Adults (average BMI 25) ate:

2 cups fruit daily or none for 8 wk

(8-wk "washout period" - pretty good, all considered)

Fruit (including bananas, apples, oranges, watermelon)

👉 ⬆️ some blood nutrients
👉BUT insulin resistance better without the fruit

cdn.nutrition.org/article/S247...

The notion of "ultra-processed" food is so complicated, not even @fda.gov knows how to define it.

There's a simpler way. Focus on the main health offenders:

👉Refined grains, sugar, and other highly processed carbs.

In print today.
Free online access (requires email) wapo.st/3WuPHGJ

Certified for 1-oar rowing today in Hellerup, Denmark (where we live part time).

I don't believe I have Viking ancestors, but if I do, they would be proud. 😀

Debating the Carbohydrate-Insulin Model with John Speakman in Cell Metabolism.

Letter-to-the-Editor (open access) authors.elsevier.com/a/1lCYr5WXUl...

Reply www.cell.com/cell-metabol...

Anti-depressant therapy for Danish winter.

👉Hellerup harbor, water temp 2° C

NOON, Denmark. Circa solstice. View to the South.

In case you were wondering, that moderately bright object about 10° above the horizon is ... the sun 😲

Last day of 5-day fast. Nice ketone bump.

Overall, went well. Day 3 was the hardest. Now feeling good, little hunger, consistent energy.

Admittedly, looking forward to first meal this afternoon. Will build up slowly, 3 days.

PLANS: 1 day fast every couple weeks. Longer fast every 3 months.

Fast Day 4.

Feeling better today, after some hunger and mental fuzziness yesterday.

Entering deeper ketosis, BOHB 3.4 ... a bit ahead of schedule.

Will probably end fast tomorrow evening, after completing day 5 (rather than 6 as originally planned).

Do medical tailored meals improve T2 diabetes?

Treatment group received home delivery of 12 meals weekly for 3 months + supports

Meals per Am Heart Association guidelines, each with 60g carb (add snack, total daily carb = 200g)

👉"Intervention uptake was good but did not improve clinical outcomes"

N=1 experiment:

Prolonged total fast, just coffee & electrolytes.

Completing Day 2 of planned 6 days.

Surprisingly easy so far, no hunger, good energy (15k ride no problem).

Will see about longterm benefits. (Immediate benefit, no need to floss).

(Do seek expert guidance if trying first time)

Trondheim 9:30 am

About half hour till sunrise 😬

Lecturing in Norway.

Today, lovely Trondheim. View from “Old Town” at sunset

… about 2:30 pm 😱

In this week's JAMA REVISITED. Originally published in December 1924

And happy Thanksgiving to my North American friends

On Diabetes in JAMA

👉GUESS the original publication date (see thread 2/2)

"a consistent and great actual increase in the diabetes death rate has occurred"

"the cause of ... this metabolic disorder is not apparent"

"Perhaps ... the higher carbohydrate [has contributed]"

1/2

Delighted to give the opening keynote at the Novo Nordisk Foundation Metabolism in Action meeting

Paradigm Clash in #Obesity Cause and Effect
#carbohydrateinsulinmodel
@metabolcenter.bsky.social

For the full theory, see: www.nature.com/articles/s41...