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epicentre-msf.bsky.social
@epicentre-msf.bsky.social
Epidemiology, medical research, innovation and training group embedded in Medecins Sans Frontieres. Design & carry out projects in complex and unstable settings
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Hello to everyone on Bluesky 👋

We are a Médecin sans Frontières (MSF) satellite dedicated to epidemiology, medical research, innovation and training.

Find out more about us ⤵️
epicentre.msf.org/en/epicentre...
Who we are?
Epicentre, an MSF Satellite dedicated to epidemiology and research
epicentre.msf.org
How can HIV prevention be made more accessible to the populations most at risk?
In Malawi, Epicentre and MSF are conducting a study to document the introduction of CAB-LA among sex workers, a group particularly at risk of HIV infection.
#VIH #PrEP
epicentre.msf.org/en/news/anal...
Analyzing the acceptance, adoption and impact of new HIV prevention tools: a study among sex workers in Malawi
Since 2022, the World Health Organization (WHO) has recommended long-acting injectable cabotegravir (CAB-LA) as an innovative method of pre-exposure prophylaxis (PrEP) against HIV. Epicentre in partne...
epicentre.msf.org
December 1, 2025 at 2:29 PM
On recrute un.e responsable des activités épidémiologiques pour la mission Tchad de MSF France. Vous avez un diplôme en épidémiologie ou en santé publique, postulez ci-dessous 👇🏾
smrtr.io/vWCQ3
Responsable des Activités Epidémiologiques (H/F), CDD 12 mois, basé (e) à N'Djaména - Tchad
Description de l'entreprise: Créée par Médecins Sans Frontières (MSF) en 1986, Epicentre mène des activités d’épidémiologie de terrain, de formation et de recherche médicale en appui aux objectifs hum...
smrtr.io
December 1, 2025 at 9:31 AM
Lung ultrasound (LUS) shows promise in TB diagnosis
➡️High sensitivity, comparable to chest X-ray, but lower specificity
✅Valuable where radiography is unavailable
✅a new scoring system developed improves accuracy, but further validation is needed
www.sciencedirect.com/science/arti...
Diagnostic Accuracy of Lung Ultrasound for Pulmonary Tuberculosis in out-patients from Papua New Guinea, a Resource-Limited setting
to evaluate the diagnostic accuracy of lung ultrasound (LUS) for pulmonary tuberculosis (PTB) in Papua New Guinea.Prospective observational study incl…
www.sciencedirect.com
November 27, 2025 at 3:12 PM
🌍#WorldAMRWeek
Replay our Scientific Day session on Diagnostics for Antibiotic Stewardship:
✔ Avoid inappropriate STI treatments
✔ Why cumulative antibiograms matter
✔ Rapid tests for carbapenemase-producing bacteria in MSF labs
🎥 Watch now: youtu.be/FlwmAVONDuo
Session | Diagnostics for Antibiotic Stewardship
YouTube video by Epicentre - MSF
youtu.be
November 21, 2025 at 3:12 PM
How can we better protect children from malaria in highly seasonal regions?
Epicentre is pleased to be part of the Imvacs Project testing an integrated approach: combining the R21/Matrix-M vaccine with Seasonal Malaria Chemoprevention for children in Mali & Burkina Faso.
youtu.be/r2v9EvWQ1JE?...
World Children’s Day 2025
YouTube video by IMVACS Project
youtu.be
November 20, 2025 at 1:38 PM
Just announced at #WCLH2025: WHO treatment decision algorithms could nearly double pediatric TB diagnoses and treatments.
This breakthrough could save thousands of lives—urgent adoption is needed.

