Dr. Tobias Karakach
@karakachlab.bsky.social
Assistant Professor; Scientist; Stoic; Humanist;
Neither an unreasonable conservative idiot nor a liberal freak.
Neither an unreasonable conservative idiot nor a liberal freak.
Proof?
• Improved breast cancer subtyping vs PAM50
• Links to survival + tumor mutational burden
• Free R package + web app for the community
👉 www.karakachlab.org/software/int...
• Improved breast cancer subtyping vs PAM50
• Links to survival + tumor mutational burden
• Free R package + web app for the community
👉 www.karakachlab.org/software/int...
September 21, 2025 at 5:23 PM
Proof?
• Improved breast cancer subtyping vs PAM50
• Links to survival + tumor mutational burden
• Free R package + web app for the community
👉 www.karakachlab.org/software/int...
• Improved breast cancer subtyping vs PAM50
• Links to survival + tumor mutational burden
• Free R package + web app for the community
👉 www.karakachlab.org/software/int...
The solution: kPPA-CART
It digs into those low-signal regions, integrates transcriptomics, proteomics & methylation data, and finds real biological meaning others miss.
It digs into those low-signal regions, integrates transcriptomics, proteomics & methylation data, and finds real biological meaning others miss.
September 21, 2025 at 5:23 PM
The solution: kPPA-CART
It digs into those low-signal regions, integrates transcriptomics, proteomics & methylation data, and finds real biological meaning others miss.
It digs into those low-signal regions, integrates transcriptomics, proteomics & methylation data, and finds real biological meaning others miss.
What’s the problem? 🤔
Most computational tools in bioinformatics only detect strong, obvious signals. Subtle, low-intensity features (the ones that really matter for biology) get lost in the noise.
Most computational tools in bioinformatics only detect strong, obvious signals. Subtle, low-intensity features (the ones that really matter for biology) get lost in the noise.
September 21, 2025 at 5:22 PM
What’s the problem? 🤔
Most computational tools in bioinformatics only detect strong, obvious signals. Subtle, low-intensity features (the ones that really matter for biology) get lost in the noise.
Most computational tools in bioinformatics only detect strong, obvious signals. Subtle, low-intensity features (the ones that really matter for biology) get lost in the noise.
Like Dj Khalid, another one from the KarakachLab!
We just dropped kPPA-CART in @narjournal.bsky.social, a new machine learning method that finds hidden signals in messy multi-omics data. From kidney aging 🧬 to breast cancer 🎗️, it uncovers patterns others miss.
doi.org/10.1093/nar/...
We just dropped kPPA-CART in @narjournal.bsky.social, a new machine learning method that finds hidden signals in messy multi-omics data. From kidney aging 🧬 to breast cancer 🎗️, it uncovers patterns others miss.
doi.org/10.1093/nar/...
September 21, 2025 at 5:19 PM
Like Dj Khalid, another one from the KarakachLab!
We just dropped kPPA-CART in @narjournal.bsky.social, a new machine learning method that finds hidden signals in messy multi-omics data. From kidney aging 🧬 to breast cancer 🎗️, it uncovers patterns others miss.
doi.org/10.1093/nar/...
We just dropped kPPA-CART in @narjournal.bsky.social, a new machine learning method that finds hidden signals in messy multi-omics data. From kidney aging 🧬 to breast cancer 🎗️, it uncovers patterns others miss.
doi.org/10.1093/nar/...
Reposted by Dr. Tobias Karakach
August 25, 2025 at 4:18 PM
Hey @dalhousieu.bsky.social, does this qualify as an own goal?
August 26, 2025 at 12:00 PM
Hey @dalhousieu.bsky.social, does this qualify as an own goal?
Reposted by Dr. Tobias Karakach
I gave a symposium talk at the European Society for Evolutionary Biology 2025 (#eseb2025) meeting last week and this was my title slide showcasing how I was speaking as an independent scientist because @dalhousieu.bsky.social @dalhousie.bsky.social has locked us out.
August 25, 2025 at 12:09 PM
I gave a symposium talk at the European Society for Evolutionary Biology 2025 (#eseb2025) meeting last week and this was my title slide showcasing how I was speaking as an independent scientist because @dalhousieu.bsky.social @dalhousie.bsky.social has locked us out.
Reposted by Dr. Tobias Karakach
All welcome to join DFA's 1st rally in 23 years! In front of the Killam Library, Friday August 22 at 12 noon, half an hour only. See you there! Help us to #KeepDalStrong @ansut.bsky.social @caut.bsky.social @cupe3912.bsky.social @nsgeu.bsky.social
August 21, 2025 at 12:57 PM
All welcome to join DFA's 1st rally in 23 years! In front of the Killam Library, Friday August 22 at 12 noon, half an hour only. See you there! Help us to #KeepDalStrong @ansut.bsky.social @caut.bsky.social @cupe3912.bsky.social @nsgeu.bsky.social
Reposted by Dr. Tobias Karakach
Here’s where we stand:
My union moved on salary and was willing to talk: Dal mgmnt was not interested
My union offered to find ways to save money: Mgmnt said no.
My union wanted to work together to build new child care: Mgmnt didn’t care.
Let’s #KeepDalStrong, we said. No, they replied.
My union moved on salary and was willing to talk: Dal mgmnt was not interested
My union offered to find ways to save money: Mgmnt said no.
