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julian-buissant.bsky.social
Julian Buissant des Amorie
@julian-buissant.bsky.social
42 followers 59 following 1 posts
PhD candidate in Snippert lab at UMCU Utrecht. Working on intestinal tuft cells and colorectal cancer using organoids.
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julian-buissant.bsky.social
Julian Buissant des Amorie @julian-buissant.bsky.social · Dec 3
Very happy that our tuft cell story is now on BioRxiv! If you want to know how to induce mature tuft cell phenotypes in organoids check out the preprint
hugosnippert.bsky.social
Snippert lab @hugosnippert.bsky.social · Dec 1
New work on #tuft cells, rare guardians of our #gut against invaders. How they work is not known. We show that intestinal tuft types 1&2 are sequentially expressed phenotypes during differentiation. And…we can now generate mature immune-related tuft-2’s in #organoids for more 🔬🧫🧬🔥
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Mature tuft cell phenotypes are sequentially expressed along the intestinal crypt-villus axis following cytokine-induced tuft cell hyperplasia
Intestinal tuft cells are epithelial sentinels that trigger host defense upon detection of parasite-derived compounds. While representing interesting targets for immunomodulatory therapies in inflamma...
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