Joe Loparo
@joeloparo.bsky.social
230 followers
96 following
9 posts
Professor of Biological Chemistry & Molecular Pharmacology @HMS using single-molecule approaches to understand biological mechanism. DSB repair, TLS and bacterial cell wall
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Reposted by Joe Loparo
Reposted by Joe Loparo
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Reposted by Joe Loparo
Shana Gadarian
@sgadarian.bsky.social
· May 20
Joe Loparo
@joeloparo.bsky.social
· May 21
Joe Loparo
@joeloparo.bsky.social
· May 21
Reposted by Joe Loparo
Joe Loparo
@joeloparo.bsky.social
· Feb 1
Reposted by Joe Loparo
Joe Loparo
@joeloparo.bsky.social
· Dec 24
MreC-MreD structure reveals a multifaceted interface that controls MreC conformation
The peptidoglycan (PG) cell wall is critical for bacterial growth and survival and is a primary antibiotic target. MreD is an essential accessory factor of the Rod complex, which carries out PG synthe...
www.biorxiv.org
Joe Loparo
@joeloparo.bsky.social
· Dec 24
Allosteric activation of cell wall synthesis during bacterial growth - Nature Communications
Coordination of cell wall assembly is critical for bacterial morphology and survival. Here, the authors show that activation of cell wall synthesis by the Rod complex is regulated by the structural dy...
www.nature.com
Joe Loparo
@joeloparo.bsky.social
· Dec 24