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Reposted by Laura Wisse

Julie Ottoy @ottoyjulie.bsky.social · 29d

🔥Recent advances in #neuroimaging of #Alzheimers disease 🧠✨

dx.doi.org/10.1002/alz....

➡️ Valuable resource for both researchers & clinicians!
➡️ ATNIV biomarkers, staging, connectomics & more
➡️ Plus: how are sex & country represented in first/last authorship?

@istaart.bsky.social Neuroimaging PIA

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biofinder.bsky.social @biofinder.bsky.social · Aug 5

🚨This study led by @anikawuestefeld.bsky.social aims to provide a more granular understanding of how tau pathology leads to specific cognitive decline in Alzheimer's disease. 🧠 Out now in Alzheimer’s & Dementia! Read it here: doi.org/10.1002/alz....
🧵👇

Tau, atrophy, and domain‐specific cognitive impairment in typical Alzheimer's disease

INTRODUCTION A granular understanding of the mechanisms linking tau pathology to cognitive decline in Alzheimer's disease is crucial. We investigate mediating effects of medial temporal lobe (MTL) a...

doi.org

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Anika Wuestefeld, PhD @anikawuestefeld.bsky.social · Aug 5

Really happy that the final paper of my PhD is out now!
It was great to work on this project with Dave Wolk (@picslupenn.bsky.social) & @lemwisse.bsky.social and all others involved!
See below for more information! 👇

biofinder.bsky.social @biofinder.bsky.social · Aug 5

🚨This study led by @anikawuestefeld.bsky.social aims to provide a more granular understanding of how tau pathology leads to specific cognitive decline in Alzheimer's disease. 🧠 Out now in Alzheimer’s & Dementia! Read it here: doi.org/10.1002/alz....
🧵👇

Tau, atrophy, and domain‐specific cognitive impairment in typical Alzheimer's disease

INTRODUCTION A granular understanding of the mechanisms linking tau pathology to cognitive decline in Alzheimer's disease is crucial. We investigate mediating effects of medial temporal lobe (MTL) a...

doi.org

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Laura Wisse @lemwisse.bsky.social · Jul 24

So excited to attend #AAIC25 in person again this year! Looking forward to a week of exciting science to #ENDALZ.

Very proud of my trainees who will be presenting their work - don't forget to tune in!

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Rosanna Olsen @rosannaolsen.bsky.social · Jun 24

This is your quarterly reminder that the hippocampus is a cortical (not subcortical) structure! Nicola Palomero-Gallagher underscored this point during our #OHBM2025 educational course!

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Anne Urai 🟥 @anne-urai.bsky.social · Jun 20

Come work in my dept! We are hiring a lecturer in psychology (ideally speaking Dutch) @leidenpsychology.bsky.social

www.academictransfer.com/en/jobs/3529...

Docent Psychologie

De Sectie Cognitieve Psychologie van het Instituut Psychologie van de Faculteit Sociale Wetenschappen heeft een vacature voor Docent Psychologie Dit ga je doen Als docent psychologie ga je onderwijs v...

www.academictransfer.com

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Laura Wisse @lemwisse.bsky.social · Jun 13

Very proud of @anikawuestefeld.bsky.social for finishing her PhD thesis on the medial temporal lobe in aging and dementia! Following Swedish tradition, the thesis is now nailed to the wall.... last step before the defense next week. I have no doubt she will nail this too!

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itksnap.bsky.social @itksnap.bsky.social · Jun 5

youtu.be/gpQ19OPUm34

New integration with nnInteractive (github.com/MIC-DKFZ/nnI...) in ITK-SNAP 4.4.0-alpha2 (itksnap.org) lets you turn scribbles into 3D segmentations in seconds. All thanks to an amazing new model from Fabian Isensee and colleagues at @helmholtzimaging.bsky.social!

