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fthoma.bsky.social
@fthoma.bsky.social
· Aug 12
Local Mitochondrial Physiology Defined by mtDNA Quality Guides Purifying Selection
The mitochondrial genome (mtDNA) encodes essential subunits of the electron transport chain and ATP synthase. Mutations in these genes impair oxidative phosphorylation, compromise mitochondrial ATP pr...
www.biorxiv.org