Lightnews — Scholar-powered news

Reposted by Glasgow Gut Science

Gwo-tzer Ho @gwotzerho.bsky.social · 9d

www.gla.ac.uk/postgraduate...

We have a fantastic #PhD opportunity looking at iron-mitochondria-inflammation with @jimbrewer84 and Caroline Dewar @LancasterUni! Looking for great candidates. 🙏 apply below:

University of Glasgow - Postgraduate study - Centres for Doctoral Training - NorthWest Biosciences - Our Projects - Underpinning Bioscience - Gwo-tzer Ho

www.gla.ac.uk

1 2

Reposted by Glasgow Gut Science

University of Glasgow School of Infection & Immunity @uofgsii.bsky.social · Aug 15

🆕 | @uofgsii.bsky.social's Professor @gwotzerho.bsky.social has received £310k from Jon Moulton Charity Trust to support his UK investigator-led Phase 2 Marvel Study, investigating use of oral mitochondrial antioxidants in the treatment of ulcerative colitis.

👉 More: www.gla.ac.uk/schools/infe...

A head and shoulders portrait shot of Professor Gwo-tzer Ho stood outside in front of a marble pillar.

1 1 2

Reposted by Glasgow Gut Science

Gwo-tzer Ho @gwotzerho.bsky.social · Jul 11

Two wonderful talents. Congratulations Duncan Rutherford and Robert Whelan. PhD graduation ceremony at Edinburgh University. Graduates from the Ho-lab. Proud supervisor 🥲.
#PhD #Scicomm

1 3

Glasgow Gut Science @glasgowgutscience.bsky.social · May 3

Very proud of our CCUK Research Champion Emma Pryde in this month's Crohns Colitis Connect edition. You've been amazing!

#IBD #PPIE Read her story...

crohnsandcolitis.org.uk/get-involved/b…

A picture paints a thousand words!

Glasgow Gut Science @glasgowgutscience.bsky.social · May 3

Our group have studied whether stool #calprotectin vs. #QFIT (that can detect blood used as screening for bowel cancer) to monitor #IBD . 💩

We are looking for the 'patient voice' in our study, so very grateful for your time, share and RT!
crohnsandcolitis.org.uk/get-involved...

Can we improve how to monitor Inflammatory Bowel Disease?

Researchers at University of Glasgow are looking for people living with IBD and who have undergone poo testing as part of their clinical care to complete a short online survey to help them develop way...

crohnsandcolitis.org.uk

2 2

Glasgow Gut Science @glasgowgutscience.bsky.social · Mar 24

A radiant and authentic perspective.

Our patients have presented this but the full version is worth reading!

Very proud of our patient-public involvement group in Glasgow, Edinburgh and England. Thanks to all our patients who have contributed and Crohn's Colitis UK.

Glasgow Gut Science @glasgowgutscience.bsky.social · Mar 24

Our PPI IBD patients Molly and Tricia came out with the 'Patient-led' effort.

We handed over the reins 100%.

Our patient group met, discussed and wrote up this paper over 6 months.

1

Glasgow Gut Science @glasgowgutscience.bsky.social · Mar 24

In 2023, 1315 IBD patients from UK & globally took part in our work and left 415 specific comments about IBD and their lives.

Precious data.

But how to capture, analyse and present this? We asked our patients.

1

Glasgow Gut Science @glasgowgutscience.bsky.social · Mar 24

What happens if we let our patients take the lead in an IBD project?

Result: A 100% patient-led paper on, 'What it means to live with IBD'

Produced 100% by patients.

With no input from analytical tools, clinicians, KOLs and pharma input.

🧵
www.medrxiv.org/content/10.1...

#Crohn's #Colitis #IBD

Patient-public involvement (PPI)-led qualitative analysis of >400 Inflammatory Bowel Disease patient responses in United Kingdom: An independent patient-led review to provide insights to improve ca...

Background: This paper investigates a patient-led approach to research on wellbeing in individuals with Inflammatory Bowel Disease (IBD). Traditionally, Public and Patient Involvement (PPI) groups hav...

www.medrxiv.org

1 2

Glasgow Gut Science @glasgowgutscience.bsky.social · Mar 13

Great to host Chris Lucas from Edinburgh to give the @uofgsii.bsky.social Immunology seminar, on #macrophage #epithelial combined roles in #lung regeneration, key steps to new translational science in respiratory medicine. And learning across disciplines!

