banner
helenelab.bsky.social
Helene Schmidt
@helenelab.bsky.social
100 followers 130 following 5 posts
Group Leader at Ernst Struengmann Institute for Neuroscience in Frankfurt. The more synapses the better #connectomics.
Posts Media Videos Starter Packs
helenelab.bsky.social
Helene Schmidt @helenelab.bsky.social · May 5
Hi, we didnt analyse astrocytes in that dataset. But maybe this helps you further, this study looked at astrocytes in EM data (cortex) www.biorxiv.org/content/10.1...
Connectomic analysis of astrocyte-synapse interactions in the cerebral cortex
Astrocytes, a main type of glia cells in the cortex, provide metabolic support to neurons, and their possible function as a synaptic partner has given rise to the notion of “tripartite” synapses, sugg...
www.biorxiv.org
1 3
helenelab.bsky.social
Helene Schmidt @helenelab.bsky.social · May 5
Thanks! This looks like a glia cell to me, but to be sure one would need to follow it a bit to see if the processes are glia like.
1
helenelab.bsky.social
Helene Schmidt @helenelab.bsky.social · Apr 23
Congrats to Eleonora, Maria and Mourat and thanks to scalableminds and @mhlab.bsky.social for incredible support! @ESI_Frankfurt @mpibrain.bsky.social
1
helenelab.bsky.social
Helene Schmidt @helenelab.bsky.social · Apr 23
…and we used this and our other datasets to sample systematically how a mouse’s memory networks are configured synaptically www.biorxiv.org/content/10.1... . Totally stunned by how special CA1 and CA3 are at the synaptic weight level!
Connectomic traces of Hebbian plasticity in the entorhinal-hippocampal system
The key model of how we learn and memorize is Hebbian learning in the hippocampus, via long-term potentiation of synapses, allowing the storage of associations, linkage to places, and their consolidat...
www.biorxiv.org
1 5
helenelab.bsky.social
Helene Schmidt @helenelab.bsky.social · Apr 23
Super happy that our papers #2 and #3 from our 3-person lab just went online on bioRxiv! First large-scale 3D EM dataset from mouse hippocampus CA1 www.biorxiv.org/content/10.1... - check out the beautiful data on webknossos wklink.org/7023 ! …
3 9 38