The bald, subterranean rats are the world's longest-lived rodent.

Deep beneath the ocean's surface, a groundbreaking DNA study reveals that the deep sea is far more globally connected than once thought. By analyzing thousands of brittle stars preserved in museum col...

Researchers reveal that cicadas time their early morning chorus to a precise light threshold, offering new insights into collective animal behaviour.

Some ant species that can only survive indoors in cooler regions could begin to move outdoors due to climate change, according to a new U of T Scarborough study.   The study, published in the journal ...

Anthony Nichols Lab

Rosalind Franklin never lived to see the full impact of her discoveries. She didn’t witness how her work on DNA would revolutionise biology, nor did she witness the impact she would have in…

New studies from Germany and Hong Kong pinpoint specific sources of light pollution keeping our cities excessively bright at night.

Conservation lands and human-affected biomes with quality habitats are vital for the persistence of carnivores worldwide.

Hallmarks of multicellular eukaryotic genome organization are chromosome territories, compartments, and loop-extrusion-mediated structures, including TADs. However, these are mainly observed in model organisms, and most eukaryotes remain unexplored. Using Hi-C in the silkworm Bombyx mori we discover a novel chromatin folding structure, compartment S, which is “secluded” from the rest of the chromosome. This compartment exhibits loop extrusion features and a unique genetic and epigenetic landscape, and it localizes towards the periphery of chromosome territories. While euchromatin and heterochromatin display preferential compartmental contacts, S domains are remarkably devoid of contacts with other regions, including with other S domains. Polymer simulations show that this contact pattern can only be explained by high loop-extrusion activity within compartment S, combined with low extrusion elsewhere through the genome. This unique, targeted extrusion represents a novel phenomenon and underscores how evolutionarily conserved mechanisms—compartmentalization and loop extrusion—can be repurposed to create new 3D genome architectures. ### Competing Interest Statement The authors have declared no competing interest.

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The David H. Smith Postdoctoral Conservation Research Fellowship Program provides a unique opportunity for early-career conservation scientists to pursue novel research, build professional networks,…

This weekend, tens of thousands of Estonians from every corner of the country will flock to the Tallinn Song Festival Grounds for the 28th laulupidu (Song Festival). ERR News outlines the history of t...

Species classified as Critically Endangered are at greatest risk of extinction, and their preservation and recovery are crucial to meeting global biodiversity aims. This Review assesses the geographic...

Fonds Zukunft Österreich (FZÖ) is providing €10 million in funding for an academy program to bring postdocs from the USA to Austria ++ Faßmann: “The right signal in these turbulent times”