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carman-mc-li.bsky.social
Carman Li
@carman-mc-li.bsky.social
310 followers 430 following 9 posts
Assistant Professor @UPenn.bsky.social www.CarmanLiLab.org Hereditary cancers, BRCA1/2, mouse models, organoids, single-cell omics
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carman-mc-li.bsky.social
Carman Li @carman-mc-li.bsky.social · Apr 20
Our lab has opened at the Cancer Biology Department and the Basser Center for BRCA @upenn.bsky.social! We study new mechanisms of hereditary cancers and their implications for sporadic cancers, building on my training with @labjacks.bsky.social and Joan Brugge.

Join us! tinyurl.com/CarmanLiLabH...
Carman Li Lab
www.CarmanLiLab.org
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carman-mc-li.bsky.social
Carman Li @carman-mc-li.bsky.social · Jul 12
Thank you Kevin!
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carman-mc-li.bsky.social
Carman Li @carman-mc-li.bsky.social · Jul 1
Our lab welcomed Isabella Cagno earlier this month. She hit the ground running, and we had a great time at the @upenn.bsky.social Cancer Biology annual retreat at beautiful Skytop, PA!
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Carman Li @carman-mc-li.bsky.social · Apr 30
Very happy to share our work at #AACR25! Thank you @theaacr.bsky.social and @bcrfcure.bsky.social for the travel award! It was fun to connect with colleagues @pennmedicine.bsky.social, @harvardmed.bsky.social, and beyond.
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Carman Li @carman-mc-li.bsky.social · Apr 20
Thanks Sunny!
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carman-mc-li.bsky.social
Carman Li @carman-mc-li.bsky.social · Apr 20
Our lab has opened at the Cancer Biology Department and the Basser Center for BRCA @upenn.bsky.social! We study new mechanisms of hereditary cancers and their implications for sporadic cancers, building on my training with @labjacks.bsky.social and Joan Brugge.

Join us! tinyurl.com/CarmanLiLabH...
Carman Li Lab
www.CarmanLiLab.org
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carman-mc-li.bsky.social
Carman Li @carman-mc-li.bsky.social · Nov 26
Thank you!
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Carman Li @carman-mc-li.bsky.social · Nov 26
Thank you Salah!

I'd like to suggest the following additions:
@heidefordlab.bsky.social
@tarumur.bsky.social
@mike-oli.bsky.social
@harrislab.bsky.social
@stoverlab.bsky.social
@zervanto.bsky.social
@madeleineoudin.bsky.social
@drsarapensa.bsky.social
@amulyasreekumar.bsky.social
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Carman Li @carman-mc-li.bsky.social · Nov 25
Thank you for highlighting our work @harvardcellbio.bsky.social!
carman-mc-li.bsky.social
Carman Li @carman-mc-li.bsky.social · Nov 20
Thank you, Camila @caoresco.bsky.social and Steven Lewis, for highlighting our work in this News & Views in Nature Genetics!
caoresco.bsky.social
Camila dos Santos @caoresco.bsky.social · Nov 20
Check out our News and views on @carman-mc-li.bsky.social cool study about the molecular regulation of Brca1 deficiency mammary oncogenesis - with Steven Lewis www.nature.com/articles/s41...
Epigenetic scars of Brca1 loss point toward breast cancer cell of origin - Nature Genetics
The two-hit hypothesis suggests that a second mutation is necessary for cancer development in cells with a defective tumor-suppressor gene, such as BRCA1. However, a study now shows that the loss of j...
www.nature.com
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Reposted by Carman Li
harvardcellbio.bsky.social
Harvard Med Cell Biology @harvardcellbio.bsky.social · Nov 11
New work from Joan Brugge's lab @harvardcellbio.bsky.social explores how Brca1 haploinsufficiency promotes early tumor onset and epigenetic alterations in a mouse model of hereditary breast cancer - Led by Carman Li www.nature.com/articles/s41...
Brca1 haploinsufficiency promotes early tumor onset and epigenetic alterations in a mouse model of hereditary breast cancer - Nature Genetics
A second hit to Brca1 in heterozygous mice leads to accelerated tumor development compared to wild-type mice in which both alleles are simultaneously deleted. This is because of an epigenetic state as...
www.nature.com
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