Leon Lotter
@leondlotter.de
780 followers 760 following 65 posts
👨‍💻 MD | PhD candidate 🧠 Neurodevelopment | ADHD | ASD 📊 Multimodal neuroimaging 🏫 INM-7, Research Centre Juelich 🎓 Max Planck School of Cognition 🐮 Vegan 👤 He/him 📷 By N. Brade 🌐 https://leondlotter.de
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Reposted by Leon Lotter
benjaminkay.bsky.social
Ever wondered if your interesting brain-behavior correlation was over- or under-estimated due to head motion, but were afraid to ask? We’ve created a motion impact score for detecting spurious brain-behavior associations, now available in Nature Communications!
doi.org/10.1038/s414...
Reposted by Leon Lotter
bttyeo.bsky.social
1/11 Excited to share our @Naturestudy led by @leonooi.bsky.social @csabaorban.bsky.social @shaoshiz.bsky.social

AI performance is known to scale with logarithm of sample size (Kaplan 2020), but in many domains, sample size can be # participants or # measurements...

doi.org/10.1038/s415...
Reposted by Leon Lotter
deniz-yilmaz.bsky.social
After some time since completing my Master’s thesis, I’m excited to share that our work has now been published! It’s rewarding to see the project come full circle and contribute to the field alongside a fantastic team.
You can read the full article here: doi.org/10.1093/brai...
Published in Brain 🧠
leondlotter.de
Amazing new paper on individual development of E/I balance during adolescence, first-authored by @amnsbr.bsky.social!

Read @ Science Advances: www.science.org/doi/10.1126/...

Bonus: Amin developed a tool to run biophysical network modelling on GPUs – because why shouldn't he?
cubnm.readthedocs.io
Reposted by Leon Lotter
carrisacocuzza.bsky.social
🚨Preprint!🚨 So excited to share my 1st major study as a postdoc at @holmeslab-bhi.bsky.social!🤘

www.biorxiv.org/content/10.1...

Using a transdiagnostic framework, we found that brain network dynamics were able to discriminate individualized psychiatric symptom profiles with high accuracy 🧵1/9👇
Reposted by Leon Lotter
Reposted by Leon Lotter
arc-cogitate.bsky.social
🏁 Big news from #Cogitate!🏁

We’re proud to deliver the first part of our promised open multimodal dataset:
iEEG data from 38 patients across 3 centers, collected under a unified protocol.

📄 Paper: doi.org/10.1038/s415...
📀 Data: www.arc-cogitate.com/data-release
💻 Code: github.com/Cogitate-con...
leondlotter.de
Great work! I wonder (and I guess you deliberately avoided this discussion 😬) what implications this has for fMRI, especially "connectivity", analysis. Do we want to remove this signal, if so, is standard global signal regression sufficient, or does this make the case for dynamic GS regression?
Reposted by Leon Lotter
loiclabache.bsky.social
🚨 New #preprint: The molecular and cellular underpinnings of human brain lateralization

🔗 doi.org/10.1101/2025...

🧠 We identify an acetylcholine-norepinephrine axis underlying functional lateralization, along with mitochondrial and cellular correlates. 🧵1/9👇

#neuroskyence
The molecular and cellular underpinnings of human brain lateralization
Hemispheric specialization is a fundamental characteristic of human brain organization, where most individuals exhibit left-hemisphere dominance for language and right-hemisphere dominance for visuosp...
doi.org
Reposted by Leon Lotter
igor-dgps.bsky.social
🧠🌱 New preprint from the IGOR Sustainability project!

"There is no research on a dead planet"
How can we balance neuroscience, open science, and climate responsibility?

📄 Read our position paper on OSF:
osf.io/preprints/osf/rju75_v1
OSF
osf.io
Reposted by Leon Lotter
jeremymberg.bsky.social
Bluetorial-A dream and a bit of a nightmare

Serving as Editor-in-Chief at Science was fascinating. I greatly enjoyed working with talented and committed editorial, news, graphics, and production staff. But the inside look into scientific publishing and AAAS was also deeply disillusioning.
a cartoon says hey everybody an old man 's talking while bart simpson looks on
ALT: a cartoon says hey everybody an old man 's talking while bart simpson looks on
media.tenor.com
Reposted by Leon Lotter
chirag-mehra.bsky.social
🎉 New Year, New Preprint.

Happy to share the first preprint from my #PhD! 🧠

🤔 TL;DR:
Our findings are relevant to anyone using EEG / MEG functional connectivity analyses. They affect the choice of method when analysing your data.

Check it out and tell me your thoughts: shorturl.at/TD3wc

1/6
Zero-phase-delay connectivity increases the reliability, concordance with structure, and prognostic ability of functional connectivity metrics
Zero-phase-delay synchrony between the activity of distant neural populations has been robustly observed. Nevertheless, contemporary electroencephalography and magnetencephalography functional connect...
www.biorxiv.org
Reposted by Leon Lotter
wiringthebrain.bsky.social
A New Year's rant, for 2025 😊:
Reposted by Leon Lotter
misicbata.bsky.social
The effect of spherical projections on spin tests for brain maps | biorxiv.org/content/10.1...

Spin tests are the de facto null model for map-to-map comparisons in brain imaging. Why don't they perfectly control false positives? @vincebaz.bsky.social explores ⤵️
Reposted by Leon Lotter
bsky.app
Bluesky @bsky.app · Dec 3
Scientists, academics, researchers: We’re excited to share that @altmetric.com is now tracking mentions of your research on Bluesky! 🧪
altmetric.com
There are already many articles for which there is more attention on Bluesky than on other comparable micro-blogging sites, meaning the academic community and the general public have clearly adopted Bluesky as one of its core places to disseminate and discuss new research.

A Place of Joy.
‘A place of joy’: why scientists are joining the rush to Bluesky
Researchers say the social-media platform — an alternative to X — offers more control over the content they see and the people they engage with.: https://www.nature.com/articles/d41586-024-03784-6
Reposted by Leon Lotter
ashley-n-nielsen.bsky.social
New paper out today in PNAS 🎉 demonstrating:
1) an association between social disadvantage & child brain function can be observed as early as birth
2) these alterations are brain-wide, but most pronounced in functional networks & subcortex later linked to childhood adversity

doi.org/10.1073/pnas...
Reposted by Leon Lotter
mcxfrank.bsky.social
Three ManyBabies projects - big collaborative replications of infancy phenomena - wrapped up this year. The first paper came out this fall. I thought I'd take this chance to comment on what I make of the non-replication result. 🧵

bsky.app/profile/laur...
Reposted by Leon Lotter
borismontreal.bsky.social
🍾 Now in press @elife.bsky.social

Multimodal correlates of childhood psychopathology

co-led by @jroyer.bsky.social , Valeria Kebets, @bttyeo.bsky.social & our many fantastic co-authors

🙏 based on the ABCD dataset

👉 elifesciences.org/articles/87992