3. If you haven't got a #flu shot yet, now's the time. You may have heard that there's likely a mismatch this year — the #H3N2 virus mutated after the vaccine strains were picked. More on that in a bit. But that's not a reason to skip getting a shot this year. www.statnews.com/2025/11/20/f...

Waiting for the day someone presents this type of stat juxtaposed against how often healthcare providers give misdirected or mistargeted information.

🤣

If we want preprints to really catalyze faster, more open science, then leading infrastructure needs to reduce this friction. Authors should know when feedback exists — otherwise we’re shouting into the void.

As an interesting data point, 4 of 5 women I told about this on the same day also experience significant pain from IUD insertion / replacement procedures and have (also) never been offered pain management options. (The fifth didn’t comment.)

We need to change this. Pass it on 👆🏼 to your friends.

As an interesting data point, 4 of 5 women I told about this on the same day also experience significant pain from IUD insertion / replacement procedures and have (also) never been offered pain management options. (The fifth didn’t comment.)

We need to change this. Pass it on 👆🏼 to your friends.

You can read the full research paper here:

doi.org/10.3390/epid...

Or, read my summary and highlights from the paper here: bit.ly/3J8yBLL

Let me know what questions you have!

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You can read the full research paper here:

doi.org/10.3390/epid...

Or, read my summary and highlights from the paper here: bit.ly/3J8yBLL

Let me know what questions you have!

(6/6)

The EPI/PEI-SS is available for anyone to use in the real-world right now: danamlewis.github.io/EPI-PEI-SS/

(You can also find it in PERT Pilot, for people who already have EPI and want to monitor symptom changes over time: bit.ly/PERT-Pilot-iOS, bit.ly/PERT-Pilot-Android)

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Note: diverse online population. Follow-up studies (e.g., general pop, common co-diseases like diabetes, pancreatic cancer, etc.) are in the works, to pair with elastase testing.

This study was not powered, but the data is being used to power the subsequent studies.

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EPI/PEI-SS higher in those with EPI (98.11, min 1, max 213) and lower in those without EPI (38.86, min 0, max 163).

Statistically significant difference (p<.001), remained even when those without EPI were split into two groups based on other GI-related conditions or not.

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The EPI/PEI-SS has 15 symptoms (abdominal, toilet-related, food-related symptoms) and rates by frequency (0-5) and severity (0-3).

The score is based on frequency x severity, for a max total score of 225.

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Agree it was weird. I wonder if their push to get free users onto it is what the reason was. (As a plus user, I dislike the lack of choice and lack of communication about it.)

One way to stress test includes thinking about 1) newer folks w/less volume+experience & 2) citizen/community (or non-academic/industry) researchers

Either 1 or 2 have less volume and existing reputation/cred to spend in such a system, same for if publishing in a new/adjacent field of study.

I understand to a degree (as someone with celiac, at least, plus EPI - have also done low FODMAP in past). It’s hard when there are so many GI-related things going on!

Have you had any success identifying which symptoms seem to correlate with which condition?