epicentre.msf.org/en/news/who-...
WHO treatment decision algorithms double pediatric TB diagnoses and treatments: Findings from MSF/Epicentre
At the World Conference on Lung Health held from November 18 to 21, 2025, in Copenhagen, Médecins Sans Frontières (MSF) and Epicentre have revealed that using the treatment decision algorithms recomme...
epicentre.msf.org
November 18, 2025 at 3:14 PM
Our study in BMJ Global Health assessed three prenatal nutrition strategies in rural Niger to improve maternal health and reduce adverse pregnancy outcomes.
Findings: no significant differences between approacheshttps://gh.bmj.com/content/10/11/e021013
Effect of prenatal multiple micronutrient supplements and medium-quantity lipid-based nutritional supplements on maternal weight gain and infant birth weight in rural Niger: a cluster-randomised trial
Introduction The risk of adverse birth outcomes, such as low birth weight (<2500 g, LBW), is associated with poor maternal nutrition and weight gain in pregnancy and can increase the risk of infant mo...
gh.bmj.com
November 14, 2025 at 1:26 PM
On November 13 at 3 p.m. CET, join writer and advocate for the fight against tuberculosis @johngreensbluesky.bsky.social for a live YouTube roundtable co-hosted by MSF on improving care for children with TB—nearly half of 1.2M cases in 2024 went undiagnosed.
#EndTB
www.youtube.com/watch?v=XBqQ...
Fighting TB in Kids: A Discussion with Doctors without Borders
YouTube video by vlogbrothers
www.youtube.com
November 13, 2025 at 8:55 AM
Maths in action for malaria prevention @astmh.bsky.social ! 🦟
A mathematical model, using routine surveillance & climate data, helped define the optimal strategy for seasonal malaria chemoprevention in southern Chad @swisstph.ch
#TropMed25
November 12, 2025 at 10:21 AM
New randomized, controlled trial results @astmh.bsky.social show longer intervals (6 & 12-month) between Euvichol-Plus® may be considered an alternative to the recommended 14-day regimen in adults and children. A promising option amid vaccine shortages and delayed 2nd doses.
#TropMed25 #6469
November 10, 2025 at 3:46 PM
Come see us at @astmh.bsky.social from November 9 to 13.
Find us at BOOTH #215, where we’ll be joining forces with MSF and @dndi.org
And don’t miss posters and oral presentation which will feature some of our work. #6469 #6169 #6981 #7782
#TropMed25 #ASTMH2025
November 6, 2025 at 2:38 PM
Doubling rifampicin dosing helps more patients reach therapeutic levels in HIV–TB coinfection.
EFV-based ART slightly - but not significantly - affects rifampicin & isoniazid PK.
➡️ Safety & efficacy of the combined regimen
academic.oup.com/jac/advance-...
Pharmacokinetics of rifampicin and isoniazid in patients with HIV–tuberculosis coinfection receiving efavirenz-based antiretroviral treatment: an ANRS12292–RIFAVIRENZ sub-study
AbstractBackground. Increasing rifampicin dosing is considered a potent strategy for shortening TB treatment duration. Although previous data among patient
academic.oup.com
October 30, 2025 at 2:54 PM
In Mali, an ancillary study compares two R21/Matrix-M vaccine formulation —10-dose vs. 2-dose—to simplify logistics, as part of the broader #IMVACS project which aims to evaluate the effectiveness of a new integrated strategy for administering this vaccine.
www.imvacs.org/safli-r21-10/
SAFLI-R21-10 - IMVACS
SAFLI-R21-10 SAFLI-R21-10 is an ancillary study conducted within the framework of the broader IMVACS project but under a stand-alone protocol separate from the main IMVACS study. This study is designe...
www.imvacs.org
October 28, 2025 at 11:37 AM
📹 Modeling to guide humanitarian action
Hugo Soubrier explains how modeling can help MSF make faster and more informed decisions during epidemics such as Ebola in the DRC and hepatitis E in South Sudan.
#HumanitarianAid #Epidemiology #Modeling #MSF
youtu.be/Wfqo8oOYi6U?...
Modéliser pour mieux agir : comment la modélisation peut guider l’action humanitaire
YouTube video by Epicentre - MSF
youtu.be
October 23, 2025 at 2:57 PM
A promising cervical screening strategy for low-resource settings combining:
✅ HPV testing
✅ automated cervical visual evaluation
… to accurately identify women most at risk of precancer (CIN3+).
Data from 9 countries confirm strong predictive power.
academic.oup.com/jnci/article...
Initial evaluation of a new cervical screening strategy combining human papillomavirus genotyping and automated visual evaluation: the Human Papillomavirus–Automated Visual Evaluation Consortium
Abstract. The HPV-Automated Visual Evaluation Consortium is validating a cervical screening strategy enabling accurate cervical screening in resource-limit
academic.oup.com
October 20, 2025 at 12:53 PM
In KwaZulu Natal, South Africa, over 10% remain at risk of transmitting HIV — often unaware of their status or without viral suppression.
Prevention, tailored care & access to injectable PrEP are key.
⚠️ But PEPFAR funding cuts threaten progress.
epicentre.msf.org/en/news/hiv-...
HIV in South Africa: Identifying and targeting the last strongholds of the epidemic with a view to reversing it
To gain a better understanding of the issues at stake in terms of HIV prevention and action, Jihane Ben-Farhat has carried out an in-depth analysis of risk behaviors in KwaZulu Natal, South Africa. He...
epicentre.msf.org
October 14, 2025 at 2:34 PM
One step further in decentralizing care for SAM
First large RCT shows caregiver training boosts knowledge & confidence in at-home monitoring of children with uncomplicated SAM in community-based treatment.
gh.bmj.com/content/10/1...
Effect of caregiver training on knowledge and confidence of at-home clinical and anthropometric surveillance of children with uncomplicated severe acute malnutrition: analysis of a cross-over cluster ...
Introduction Patient-centred task-shifting models may be a promising strategy in the community-based management of severe acute malnutrition (SAM) to alleviate pressure on health systems and increase ...
gh.bmj.com
October 13, 2025 at 7:51 AM
Sharing findings from the GastroSAM study, which compared intravenous and oral rehydration in children with severe acute malnutrition. The Niger site was supervised by our center, in collaboration with MSF Switzerland, contributing directly to this important research.👇
The GASTROSAM trial involving children with severe acute malnutrition and gastroenteritis showed no evidence of a difference in mortality at 96 hours between oral and intravenous rehydration strategies. Full trial results and Research Summary: nej.md/3TjfSP7

