greatysp.bsky.social
Leo Yuan
@greatysp.bsky.social
38 followers 53 following 4 posts
Senior Scientist @Altos Labs | Formerly Stem Cell / Cancer Bio at @thefuchslab.bsky.social @rockefelleruniv.bsky.social @hhmi.bsky.social & Pulmonary Bio at @ucsfmedicine.bsky.social | Co-founder @Aer Therapeutics | Theatre & Art Lover | Adventurer
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Reposted by Leo Yuan
thefuchslab.bsky.social
Elaine Fuchs Lab @thefuchslab.bsky.social · Jun 12
New paper alert! We report in @cp-cellmetabolism.bsky.social how serine regulates stem cell fate in physiology and upon wounding.
Good work, Jesse and collabs!
www.cell.com/cell-metabol...
The integrated stress response fine-tunes stem cell fate decisions upon serine deprivation and tissue injury
Novak et al. discover that dietary serine impacts whether hair follicle stem cells (HFSCs) prioritize hair growth or skin repair after injury. HFSCs gauge metabolic stress using the ISR and accelerate...
www.cell.com
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greatysp.bsky.social
Leo Yuan @greatysp.bsky.social · May 29
Fantastic talk by @thefuchslab.bsky.social on the highly anticipated work on inflammatory memory with aging… congratulations to @chris-cowley14.bsky.social @rajsajjath.bsky.social et al
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greatysp.bsky.social
Leo Yuan @greatysp.bsky.social · Feb 11
Congratulations to @jorgealmagro.bsky.social and @thefuchslab.bsky.social as well!! 🎊🎉🥳🥳 @rockefelleruniv.bsky.social @hhmi.bsky.social
natrevcancer.nature.com
Nature Reviews Cancer @natrevcancer.nature.com · Feb 11
🥳 Our 4th most downloaded article in 2024:

Beyond genetics: driving cancer with the tumour microenvironment behind the wheel by @thefuchslab.bsky.social & colleagues

https://bit.ly/42Cvr...

@rockefelleruniv.bsky.social @hhmi.bsky.social @natureportfolio.bsky.social #NRCtop10of2024
Beyond genetics: driving cancer with the tumour microenvironment behind the wheel - Nature Reviews Cancer
In their Review article, Fuchs and colleagues discuss how a single or a few mutations in adult cells can lead to invasive cancers without a high mutational burden, demonstrating that non-genetic factors induce the epigenetic changes necessary for tumorigenesis.
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Reposted by Leo Yuan
thefuchslab.bsky.social
Elaine Fuchs Lab @thefuchslab.bsky.social · Jan 29
Our first 2025 paper!
We discuss in @natrevmcb.bsky.social how epithelial stem cells mechanically sculpt tissues, and how these forces are altered in cancer.
Great work from our former and current tumor mechanobiology experts Vince Fiore & @jorgealmagro.bsky.social 👏
www.nature.com/articles/s41...
Shaping epithelial tissues by stem cell mechanics in development and cancer - Nature Reviews Molecular Cell Biology
Adult stem cells self-renew and differentiate to build, maintain and repair tissues. This Review discusses recent insights into the contribution of mechanical forces produced by epithelial stem cell a...
www.nature.com
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Reposted by Leo Yuan
natrevmcb.nature.com
Nature Reviews Molecular Cell Biology @natrevmcb.nature.com · Jan 29
Shaping epithelial tissues by stem cell mechanics in development and cancer
Nature Reviews Molecular Cell Biology, Published online: 29 January 2025; doi:10.1038/s41580-024-00821-0Adult stem cells self-renew and differentiate to build, maintain and repair tissues. This Review discusses recent insights into the contribution of…
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greatysp.bsky.social
Leo Yuan @greatysp.bsky.social · Jan 29
Congratulations to @jorgealmagro.bsky.social @thefuchslab.bsky.social @rockefelleruniv.bsky.social @hhmi.bsky.social for this landmark review! And happy snake year! 🐍🧧
jorgealmagro.bsky.social
Jorge Almagro @jorgealmagro.bsky.social · Jan 29
Very happy to see our review out in @natrevmcb.bsky.social!
Here we discuss how stem cells exert forces to sculpt tissues in development and homeostasis, and how stem cell mechanics go awry upon malignant transformation. Read it here 👇
www.nature.com/articles/s41...
Shaping epithelial tissues by stem cell mechanics in development and cancer - Nature Reviews Molecular Cell Biology
Adult stem cells self-renew and differentiate to build, maintain and repair tissues. This Review discusses recent insights into the contribution of mechanical forces produced by epithelial stem cell a...
www.nature.com
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Reposted by Leo Yuan
jorgealmagro.bsky.social
Jorge Almagro @jorgealmagro.bsky.social · Jan 9
Kicking off 2025 Paper of the Week with @kevinng.bsky.social & @fesubtil.bsky.social. Today we discussed our friend @martinaparigi.bsky.social et al. recent paper in @nature.com. How do epithelia unlink necessary drivers of regeneration from malignant transformation?
www.nature.com/articles/s41...
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Reposted by Leo Yuan
kevinng.bsky.social
Kevin Ng @kevinng.bsky.social · Jan 10
Dog seeks coq au vin
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greatysp.bsky.social
Leo Yuan @greatysp.bsky.social · Jan 2
Proud to be part of the journey! @thefuchslab.bsky.social @jorgealmagro.bsky.social @rockefelleruniv.bsky.social
thefuchslab.bsky.social
Elaine Fuchs Lab @thefuchslab.bsky.social · Dec 31
2024 was a year of exciting discoveries and scientific discussions! A thread 🪡 of this years’ publications from our lab 👇🏼
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