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Reposted by Jenni Laitila, PhD

Myofin Research Group @myofinlab.bsky.social · 2d

Our team is excited to connect - come find us at the @worldmusclesociety.org congress. 🇦🇹 Let’s talk science, collaboration, and future ideas! 🧬🤝💡
#WMS2025

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Reposted by Jenni Laitila, PhD

Myofin Research Group @myofinlab.bsky.social · 3d

During the week in between EMC and WMS, Jenni and Fanny visited the de Winter, Ottenheijm and Kirby labs at the Department of Physiology at Amsterdam UMC for an intro to single fibre mechanics and some interesting imaging techniques. 🇳🇱🔬 (1/2)

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Reposted by Jenni Laitila, PhD

Jaakko Sarparanta @jaakkosarparanta.bsky.social · 10d

Two years from today #Helsinki and #Finlandiahall will welcome #WMS2027, the annual congress of @worldmusclesociety.org. Save the date!

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Jenni Laitila, PhD @laitilajenni.bsky.social · 18d

Surrounded by my kind of people 💪🔬🧫 #EMC2025 #nerd @myofinlab.bsky.social @folkhalsanresearch.bsky.social

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Reposted by Jenni Laitila, PhD

Myofin Research Group @myofinlab.bsky.social · 18d

Greetings from the opening ceremony of the European Muscle Conference 2025! 🇳🇱 #EMC2025 #EuropeanMuscleConference

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Reposted by Jenni Laitila, PhD

Myofin Research Group @myofinlab.bsky.social · 19d

Our team is excited to connect - come find Jenni, Jaakko and Fanny at the European Muscle Conference. 🇳🇱 Let’s talk science, collaboration, and future ideas! 🧬🤝💡
#EMC2025 #EuropeanMuscleConference

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Reposted by Jenni Laitila, PhD

Myofin Research Group @myofinlab.bsky.social · 20d

Myofin ”Summer” meeting in Nuuksio 🧬💡🌲. A couple of days filled with insightful scientific talks and interactive discussions on current and upcoming projects! On Wednesday evening it was sauna time and we grilled sausage over the fire 🧖🔥🪵.

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Jenni Laitila, PhD @laitilajenni.bsky.social · Jul 11

When you get a feeling that someone's watching.. Our summer student making great progress with our AI analyses ❤️💪🔬 #muscleresearch #raredisease #myoblue @myofinlab.bsky.social @folkhalsanresearch.bsky.social

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Jenni Laitila, PhD @laitilajenni.bsky.social · Jul 5

So many reasons to celebrate! And these guys are always up for some bubbles 🎉🥂💪🔬 @myofinlab.bsky.social @folkhalsanresearch.bsky.social

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Reposted by Jenni Laitila, PhD

Folkhälsan Research Center @folkhalsanresearch.bsky.social · Jun 25

Elina Engberg and Jenni Laitila are new Academy Research Fellows, and a joint project on the oral microbiome in health and disease received Academy Project Funding.
@elinaengberg.bsky.social @laitilajenni.bsky.social @myofinlab.bsky.social @fin-hit.bsky.social
research.folkhalsan.fi/news-article...

Two new Academy Research Fellows and one joint Academy Project at Folkhälsan Research Center receive funding

The Research Council of Finland’s Scientific Council for Biosciences, Health and the Environment has granted funding to two new Academy Research Fellows at Folkhälsan Research Center. Elina Engberg an...

research.folkhalsan.fi

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Reposted by Jenni Laitila, PhD

Fanny Rostedt, MSc @rostedtfanny.bsky.social · Jun 18

Congrats to the best supervisor @laitilajenni.bsky.social ! Big achievement ♥️💪🏻🧬

Myofin Research Group @myofinlab.bsky.social · Jun 17

We are very grateful to the Research Council of Finland (Suomen Akatemia) for funding our research on neuromuscular disorders. Thank you / Kiitos / Tack! 💙

Jenni has been awarded an Academy Research Fellowship, which entails a 4-year grant. Jenni shares what the grant will be used for 👇: (1/4)

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Jenni Laitila, PhD @laitilajenni.bsky.social · Jun 17

Thank you so much! Our work together continues 😍🙌

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Jenni Laitila, PhD @laitilajenni.bsky.social · Jun 17

Grateful and honoured 🙏🔬💪

Myofin Research Group @myofinlab.bsky.social · Jun 17

We are very grateful to the Research Council of Finland (Suomen Akatemia) for funding our research on neuromuscular disorders. Thank you / Kiitos / Tack! 💙

Jenni has been awarded an Academy Research Fellowship, which entails a 4-year grant. Jenni shares what the grant will be used for 👇: (1/4)

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Reposted by Jenni Laitila, PhD

Myofin Research Group @myofinlab.bsky.social · Jun 12

Go team go! ⚽️🙌🏻 @folkhalsanresearch.bsky.social

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Jenni Laitila, PhD @laitilajenni.bsky.social · May 24

Our talented young investigators, what an amazing day! Excellent talks, beautiful science and great discussions 💪🔬 @myofinlab.bsky.social @folkhalsanresearch.bsky.social

Myofin Research Group @myofinlab.bsky.social · May 23

Yesterday we had the first (but not last) Myofin Young Investigators Day! 🌟 The day was filled with great presentations from our young researchers and out-of-the-box questions from the audience.

