Thank you for sharing, Cristina!

Thank you so much for attending and sharing our session 🤩
Next time, come say hi 👋

Yeah. Hopefully the group with HFrEF gets some benefit 🤞

Yes @lonniepyne.bsky.social was the presenter! Hopefully he might sneak in to give his thoughts on the matter #ERA25

Also, the last author presented a new meta analysis with ACHIEVE and ALCHEMIST. Considering only studies with low risk of bias, still no evidence of positive effect @hswapnil.medsky.social

So, about that. @pepasolerr.bsky.social asked about stratification by LVEF/echo data. Looks like only a small % had echo at baseline, but during follow up most patients got one. The author said they are going to look into that #ERA25

Sorry, the app might have bugged on me. Are you talking about the Spironolactone trial? This replies are under the sglt2i aki analysis

Me neither, but the study was well designed to answer the question. Regarding HF, I don't think so, but they basically used all the Empagliflozin trials for the analysis

Prof Anders made a case for the (im)balance between workload (hyperfiltration) and nephron mass as the key interaction

DM is a risk factor - there are no diabetic HF or diabetic cerebral vascular disease. Most cases are probably multifactorial

HTN ckd probably doesnt exist and most are genetic

Wasn't aware of that, thanks! Dr. Walsh mentioned it is already accepted for publication in a major journal #ERA25

Sibeprenlimab in IgA Nephropathy #ERA25
* Data presented is the 9-month reduction in proteinuria

Thanks for letting me know 🙏

Reduce the Workload, save your kidneys #ERA25

I agree.

Clinically it doesn’t hurt to try a flozin if a patient with diabetes or HF is on an MRA and has hyperkalemia since flozins are clearly indicated in that patient population

But don’t bank on them to fix the issue - it’s a small effect even if true!

#ERA25 #NephSky

In a bit more detail... #ERA25

Ah, yes. By the way they presented it looked significant. But, still a small decrease is much better than an increased risk 😁

Yes, the lack of morphological and hemodynamic data about the AVGs was also puzzling #ERA25