Lightnews — Scholar-powered news

Chris Bannon @cabannon.bsky.social · Aug 14

x.com/KewinSiah/st...

Re-sharing on here as I don't have X - many thanks for sharing Prof Siah!

Please share across to Gastroenterology groups: our paper identifying gut hormone INSL5 having involvement in bile acid diarrhoea and ibs-d.

Kewin Siah on X: "🔥 study: Insulin-like peptide 5 (INSL5) surges in response to rectal bile acids, linked to urge to defecate & diarrhea severity in bile acid diarrhea (BAD) patients. Elevated in BAD & subset of #IBS-D; predicts better ondansetron response. #Gitwitter https://t.co/CPBztSp6Wv https://t.co/Gysi9uYqrv" / X

🔥 study: Insulin-like peptide 5 (INSL5) surges in response to rectal bile acids, linked to urge to defecate & diarrhea severity in bile acid diarrhea (BAD) patients. Elevated in BAD & subset of #IBS-D; predicts better ondansetron response. #Gitwitter https://t.co/CPBztSp6Wv https://t.co/Gysi9uYqrv

x.com

Chris Bannon @cabannon.bsky.social · Jul 29

Interview on our published paper last week describing how an identified gut hormone is involved in symptoms of patients with chronic diarrhoea:

www.cam.ac.uk/research/new...

Discovery of role of gut hormone in chronic diarrhoea could aid development of new tests and treatments

High levels of a hormone found in cells in the gut could underlie many cases of chronic diarrhoea and help explain up to 40% of cases of patients with

www.cam.ac.uk

2 3

Reposted by Chris Bannon

Richard Kay @richard-kay.bsky.social · Jul 24

And here is the paper on INSL5. LC-MS/MS analysis generated similar concentration data compared to an ELISA. The peptide circulates at 100's of pg/mL in disease state, and almost undetectable in control individuals.

Chris Bannon @cabannon.bsky.social · Jul 24

My project from my PhD has been published in Gut BMJ today!
The paper highlights an understudied gut hormone INSL5 has a role in chronic diarrhoea, in particular bile acid diarrhoea and a subset of patients with IBS.
@richard-kay.bsky.social
@ims-mrl.bsky.social
gut.bmj.com/content/earl...

Insulin-like peptide 5 is released in response to bile acid in the rectum and is associated with diarrhoea severity in patients with bile acid diarrhoea

Background Insulin-like peptide 5 (INSL5) is an enteroendocrine hormone expressed in distal colonic ‘L cells’. Bile acid receptor agonists are known to stimulate INSL5 secretion in primary cell cultur...

gut.bmj.com

1 2

Chris Bannon @cabannon.bsky.social · Jul 24

My project from my PhD has been published in Gut BMJ today!
The paper highlights an understudied gut hormone INSL5 has a role in chronic diarrhoea, in particular bile acid diarrhoea and a subset of patients with IBS.
@richard-kay.bsky.social
@ims-mrl.bsky.social
gut.bmj.com/content/earl...

Insulin-like peptide 5 is released in response to bile acid in the rectum and is associated with diarrhoea severity in patients with bile acid diarrhoea

Background Insulin-like peptide 5 (INSL5) is an enteroendocrine hormone expressed in distal colonic ‘L cells’. Bile acid receptor agonists are known to stimulate INSL5 secretion in primary cell cultur...

gut.bmj.com

1 2

Chris Bannon @cabannon.bsky.social · Apr 7

My interview has been published!
Check it out below where I chat about use of AI and machine learning in healthcare research, and how I use it in my research
www.youtube.com/watch?v=NqKd...

@ims-mrl.bsky.social
@richard-kay.bsky.social
@acceleratescience.bsky.social

Supervised Learning in Healthcare - Dr Chris Bannon

YouTube video by Accelerate Science

www.youtube.com

3

Chris Bannon @cabannon.bsky.social · Dec 11

Being filmed for an interview talking about using AI in clinical research! @acceleratescience.bsky.social @catherinebreslin.bsky.social

4

Chris Bannon @cabannon.bsky.social · Dec 2

Another accelerate course - another tote bag swag.
The best courses for learning AI and the best freebies around.

1

Reposted by Chris Bannon

Richard Kay @richard-kay.bsky.social · Nov 22

Just posted with the #peptidomics tag and there have only been three... Including this one!

We definitely need a Peptidomics list - us peptide MS scientists need to get the field more exposure!!

1 3

Chris Bannon @cabannon.bsky.social · Nov 26

Please can I be added thanks!

1

Chris Bannon @cabannon.bsky.social · Nov 26

Please can I be added to the list. Thanks!

1 1

Chris Bannon @cabannon.bsky.social · Nov 26

Presenting my work on the need for explainable AI models in medicine yesterday at the AI for science summit!

Catherine Breslin @catherinebreslin.bsky.social · Nov 25

Next up at today’s AI for Science summit is Dr Chris Bannon talking about the importance of explainable AI in medicine

2 12

Reposted by Chris Bannon

Catherine Breslin @catherinebreslin.bsky.social · Nov 25

Next up at today’s AI for Science summit is Dr Chris Bannon talking about the importance of explainable AI in medicine

1 8