Thank you to Jenni, Veronica and Marco for organizing the event! 💙

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Jenni Laitila, PhD @laitilajenni.bsky.social · May 23

Another NM paper quite fittingly published during #NMAwarenessMonth by our team at @myofinlab.bsky.social @folkhalsanresearch.bsky.social
💪🔬💙

Myofin Research Group @myofinlab.bsky.social · May 23

🚨Publication alert!🚨

doi.org/10.1177/2214...

First author Milla’s summary of the article:

”The objective of this study was to identify and further investigate the causative genetic variant in a patient with lethal nemaline myopathy.” (1/6)
#MyoBlue

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Jenni Laitila, PhD @laitilajenni.bsky.social · May 8

This article was very fittingly published during the Nemaline Myopathy Awareness Month – please take a look at buildingstrength.org for more information on how to get involved 💙
#NMAwarenessMonth #NemalineMyopathy #AFBS (5/5)

A Foundation Building Strength for Nemaline Myopathy

We are the leader in funding Nemaline Myopathy research, dedicated to finding treatments for the rare muscle disease.

buildingstrength.org

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Jenni Laitila, PhD @laitilajenni.bsky.social · May 8

💡 This suggests that abnormal troponin T behaviour leads to hyper-contractility – and opens the door to potential treatments targeting this overactivity. (4/5)

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Jenni Laitila, PhD @laitilajenni.bsky.social · May 8

🔬 Our findings show that these variants change how troponin T1 protein is expressed and modified, making muscle fibres more sensitive to calcium and the thin filaments more compliant. (3/5)

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Jenni Laitila, PhD @laitilajenni.bsky.social · May 8

🧬 We investigated how pathogenic variants in the TNNT1 gene disrupt skeletal muscle function in nemaline myopathy, causing skeletal muscle weakness/contractures. No therapeutic treatment exists. (2/5)

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Jenni Laitila, PhD @laitilajenni.bsky.social · May 8

Excited to share our latest work! This was one of my main projects, and a huge collaborative effort during my postdoc in @droch.bsky.social lab at University of Copenhagen - many thanks to all the co-authors and @novo-nordisk.bsky.social 💪🔬 (1/5)

Pathogenic TNNT1 variants are associated with aberrant thin filament compliance and myofibre hyper‐contractility

Abstract figure legend Graphical representation of the main results. The cartoon indicates that, in the presence of TNNT1 variants, the thin filament is more compliant, and more easily activated lead...

physoc.onlinelibrary.wiley.com

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Jenni Laitila, PhD @laitilajenni.bsky.social · May 7

Just another day in the lab 😂

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Jenni Laitila, PhD @laitilajenni.bsky.social · May 6

Another beautiful collaboration 🔬💪 Proof-of-principle of getting both functional and proteomics data from a single myofiber - even from our tiny nemaline myopathy ones! Thanks for all the fun times in the lab @robertseaborne.bsky.social

Robert Seaborne @robertseaborne.bsky.social · May 5

Integrated single-cell functional-proteomic profiling reveals a shift in myofibre specificity in human nemaline myopathy: A proof-of-principle study

Another collab between the labs @droch.bsky.social @adeshmukh.bsky.social

physoc.onlinelibrary.wiley.com/doi/10.1113/...

Integrated single‐cell functional‐proteomic profiling reveals a shift in myofibre specificity in human nemaline myopathy: A proof‐of‐principle study

Abstract figure legend SMPFO uniquely develops data relating to the biophysical state of the sarcomeric protein, alongside global proteome profiling, on a single myofibre basis. Using this approach w...

physoc.onlinelibrary.wiley.com

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Jenni Laitila, PhD @laitilajenni.bsky.social · Apr 24

So proud of these two superstars and the entire Myofin group at the FHRC Scientific Days 💪🔬

Another well deserved poster prize for @rostedtfanny.bsky.social 🤩🙌

@myofinlab.bsky.social @folkhalsanresearch.bsky.social

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Reposted by Jenni Laitila, PhD

Myofin Research Group @myofinlab.bsky.social · Apr 24

We had the pleasure to attend the Scientific Days organized by @folkhalsanresearch.bsky.social at Haikko. Fanny (single-fibre studies) and Milla (nanopore-sequencing) took part in the poster pitching session and had posters on display … (1/3)

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