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challis-group.bsky.social
Challis-Alkhalaf Group
@challis-group.bsky.social
34 followers 81 following 3 posts
Group of scientists at the University of Warwick and Monash University interested in the discovery, biosynthesis, bioengineering, mechanism of action, and translational application of microbial natural products and the enzymes that assemble them
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challis-group.bsky.social
Challis-Alkhalaf Group @challis-group.bsky.social · 3d
Check out the latest version of our preprint on nitrogen deletion in HDAC-targetting anticancer drug biosynthesis. Amazing work by Xinyun Jian @monashuniversity.bsky.social, Jinlian Zhao @uni-of-warwick.bsky.social and colleagues in the Cryle and Fairlie labs.

www.biorxiv.org/content/10.1...
Nitrogen deletion in the biosynthesis of HDAC-targeting anticancer drugs
Small molecules play indispensable roles in living systems as hormones, membrane bilayer constituents, enzyme cofactors, metal chelators, and defensive chemicals. The exceptional structural diversity ...
www.biorxiv.org
challis-group.bsky.social
Challis-Alkhalaf Group @challis-group.bsky.social · 18d
Lona Alkhalaf will speak about the discovery, structure, and mechanism of a cool new family of enzymes discovered by the group at the 29th Enzyme Mechanisms Conference.

www.enzymemechanismsconference.org/speakers
Speakers | emc2026
www.enzymemechanismsconference.org
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challis-group.bsky.social
Challis-Alkhalaf Group @challis-group.bsky.social · 18d
Greg Challis will be presenting the group's latest insights into peptidyl epoxyketone biosynthesis at the 16th Australian Peptide Conference in beautiful Tasmania.

www.peptides2025.org
16th Australian Peptide Conference
www.peptides2025.org
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Reposted by Challis-Alkhalaf Group
niedermeyer-lab.bsky.social
Timo Niedermeyer @niedermeyer-lab.bsky.social · May 22
Interested in natural product producing microorganisms? 🦠 See you in Berlin... 😀
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Reposted by Challis-Alkhalaf Group
ref2029.bsky.social
ref2029.bsky.social @ref2029.bsky.social · Sep 4
The names of panel members for the criteria-setting phase of REF 2029 have now been announced on our panels pages. 2029.ref.ac.uk/news/expert-...
Expert panels appointed for REF 2029  – REF 2029
2029.ref.ac.uk
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Reposted by Challis-Alkhalaf Group
nicolerobb.bsky.social
Nicole Robb @nicolerobb.bsky.social · 20d
Excited to announce our latest preprint, exploring the stereochemistry & antiviral properties of natural product MM46115 (pellemicin) against influenza. 🦠 💊 Big thanks to all co authors, including @afifahtasnim.bsky.social @craigpthomp.bsky.social and others. www.biorxiv.org/content/10.1...
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