 🔬

✉️ The Hubrecht Institute now has its very own PhD program! Applications are open and will be accepted until September 15th. Read more here 👉 www.hubrecht.eu/hipp/

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Luca Braccioli Lab @ UU @bracciolilab.bsky.social · Jul 10

Congratulations Adriano!!!

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Reposted by Luca Braccioli Lab @ UU

Alfonso Martinez Arias @amartinezarias.bsky.social · Jun 23

Excellent work supporting #modularity of the mammalian #embryo, a role for #hypoxia & how development exploits these features. It shows what we can learn from assemblies of #gastruloids @ spatio-temporal coordination of the modules in AP organization. Putting modules together, extremely informative

Aydan Bulut-Karslioglu @bulutkarslioglu.bsky.social · Jun 23

⚠️ I am really excited to share the work of Anastasios Balaskas, an excellent PhD candidate in the lab, with the wider world. Tasos made a significant advance: generating a stem cell-based embryo model that contains both posterior and anterior neural tissues of the late-stage gastrulating embryo.

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Reposted by Luca Braccioli Lab @ UU

Jacob (Yaqub) Hanna - يعقوب حنا @jacob-hanna.bsky.social · Jun 23

Fantastic work from @bulutkarslioglu.bsky.social group. we r happy to contribute on the role of hypoxia in proper gastrulation ex utero as originally noted in Aguilera-Castrejon et al. Nature 2021 for robust gastrulation. Now this is shown to be important for taking gastruloids to the next level.

Aydan Bulut-Karslioglu @bulutkarslioglu.bsky.social · Jun 23

⚠️ I am really excited to share the work of Anastasios Balaskas, an excellent PhD candidate in the lab, with the wider world. Tasos made a significant advance: generating a stem cell-based embryo model that contains both posterior and anterior neural tissues of the late-stage gastrulating embryo.

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Luca Braccioli Lab @ UU @bracciolilab.bsky.social · Jun 24

Congratulations Aydan, Tasos and the rest of the team for this beautiful work!

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Reposted by Luca Braccioli Lab @ UU

Aydan Bulut-Karslioglu @bulutkarslioglu.bsky.social · Jun 23

⚠️ I am really excited to share the work of Anastasios Balaskas, an excellent PhD candidate in the lab, with the wider world. Tasos made a significant advance: generating a stem cell-based embryo model that contains both posterior and anterior neural tissues of the late-stage gastrulating embryo.

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Luca Braccioli Lab @ UU @bracciolilab.bsky.social · Apr 26

More have been found: www.bbc.com/news/article...

Luca Braccioli Lab @ UU @bracciolilab.bsky.social · Apr 17

Congratulations Kristina, Vikas and the rest of the team!

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Reposted by Luca Braccioli Lab @ UU

Kristina Stapornwongkul @kstapornwongkul.bsky.social · Apr 16

📢 Fresh off the press and featuring new exciting experiments! 🧪
We show how glycolytic activity instructs germ layer proportions through regulation of Nodal and Wnt signaling - happy to finally share this 😊
doi.org/10.1016/j.st...

B2B with @jesseveenvliet.bsky.social lab: doi.org/10.1016/j.st... 🤩

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Luca Braccioli Lab @ UU @bracciolilab.bsky.social · Apr 17

Congratulations to the whole team!

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Reposted by Luca Braccioli Lab @ UU

Kristina Stapornwongkul @kstapornwongkul.bsky.social · Apr 14

🚨Just one week left to apply! Join our team @imbavienna.bsky.social!

Kristina Stapornwongkul @kstapornwongkul.bsky.social · Mar 20

Thrilled to announce that I am looking for a Research Technician/Assistant to join my lab @imbavienna.bsky.social. Please consider applying if you’re enthusiastic about #devbio #stemcells #teamwork and excited to help shaping a new lab!

Thankful for any retweet! 🫶

imba.onlyfy.jobs/job/l6u2m980

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Reposted by Luca Braccioli Lab @ UU

Virginia De Andrade @virginiar-andra.bsky.social · Mar 29

Thank you! A special thanks to the organizers for putting this fantastic meeting together @moritzbauer.bsky.social @bracciolilab.bsky.social Hendrik Marks, Susana Chuva de Sousa, Lopes and Niels Geijsen. And to Wilke Meijer and Suzan Stello for working together on this exciting project!!

Ina Sonnen @sonnenlab.bsky.social · Mar 28

Well done @virginiar-andra.bsky.social from our lab for being awarded the Best Poster Prize at the International Dutch Embryo Model Meeting today for our work on “Spatiotemporally resolved omics reveals dynamic antagonistic gradients” in embryo segmentation. Congratulations!

Moritz Bauer @moritzbauer.bsky.social · Dec 3

📢 Save the date! We are excited to announce the International Dutch Embryo Model Meeting 2025 in Nijmegen (NL) on Thursday 27 March and Friday 28 March! Registration is open now. More information: ru.nl/en/about-us/...

Big thanks to Hendrik Marks for taking the lead this time!

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