Demo of new Deep Learning Segmentation in ITK-SNAP 4.4

YouTube video by ITK-SNAP

youtu.be

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Laura Wisse @lemwisse.bsky.social · Jun 3

Also check out my commentary with @relajoie.bsky.social: shorturl.at/bOTtY

Medial temporal lobe structural changes when Down syndrome and Alzheimer’s disease collide

This scientific commentary refers to ‘Medial temporal lobe atrophy in Down syndrome along the Alzheimer’s disease continuum’ by Buehner et al. (https://doi

shorturl.at

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Laura Wisse @lemwisse.bsky.social · Jun 3

Very important article on Down syndrome and AD by Buehner et al.(shorturl.at/ETFUz) highlighting the non-linear trajectories of structural changes in MTL subregions in patients with Down syndrome & AD and the utility of MTL structural markers for clinical trials and prediction of decline.

Medial temporal lobe atrophy in Down syndrome along the Alzheimer’s disease continuum

Buehner et al. describe progressive structural changes in the medial temporal lobe in association with Alzheimer's disease pathology in 259 adults with Dow

shorturl.at

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emmacoomans.bsky.social @emmacoomans.bsky.social · Apr 28

So excited and honored to be invited to present the opening plenary at #AIC2025 this year in Toronto! 🧠

🙏 I would be very grateful if you could help me gather the most inspiring papers (including your own!) of the past year by completing this ~5min survey: alz.surveymonkey.com/r/923BTQK

Anika Wuestefeld, PhD @anikawuestefeld.bsky.social · Apr 28

🚨Calling all neuroimagers! Help
@emmacoomans.bsky.social shape the opening plenary at #AIC2025 (Toronto, July 26th) "Accomplishments of the Past Year" and share the most impactful neuroimaging research from the past year via this brief survey (~5min) by May 30th.
act.alz.org/site/R?i=eOe...

Neuroimaging PIA: The Past Year (since July 1, 2024) and The Future

Take this survey powered by surveymonkey.com. Create your own surveys for free.

act.alz.org

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Laura Wisse @lemwisse.bsky.social · Apr 25

Woohoo!!

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Robin de Flores @robindeflores.bsky.social · Apr 24

🧠 PhD position available!

Study polypathology in the medial temporal lobe at the Paris Brain Institute with @lemwisse.bsky.social , @nvillain-alz.bsky.social and myself.

This exciting project combines neuroimaging, neuropathology and cognition!

Please share widely 🙏

Laura Wisse @lemwisse.bsky.social · Apr 23

Super excited to announce a PhD position on polypathology in the medial temporal lobe at the Paris Brain Institute together with @nvillain-alz.bsky.social and @robindeflores.bsky.social!

offres.institutducerveau-icm.org/fr/jobs/1935...

Please repost!

Nos super offres || PhD - polypathology in the medial temporal lobe

offres.institutducerveau-icm.org

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Nicolas Villain @nvillain-alz.bsky.social · Apr 23

Exciting opportunity for a PhD position at the @institutducerveau.bsky.social on a European collaborative project under the supervision of medial temporal lobe specialists!
Spread the word!

bsky.app/profile/lemw...

Laura Wisse @lemwisse.bsky.social · Apr 23

Super excited to announce a PhD position on polypathology in the medial temporal lobe at the Paris Brain Institute together with @nvillain-alz.bsky.social and @robindeflores.bsky.social!

offres.institutducerveau-icm.org/fr/jobs/1935...

Please repost!

Nos super offres || PhD - polypathology in the medial temporal lobe

offres.institutducerveau-icm.org

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Laura Wisse @lemwisse.bsky.social · Apr 23

Very grateful for the funding of this project provided by @alzheimer-recherche.org!

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Laura Wisse @lemwisse.bsky.social · Apr 23

Super excited to announce a PhD position on polypathology in the medial temporal lobe at the Paris Brain Institute together with @nvillain-alz.bsky.social and @robindeflores.bsky.social!

offres.institutducerveau-icm.org/fr/jobs/1935...

Please repost!

Nos super offres || PhD - polypathology in the medial temporal lobe

offres.institutducerveau-icm.org

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Masud Husain @masudhusain.bsky.social · Mar 6

Why academia is sleepwalking into self-destruction. My editorial @brain1878.bsky.social If you agree with the sentiments please repost. It's important for all our sakes to stop the madness
academic.oup.com/brain/articl...

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Reposted by Laura Wisse

Jace D. Flatt, PhD, MPH (They/He) @jaceflatt.bsky.social · Mar 6

If judge don’t stop, NIH employees review new/ongoing projects:

Cat 1: solely support DEI activities. CUT

Cat 2: partially support. Renegotiate or CUT

Cat 3: don’t support but some DEI language. Cont./cut language in app/progress reports.

