Mirdametinib reduced fear responses & ERK phosphorylation in the amygdala. When combined with DCS+ prediction error, it even disrupted stronger memories. This offers hope: traumatic memories may not be forever. With the right tools/timing, they can be rewritten. #Trauma #PTSD

Raut et al. (2024) used Actimetrics' FreezeFrame & Fear Conditioning Chambers to show reactivating a fear memory + giving the MEK inhibitor mirdametinib could weaken traumatic memory.

Fear Conditioning Chamber
bit.ly/actimetrics-...

FreezeFrame
bit.ly/freezeframe-...

Whether exploring the speed of thought or the precision of movement, MOART gives you the tools to measure what truly matters. #humanperformance #cognition #research

Use MOART to investigate:
🔹#Neuroscience and cognitive processing
🔹Executive function and #attention
🔹Sensorimotor performance

Test options include:
🔹Simple & choice RT
🔹Go / No Go & movement tasks
🔹Tapping & dual-task (w/ PsymLab software)

At the core is #FreezeFrame, the first video-based software for fear conditioning. It offers human-level sensitivity with automated scalability (now the gold standard in freezing behavior analysis). 📊 #BehavioralNeuroscience #Optogenetics

Designed for efficiency:
🔹 Supports up to 4 test stations on 1 computer
🔹 Shocker, speaker, and house light included
🔹 Optional cue light for visual stimuli
🔹 Flexible camera mount for top or rear placement (ideal for optogenetics) #FearConditioning