#MedSky #PedSky #GastroSky
October 7, 2025 at 7:30 AM
Au Mali, 77% des femmes atteintes d’un cancer du sein sont diagnostiquées à un stade avancé.
Et pourtant, une étude menée par Epicentre montre que l’approche multidisciplinaire de MSF a permis d’atteindre 72% de survie à 3 ans contre 12,7% en 2015.
#OctobreRose
youtu.be/81o5tL4BcuY?...
Lutter contre le cancer du sein au Mali, un défi possible
YouTube video by Epicentre - MSF
youtu.be
October 1, 2025 at 12:15 PM
A new meta-analysis shows that, ten years after its introduction in the Sahel, seasonal malaria chemoprevention (SMC) reduces the incidence of malaria in children under 5.🔽
September 22, 2025 at 1:17 PM
Hypertension affects 1 in 5 people in parts of Kenya.
Despite efforts to decentralize care and introduce single-pill treatments, access remains limited—especially in remote rural areas.
Social sciences help tailor care to local realities.👇
epicentre.msf.org/en/news/beyo...
Beyond the numbers: why the social sciences are essential for evaluating differentiated models of hypertension care and facilitating the decentralization of care
In some regions of Kenya, more than one person in five is now affected by hypertension (1). However, treatment is still too limited, despite the introduction of single-pill combination therapies and e...
epicentre.msf.org
September 17, 2025 at 12:21 PM
Reposted
Les médecins ne peuvent pas arrêter un génocide. Nos dirigeants, OUI !

#MSF demande à la #France d’utiliser tous les leviers politiques, diplomatiques et économiques dont elle dispose afin d’obtenir d’ #Israël :
September 15, 2025 at 2:31 PM
Using surveillance data from MSF’s Bentiu vaccine study, we evaluated the performance of the tests.
The Assure RDT showed good sensitivity (86%), outperforming PCR and specificity comparable to ELISA (94.7%).
✅ Supports its use in Hep E surveillance
academic.oup.com/jid/advance-...
Validate User
academic.oup.com
September 10, 2025 at 3:29 PM
🎗️Childhood Cancer Month
In Uganda, ~3,000 children develop cancer each year — but only 1,000 are diagnosed, often at advanced stages. Poor access to care, low awareness & social barriers make early diagnosis a challenge.
In Mbarara, we’re leading 2 studies to change that⬇️
September 4, 2025 at 11:40 AM
Lessons from the measles outbreak in Kismayo, Somalia (2020–2021):
🔹 Attack Rates: 12% in children <5, 17% among IDP children
🔹 Case Fatality Ratios: 5.9% in children <5, 11.5% among IDP children
➡️ Urgent need to:⬇️
September 2, 2025 at 12:23 PM