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Cytosurge AG @cytosurge.bsky.social · 1d

🏆 Dr. Gabriel Giger @ethz.ch (2025 Origins Federation @harvard.edu PhD Prize) used #FluidFM for groundbreaking artificial #endosymbiosis research!
🎬 👇
His @nature.com paper: 56K+ accesses, 99th percentile impact️ https://go.nature.com/4jPwdYa
More customer #stories ▶️ https://bit.ly/4pMCxT3

Cytosurge AG @cytosurge.bsky.social · 1d

#Anniversary #CRISPR @nobelprize.bsky.social

www.linkedin.com/posts/celled...

#anniversary #crispr #crispr #celledit #fluidfm #crispr #celledit | CellEDIT Service

#Anniversary Today, we celebrate The Nobel Prize awarded in 2020 to Emmanuelle Charpentier and Jennifer Doudna for developing #CRISPR‑Cas9 as a programmable gene-editing tool. Their breakthrough turne...

www.linkedin.com

Cytosurge AG @cytosurge.bsky.social · 6d

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Thanks to the #BiotechnetSwitzerland team, #CSEM, University of Applied Sciences and Arts Northwestern Switzerland @fhnw.ch for organizing this nice event.

#DataScience #LifeSciences #SingleCell #SameCell #LiveSeq

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Cytosurge AG @cytosurge.bsky.social · 6d

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• Longitudinality: True cell-level data pairs, not correlations
• Causality: #Samecell trajectories reveal perturbation → effect
• Multimodality: Connects phenotype, context & function with transcriptome 👇

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Cytosurge AG @cytosurge.bsky.social · 6d

2/ Live-cell sequencing #Liveseq stands out in this regard and may exhibit just the opposite: small datasets, yet highly informative. 👇

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Cytosurge AG @cytosurge.bsky.social · 6d

Great insights from "Life Science Industry Meets Data Science 2025" #BiotechnetSwitzerland.
@dossola.bsky.social
One concept came up a few times: "Lots of Data ≠ Lots of Information". This rings especially true in #NGS and #scRNAseq, where massive datasets often yield vague correlations. 👇

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Cytosurge AG @cytosurge.bsky.social · 6d

Static snapshots → pseudotime inference misses fast/rare/non-monotonic transitions. #LiveSeq tracks the same living cell over time, real trajectories, not assumptions. Within-cell causality for drug resistance, differentiation, and stress responses. Reach out + #webinar 👇 QR codes below. #SingleCell

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Cytosurge AG @cytosurge.bsky.social · 7d

See you there!

Cytosurge AG @cytosurge.bsky.social · 9d

Join our #webinar to learn more > events.teams.microsoft.com/event/06737e...

Cytosurge AG @cytosurge.bsky.social · 9d

Ever wonder what the butterfly effect looks like in molecular biology? 🦋
With #LiveSeq you can follow the same living cell over time — from tiny molecular flutter to dramatic transformation.
From correlation ➝ causation.

#SingleCell #CellBiology #ButterflyEffect #MolecularBiology #Transcriptomics

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Cytosurge AG @cytosurge.bsky.social · 13d

EMT is heterogeneous; endpoint scRNA seq = correlation. Live seq + #FluidFM follows the same living cell over time—imaging + longitudinal RNA → causation. @institutcurie.bsky.social applies it to EMT in #TNBC (chemo, MET, future multi omics). Read: www.cytosurge.com/blog/company...
#SingleCell

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Cytosurge AG @cytosurge.bsky.social · 15d

6/ LINKS in the announcement 👉 cytosurge.com/blog/press-r...

Cytosurge and Lexogen Announce Live-seq Workflow Readiness

Live-seq brings longitudinal, non-destructive cell sequencing to every lab, revealing new insights into cellular behavior

cytosurge.com

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Cytosurge AG @cytosurge.bsky.social · 15d

5/ Researchers are invited to an upcoming #webinar and encouraged to apply for Cytosurge’s Live-seq Access Program, which offers proof-of-principle studies for selected projects.💻 LINKS👇

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Cytosurge AG @cytosurge.bsky.social · 15d

4/ By preserving cell viability, researchers can repeatedly sample RNA from the same living cells, unlocking true longitudinal, time-resolved transcriptomics and causally linked molecular and phenotypic data for applications in #developmentalbiology, #cancerresearch, and #drugdiscovery.

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Cytosurge AG @cytosurge.bsky.social · 15d

3/ Developed through a year of joint effort, the workflow integrates Cytosurge’s #FluidFM® OMNIUM platform for minimally invasive cytoplasmic sampling, with #Lexogen’s LUTHOR HD kit for ultra-sensitive #RNAlibraryprep, plus comprehensive sequencing and data analysis support.

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Cytosurge AG @cytosurge.bsky.social · 15d

2/ This breakthrough enables labs of any size to repeatedly sequence the same living cells, directly observing how #geneexpression shapes cellular behavior over time. #singlecell

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Cytosurge AG @cytosurge.bsky.social · 15d

Cytosurge and #Lexogen announce that their integrated Live-seq workflow is now available to academic researchers and industry partners worldwide.

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Cytosurge AG @cytosurge.bsky.social · 17d

From collab to publication: #CellEDIT helped Dr. Siniuk @leibnizfli.bsky.social validate a p53 site KO in U2OS via vector-free intranuclear #CRISPR. @natgenet.nature.com (Jan 2025) reframes transcriptional interference, showing #CoCoProms as dynamic gene regulators. #FluidFM #SingleCell

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Cytosurge AG @cytosurge.bsky.social · 21d

Dr. Voorberg van der Wel @bprc-eu.bsky.social uses #FluidFM OMNIUM to target #hypnozoites, the dormant liver stage behind relapsing #malaria. #Singlecell nanoinjection/extraction + #Liveseq longitudinal RNA, with reduced animal use.
Customer stories playlist ▶️ https://bit.ly/4gwzbQ4

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Cytosurge AG @cytosurge.bsky.social · 23d

Stay ahead in single-cell research 🧬✨
• Real-time updates → Follow us
• Insights & events → Website
• Exclusive content → Newsletter: https://www.linkedin.com/newsletters/fluidfm-update-newsletter-7120776447593431041/

#LiveSeq #FluidFM #SingleCell #Transcriptomics #Webinars #Events

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Cytosurge AG @cytosurge.bsky.social · 27d

#ThrowbackThursday #TBT Our team swapped lab benches and desks for puzzles, trains, and lake views. The best part? Time together! 📸🌅

#TeamBuilding #TeamWork #LifeAtCytosurge #CompanyCulture #SummerEvent

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Cytosurge AG @cytosurge.bsky.social · Sep 8

Have a stubborn cell line? Let us know which ones you struggle with!

#FluidFM #CRISPR #GeneEditing #SingleCellEngineering #HardToTransfect #PrimaryCells #IntraNuclearInjection #RNP #CellEDIT @tobias-a-beyer.bsky.social

Cytosurge AG @cytosurge.bsky.social · Sep 8

What it unlocks 👇

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Cytosurge AG @cytosurge.bsky.social · Sep 8

When viral delivery, lipofection, or electroporation fall short, CellEDIT’s FluidFM-based intra nuclear injection offers a different path: force-controlled nanopipettes place CRISPR RNPs directly into the nucleus of a single cell, gently, precisely.

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Cytosurge AG @cytosurge.bsky.social · Sep 8

#CellEDIT101 Chapter 4: Overcome the “hard” in hard-to-transfect cells

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