Cat 4: don’t support any. Cont & DEI not in reports.

Jace D. Flatt, PhD, MPH (They/He) @jaceflatt.bsky.social · Mar 6

www.nature.com/articles/d41...

Exclusive: NIH to terminate hundreds of active research grants

Studies that touch on LGBT+ health, gender identity and DEI in the biomedical workforce could be terminated, according to documents obtained by Nature.

www.nature.com

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Laura Wisse @lemwisse.bsky.social · Feb 26

Excited that is also available in new version of ASHS including not only anterior MTL cortical regions but also the amygdala!
www.nitrc.org/frs/shownote...

The amygdala protocol developed by @anikawuestefeld.bsky.social is described in the supplements of alzres.biomedcentral.com/articles/10....

Medial temporal lobe atrophy patterns in early-versus late-onset amnestic Alzheimer’s disease - Alzheimer's Research & Therapy

Background The medial temporal lobe (MTL) is hypothesized to be relatively spared in early-onset Alzheimer’s disease (EOAD). Yet, detailed examination of MTL subfields and drivers of atrophy in amnest...

alzres.biomedcentral.com

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Laura Wisse @lemwisse.bsky.social · Feb 26

Beautiful work by Niyousha Sadeghpour developing a manual segmentation protocol for the anterior MTL cortex, important in AD and LATE! Grounded in a large set of annotated histology sections and postmortem MRI scans, labelled by the late Ricardo Insausti & his team.

www.biorxiv.org/content/10.1...

Developing an anatomically valid segmentation protocol for anterior regions of the medial temporal lobe for neurodegenerative diseases

Background The anterior portion of the medial temporal lobe (MTL) is one of the first regions targeted by pathology in sporadic Alzheimer’s disease (AD) and Limbic-predominant Age-related TDP-43 Encep...

www.biorxiv.org

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Laura Wisse @lemwisse.bsky.social · Feb 25

Also big thanks to coauthors @anikawuestefeld.bsky.social @drneurochic.bsky.social and Bill Jagust!

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Laura Wisse @lemwisse.bsky.social · Feb 24

Lovely collaboration with Renaud La Joie - our review is finally out! Summarizing the role of tau and TDP-43 in medial temporal atrophy in Alzheimer's disease and exploring different hypotheses regarding their potential timing and synergism.

alz-journals.onlinelibrary.wiley.com/doi/10.1002/...

Role of tau versus TDP‐43 pathology on medial temporal lobe atrophy in aging and Alzheimer's disease

Hippocampal atrophy on magnetic resonance imaging is an important biomarker in Alzheimer's disease (AD). While hippocampal atrophy was thought to result from tau tangles in AD, different neuropathol...

alz-journals.onlinelibrary.wiley.com

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Siri Leknes @sirileknes.bsky.social · Feb 19

There are currently three open faculty positions (all levels) in my department (Psychology)
Oslo is a lovely city, modestly sized (600k) but a capital, surrounded by forest and the fjord

We're also a stable democracy with high support of and trust in science

www.sv.uio.no/english/abou...

Jobs and vacancies - Faculty of Social Sciences

Read this story on the University of Oslo's website.

www.sv.uio.no

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Daniel P. Moriarity @dpmoriarity.bsky.social · Feb 10

PA Attorney General: 717-787-3391

Bita Moghaddam @bita137.bsky.social · Feb 10

If you are a NIH funded researcher and your state is not on this list, you need to be calling your AG office

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Reposted by Laura Wisse

Joana B Pereira @joana-b-pereira.bsky.social · Feb 3

I am looking for a Postdoc to work in my group at Karolinska Institute in projects that combine brain imaging with machine learning, genetics & proteomics in aging and neurodegenerative diseases. To apply please go to: ki.varbi.com/en/what:job/... (Deadline: 20.Feb.2025) Please retweet. Thanks!

Brain Connectomics, Pereira's Lab – Joana Pereira's research group

Our group works with brain connectivity, biofluid markers and behavioural measures in aging, neurodegenerative and psychiatric disorders.

ki.se

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