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ckajba.bsky.social
Christina Kajba
@ckajba.bsky.social
34 followers 69 following 1 posts
Doctoral Clinical Fellow in the Genome Function Laboratory @TheCrick
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Reposted by Christina Kajba
crick.ac.uk
The Francis Crick Institute @crick.ac.uk · Sep 4
Congratulations to @gregfindlay.bsky.social on being awarded a €1.5 million Starting Grant from the @erc.europa.eu to take a closer look at possible disease variants hiding in the dark genome.

www.crick.ac.uk/news/2025-09...
€1.5 million to uncover disease risk hiding in non-coding DNA
Greg Findlay, Group Leader of the Genome Function Laboratory at the Francis Crick Institute, has been awarded a Starting Grant from the European Research Council for €1.5 million to take a deep dive i...
www.crick.ac.uk
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ckajba.bsky.social
Christina Kajba @ckajba.bsky.social · Sep 1
Looking forward to the Variant Effects Seminar tomorrow! @michaelherger.bsky.social and I will present our pooled prime editing platform for high-throughput variant screening.
varianteffect.bsky.social
Atlas of Variant Effects Alliance @varianteffect.bsky.social · Aug 7
Coming up in September!
➡️Christina Kajba @ckajba.bsky.social & Michael Herger @michaelherger.bsky.social — pooled prime editing screens in haploid human cells
➡️Jon Acosta — multiplexed in vivo base editing screens
#GeneticVariants #PrimeEditing
ℹ️https://www.varianteffect.org/seminar-series/
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Reposted by Christina Kajba
gregfindlay.bsky.social
Greg Findlay @gregfindlay.bsky.social · Aug 18
Our latest research is out today on ‪@medrxivpreprint.bsky.social:

www.medrxiv.org/content/10.1...

Saturation genome editing of BRCA1 across cell types accurately resolves cancer risk.

Led by the amazing Phoebe Dace. This one’s packed full of data, so check out the paper. Quick highlights… 🧵 1/n
Saturation genome editing of BRCA1 across cell types accurately resolves cancer risk
Germline pathogenic BRCA1 variants predispose women to breast and ovarian cancer. Despite accumulation of functional evidence for variants in BRCA1 , over half of reported single-nucleotide variants (...
www.medrxiv.org
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Reposted by Christina Kajba
gregfindlay.bsky.social
Greg Findlay @gregfindlay.bsky.social · Jun 16
Check out @ckajba.bsky.social and Michael Herger's concise description of their recent work. Thanks to Nature Reviews Genetics for featuring this.

rdcu.be/eraxZ
Determining variant effects with pooled prime editing
Nature Reviews Genetics - In this Tools of the Trade article, Christina Kajba and Michael Herger describe their screening platform, based on pooled prime editing, for large-scale functional...
rdcu.be
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