GcL
@grosscol.bsky.social
92 followers 77 following 60 posts
Programming and human genetics. Working with TOPMED data and providing a view into human variation via BRAVO (bravo.sph.umich.edu)
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grosscol.bsky.social
That's a heck of a Lego endeavor! Impressive is an understatement.
grosscol.bsky.social
Reminds me of a project that had to satisfy a requirement of a contact specifying the solution needed to use machine learning.

We found a linear regression model that worked well enough, and made sure we never clarified beyond "supervised machine learning implementation" in the docs.
grosscol.bsky.social
@bcdreyer.social how do you edit copy? I thought paste took care of that?! /S
grosscol.bsky.social
Excellent. More great work of yours that I will unabashedly yoink for my own collaborative story telling with friends. Thank you.
grosscol.bsky.social
@@cherylrofer.bsky.social I came across a post of yours, checked your profile, and found that I liked both.

I have heard a lot about thorium reactors in recent years. What are your thoughts on thorium and thorium reactors?
grosscol.bsky.social
Watched this yesterday in the background. While nodding along, the offhand comment that you've written a compiler in assembly got my full attention. That's one of the projects where curiosity and masochism share a border.
grosscol.bsky.social
Most people don't have the ability to point out the hallmarks of fascism. My go-to recommendation is en.m.wikipedia.org/wiki/How_Fas...
How Fascism Works - Wikipedia
en.m.wikipedia.org
grosscol.bsky.social
Most people don't have the ability to point out the hallmarks of fascism. My go-to recommendation is en.m.wikipedia.org/wiki/How_Fas...
How Fascism Works - Wikipedia
en.m.wikipedia.org
grosscol.bsky.social
Trimming the hedges around the base of the tent helps as well.
grosscol.bsky.social
Unfortunately for us on this side of the border, that is a safer and saner stance for you.
grosscol.bsky.social
Tipsy women lazing about in pubs handing out cubes is no basis for a system of government!
grosscol.bsky.social
*it was originally written in the 1970s
*It has a learning curve
*It is a command line interface

It's blazingly fast to execute and works even when the input has millions of lines.
grosscol.bsky.social
Had no clue who you or Heather were, but "commie podcast hags" sold me on following both of you immediately.
grosscol.bsky.social
Using an ai generated image for the design feels bad.
grosscol.bsky.social
This post reads like it was written by an LLM
grosscol.bsky.social
Those that know history are done to watch everyone else repeat it.
grosscol.bsky.social
Being able to hear the disk drive grinding and grumbling away as it reads the floppy disk is an important part of the authentic Oregon Trail experience. Also, where in the world is Carmen Sandeigo?
grosscol.bsky.social
Interesting read. I do enjoy surprises in sufficiently powered well conducted research as they often elucidate the presence of previously unknown mechanisms.

Regarding science reporting , I wish the article had direct citations for the studies and links to relevant publications.
grosscol.bsky.social
My desire to remain informed is at odds with my desire to remain sane.
grosscol.bsky.social
Your cutting edge comics are always on point.
grosscol.bsky.social
There's always a Pratchett quote.
Reposted by GcL
kmichaelpollard.bsky.social
If you want something written about the human genome that is not complex science, then this is a good place to start. 🧪
Photo of the cover of the book "The Mysterious World of the Human Genome" by Frank Ryan.
grosscol.bsky.social
The keyword is breakdown. The meal worms breakdown a substantial amount of the ingested styrofoam.
Reposted by GcL
leahshaffer.bsky.social
#ScienceSky 🧪
jonathanwosen.bsky.social
If you run a life science lab where research has either significantly slowed or shut down completely due to Trump administration policies, I’d like to hear your story. I'm a biotech and life sciences reporter for @statnews.com, and you can reach me at [email protected] #journorequest