4 13

Glasgow Gut Science @glasgowgutscience.bsky.social · Feb 26

Stem cells and #immunometabolism in Ulcerative Colitis
@uofgsii.bsky.social #ibd #scicomm

Gwo-tzer Ho @gwotzerho.bsky.social · Feb 20

Great effort by Duncan at ECCO meeting, Berlin. In UC gut stem cells, not only is there mitochondrial dysfunction (power failure) but loss of ketogenesis (backup power) is the critical tipping point. #mitochondria #ketogenic #ECCO2025 #colitis #stemcells #ibd Proud supervisor

1 3

Glasgow Gut Science @glasgowgutscience.bsky.social · Feb 24

Unique hyperinflammatory macrophages on the same time slams on the 'brakes' #ACOD1 in #Crohns beautifully presented by Gareth Jones #ECCO2025 in Berlin. #macrophages

Biology is just so interesting @uofgsii.bsky.social @gastrogrj.bsky.social @bainlab.bsky.social

4 12

Glasgow Gut Science @glasgowgutscience.bsky.social · Feb 23

East-West connection made with China Crohn's & Colitis Foundation in #ECCO2025 Berlin! ✨️ #IBD #China #Crohn's

1

Glasgow Gut Science @glasgowgutscience.bsky.social · Feb 14

A good week for study, we recruited 4 (!) patients into MARVEL inc 1st patient in #Manchester thanks to Pro Limdi's wonderful team. Mitochondrial antioxidants in UC www.marvelstudy.uk. Novel ways to treat IBD. #ibd #ulcerativecolitis #mitochondria

2

Glasgow Gut Science @glasgowgutscience.bsky.social · Feb 7

We're making good progress in our MARVEL IBD trial www.marvelstudy.uk oral mitochondrial antioxidants in Ulcerative Colitis. Thus week our fab team in #Glasgow recruited a further 2 patients, nearly n=60 (target 200). 😀 #ibd #Colitis #mitochondria #trials

1 5

Glasgow Gut Science @glasgowgutscience.bsky.social · Feb 3

On the insightful paper by Benita Salomon utilising large scale proteomics in IBD. academic.oup.com/ecco-jcc/adv...

Characterization of Inflammatory Bowel Disease Heterogeneity Using Serum Proteomics: A Multicenter Study

AbstractBackground. Recent genetic and transcriptomic data highlight the need for improved molecular characterization of inflammatory bowel disease (IBD).

academic.oup.com

2

Glasgow Gut Science @glasgowgutscience.bsky.social · Feb 3

academic.oup.com/ecco-jcc/art...
A fantastic 1st author editorial contribution by our IBD fellow Peter and colleague @rahulkalla.bsky.social on what's our understanding of blood proteins in #IBD. #crohns #Colitis #biomarker @gwotzerho.bsky.social

Decoding the proteomic landscape of inflammatory bowel disease

Inflammatory bowel disease (IBD) is a complex and heterogeneous condition that poses significant challenges for diagnosis and treatment. Traditional classi

academic.oup.com

1 1 5

Glasgow Gut Science @glasgowgutscience.bsky.social · Feb 1

@uofgsii.bsky.social @gwotzerho.bsky.social

Glasgow Gut Science @glasgowgutscience.bsky.social · Feb 1

We have moved! Previously in Edinburgh, our group is mainly in School of Infection and Immunity, @uofglasgow.bsky.social. Very excited to work with new friends + partners and continue to share our work inc www.musicstudy.uk & www.marvelstudy.uk in IBD. #ibd #crohns #colitis #research #Glasgow

1 2

Glasgow Gut Science @glasgowgutscience.bsky.social · Feb 1

We have moved! Previously in Edinburgh, our group is mainly in School of Infection and Immunity, @uofglasgow.bsky.social. Very excited to work with new friends + partners and continue to share our work inc www.musicstudy.uk & www.marvelstudy.uk in IBD. #ibd #crohns #colitis #research #Glasgow

3 7