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Reposted by Cassidy Prince

ASM @asm.org · Sep 3

As national medical, scientific, public health and patient organizations, we call for the resignation of HHS Secretary Robert F. Kennedy Jr. to ensure the health of the American people. Read our statement: asm.org/press-releas...

Joint Statement Calling for Secretary Kennedy Resignation

The American Society for Microbiology released a joint statement calling for the resignation of HHS Secretary Robert F. Kennedy Jr.

asm.org

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Reposted by Cassidy Prince

Heather Feaga @heatherfeaga.bsky.social · Aug 28

Here we show that >90% of Paenibacillus encode a unique Spo0B with a transmembrane domain! TM domain helps it interact with its phosphorelay partners. Congrats to @isabellalin.bsky.social who left for grad school this week and her mentor @cassidyprints.bsky.social! www.biorxiv.org/content/10.1...

Conservation of sporulation genes and a transmembrane-containing Spo0B variant in Paenibacillus

Sporulation is a strategy employed by many bacteria to survive harsh environmental conditions. The genus Paenibacillus includes spore-forming species notorious for spoiling pasteurized dairy products ...

www.biorxiv.org

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Cassidy Prince @cassidyprints.bsky.social · Aug 25

Awesome work from my mentee @isabellalin.bsky.social on sporulation in non-model Bacilli!!

bioRxiv Microbiology @biorxiv-microbiol.bsky.social · Aug 25

Conservation of sporulation genes and a transmembrane-containing Spo0B variant in Paenibacillus https://www.biorxiv.org/content/10.1101/2025.08.24.672004v1

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Reposted by Cassidy Prince

Heather Feaga @heatherfeaga.bsky.social · Aug 19

Latest from the lab! Analysis of everyone’s favorite regulatory mechanism in bacteria — the RF2 programmed frameshift! Likely present in the ancestor of bacteria, use of this mechanism is influenced by stop codon usage! Big congrats to @cassidyprints.bsky.social
journals.asm.org/doi/10.1128/...

Conservation and evolution of the programmed ribosomal frameshift in prfB across the bacterial domain | mBio

Translation termination is catalyzed by one of two release factors in bacteria, RF1 or RF2. It has been known for decades that RF2 levels in Escherichia coli are regulated by a programmed ribosomal frameshift within the prfB gene that encodes RF2. We ...

journals.asm.org

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Cassidy Prince @cassidyprints.bsky.social · Aug 19

Thank you to my amazing advisor @heatherfeaga.bsky.social and incredible mentee @isabellalin.bsky.social for all your help!

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Cassidy Prince @cassidyprints.bsky.social · Aug 19

Just published the first chapter of my thesis! 🥰

E. coli regulates the levels of a translation release factor (RF2) via a *purposeful* frameshift during translation. We found that most other bacteria do this too and it's likely an ancient mechanism!

journals.asm.org/doi/10.1128/...

Conservation and evolution of the programmed ribosomal frameshift in prfB across the bacterial domain | mBio

Translation termination is catalyzed by one of two release factors in bacteria, RF1 or RF2. It has been known for decades that RF2 levels in Escherichia coli are regulated by a programmed ribosomal frameshift within the prfB gene that encodes RF2. We ...

journals.asm.org

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Reposted by Cassidy Prince

Heather Feaga @heatherfeaga.bsky.social · Apr 13

Latest work from the lab - we identify a translation factor, YebC2, that reduces ribosome stalling in B. subtilis!

Congrats to co-first authors: grad students Hye-Rim Hong & Cassidy Prince & undergrad Dennis Wu @denniswu02.bsky.social

journals.plos.org/plosgenetics...

YebC2 resolves ribosome stalling and increases fitness of cells lacking EF-P and the ABCF ATPase YfmR

Author summary Polyproline motifs are essential structural features of many proteins but are difficult for the ribosome to synthesize. EF-P reduces ribosome pausing at polyproline motifs. Here, we sho...

journals.plos.org

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