Catherine Denicourt
@denicourt-lab.bsky.social
RNA Lab studying ribosomes biogenesis and how rRNA and tRNA modifications regulates translational reprogramming in cancer at UTHealth
Reposted by Catherine Denicourt
These exciting new results therefore have important implications for recoding of the genetic code for synthetic biology purposes and in the use of suppressor tRNAs for premature stop codon readthrough in human diseases. Congrats everyone!
rdcu.be/eAcLz
rdcu.be/eAcLz
An RNA modification prevents extended codon-anticodon interactions from facilitating +1 frameshifting
Nature Communications - tRNAs contain many chemical modifications that regulate their function. Integrating smFRET and cryo-EM approaches, this work demonstrates that m1G37 in tRNAProL stabilizes...
rdcu.be
August 12, 2025 at 11:13 AM
These exciting new results therefore have important implications for recoding of the genetic code for synthetic biology purposes and in the use of suppressor tRNAs for premature stop codon readthrough in human diseases. Congrats everyone!
rdcu.be/eAcLz
rdcu.be/eAcLz
Ok, wow. Mine was reviewed Oct 2024 (7%ile) and no news. NIGMS should really update their funding policy page. Had I known…
July 31, 2025 at 5:49 PM
Ok, wow. Mine was reviewed Oct 2024 (7%ile) and no news. NIGMS should really update their funding policy page. Had I known…
Which Council was this for? Did your PO confirm it would not be funded? All my PO can say is "I have no information "
July 31, 2025 at 4:59 PM
Which Council was this for? Did your PO confirm it would not be funded? All my PO can say is "I have no information "
Yes, grant reviewed early February and received summary statement on March 5
April 3, 2025 at 7:55 PM
Yes, grant reviewed early February and received summary statement on March 5
Reposted by Catherine Denicourt
NIH grants that created genetic medicine cured my hemophilia in 2020. Here is what the 5-years cured blood test looked like last week. Science works! I hope others get the benefits of such research before regressive Republicans send us back to the 19th Century.
February 9, 2025 at 5:17 PM
NIH grants that created genetic medicine cured my hemophilia in 2020. Here is what the 5-years cured blood test looked like last week. Science works! I hope others get the benefits of such research before regressive Republicans send us back to the 19th Century.
Also wondering about that and Advisory Council meetings. NIGMS Council is scheduled this week
February 3, 2025 at 3:27 PM
Also wondering about that and Advisory Council meetings. NIGMS Council is scheduled this week