My union wanted to work together to build new child care: Mgmnt didn’t care.
Let’s #KeepDalStrong, we said. No, they replied.
August 20, 2025 at 12:13 AM
Here’s where we stand:
My union moved on salary and was willing to talk: Dal mgmnt was not interested
My union offered to find ways to save money: Mgmnt said no.
My union wanted to work together to build new child care: Mgmnt didn’t care.
Let’s #KeepDalStrong, we said. No, they replied.
My union moved on salary and was willing to talk: Dal mgmnt was not interested
My union offered to find ways to save money: Mgmnt said no.
My union wanted to work together to build new child care: Mgmnt didn’t care.
Let’s #KeepDalStrong, we said. No, they replied.
Reposted by Dr. Tobias Karakach
The last post in our series re: the Aug 11 letter from @dalhousieu.bsky.social Pres Brooks to DFA Pres Westwood. RESPECT, VALUE, RECOGNITION of faculty have NOT been reflected at the table. Dal must do better to #KeepDalStrong. @cupe3912.bsky.social @ansut.bsky.social @caut.bsky.social
August 17, 2025 at 5:05 PM
The last post in our series re: the Aug 11 letter from @dalhousieu.bsky.social Pres Brooks to DFA Pres Westwood. RESPECT, VALUE, RECOGNITION of faculty have NOT been reflected at the table. Dal must do better to #KeepDalStrong. @cupe3912.bsky.social @ansut.bsky.social @caut.bsky.social
Reposted by Dr. Tobias Karakach
Struggling to make ends meet, many early career faculty need second jobs or side-hustles to support their families. And @dalhousieu.bsky.social - the largest university in Atlantic Canada - thinks a 2% wage increase is acceptable? Think again. #KeepDalStrong @caut.bsky.social @ansut.bsky.social
August 16, 2025 at 1:21 PM
Struggling to make ends meet, many early career faculty need second jobs or side-hustles to support their families. And @dalhousieu.bsky.social - the largest university in Atlantic Canada - thinks a 2% wage increase is acceptable? Think again. #KeepDalStrong @caut.bsky.social @ansut.bsky.social
…lunar eclipse as seen from the karakach residence at 4:12 on pie day.
March 15, 2025 at 12:48 AM
…lunar eclipse as seen from the karakach residence at 4:12 on pie day.
Reposted by Dr. Tobias Karakach
This is a no-brainer: a Granny who wants to volunteer at a school lunch program has to get a security clearance.
And yet Pierre Poilievre who lives in a 19-room mansion funded by the taxpayer refuses or can't get a security clearance.
Something stinks here.
www.thestar.com/politics/fed...
And yet Pierre Poilievre who lives in a 19-room mansion funded by the taxpayer refuses or can't get a security clearance.
Something stinks here.
www.thestar.com/politics/fed...
Pierre Poilievre will no longer receive security briefing from top spy agency
The Conservative leader has argued that he won't be muzzled by secrecy constraints that accompany security clearances.
www.thestar.com
January 29, 2025 at 1:13 AM
This is a no-brainer: a Granny who wants to volunteer at a school lunch program has to get a security clearance.
And yet Pierre Poilievre who lives in a 19-room mansion funded by the taxpayer refuses or can't get a security clearance.
Something stinks here.
www.thestar.com/politics/fed...
And yet Pierre Poilievre who lives in a 19-room mansion funded by the taxpayer refuses or can't get a security clearance.
Something stinks here.
www.thestar.com/politics/fed...
Reposted by Dr. Tobias Karakach
Every time you open your social media feed, you're bombarded with headlines, statistics, and claims that could reshape your worldview.
The terrifying part?
And many of us can't tell which of these are true anymore.
But the consequences are reshaping entire democracies.
The terrifying part?
And many of us can't tell which of these are true anymore.
But the consequences are reshaping entire democracies.
January 8, 2025 at 4:00 PM
Every time you open your social media feed, you're bombarded with headlines, statistics, and claims that could reshape your worldview.
The terrifying part?
And many of us can't tell which of these are true anymore.
But the consequences are reshaping entire democracies.
The terrifying part?
And many of us can't tell which of these are true anymore.
But the consequences are reshaping entire democracies.
Reposted by Dr. Tobias Karakach
Mostly fine today; a few lingering flurries this am esply Ann. Valley.
An intense storm over NL Sunday spreads snow & very strong north winds into PEI & E NS. Avoid travel esply in Inverness-Victoria CB in blizzard conditions.
Prepare for outages. Ugh.
Gradually eases off Monday
An intense storm over NL Sunday spreads snow & very strong north winds into PEI & E NS. Avoid travel esply in Inverness-Victoria CB in blizzard conditions.
Prepare for outages. Ugh.
Gradually eases off Monday
January 4, 2025 at 12:12 PM
Mostly fine today; a few lingering flurries this am esply Ann. Valley.
An intense storm over NL Sunday spreads snow & very strong north winds into PEI & E NS. Avoid travel esply in Inverness-Victoria CB in blizzard conditions.
Prepare for outages. Ugh.
Gradually eases off Monday
An intense storm over NL Sunday spreads snow & very strong north winds into PEI & E NS. Avoid travel esply in Inverness-Victoria CB in blizzard conditions.
Prepare for outages. Ugh.
Gradually eases off Monday