Lightnews — Scholar-powered news

Lina Meng, PharmD

@linameng.bsky.social

1K followers 280 following 37 posts

ID Pharmacist | Antimicrobial Stewardship Team | Stanford Health Care, CA | #MedEd #handshakestewardship I love pugs, 🏐, and travel, but actually spend most of my free time figuring out parenting of young kids🪇

Posts Media Videos Starter Packs

Pinned

Lina Meng, PharmD @linameng.bsky.social · Nov 16

Hi #IDsky & #PharmSky! 👋 I'm an ABX stewie (formerly critical care) at Stanford:
✨ Passionate about learning from others in ID, ASP, & RX.
🛠️ Love creating tools & education for frontline clinicians.
📚 Started Stanford ABX pearls series and Obesity ABX Guidance

Excited to connect and share ideas!

ABX Pearls

med.stanford.edu

3 2 21

Reposted by Lina Meng, PharmD

Stanford Antimicrobial Safety & Sustainability Program @stanfordasp.bsky.social · 14d

🌟 ABX Pearl of the Day:

❓ Q: Candida only grew in 1/4 bottles. Is this a contaminant?

#IDsky #medsky #meded #pharmsky #skyRX #AMSsky

1 3 7

Reposted by Lina Meng, PharmD

Marisa Holubar, MD MS FIDSA @marisa-holubar.bsky.social · 14d

Yay! Tara's our awesome ASP track fellow this year - so lucky to get to work with her! @stanfordasp.bsky.social @linameng.bsky.social @dhpharmd.bsky.social @polishmd.bsky.social

1 2

Lina Meng, PharmD @linameng.bsky.social · 20d

Risks of ABX overuse greater than benefit? 🤔

Lina Meng, PharmD @linameng.bsky.social · 20d

The same treatment was associated with negative outcomes, including increased hospital readmissions, transfers to the ICU, and longer hospital stays. 🏥

1 1

Lina Meng, PharmD @linameng.bsky.social · 20d

The outcome: After adjustment, empiric broad-spectrum antibiotic treatment was not associated with a lower mortality rate. 🚫

1 1

Lina Meng, PharmD @linameng.bsky.social · 20d

🔎 The findings: In 2,706 moderately ICH patients with pneumonia, MRSA and resistant GNB were rare, found in just 3.5% of cases. 📉

Lina Meng, PharmD @linameng.bsky.social · 20d

Is empiric MRSA and PsA coverage needed for all moderately ICH with pneumonia? A recent study in CID offers a data-driven look.

So what to do? Check out our ABX pearl on which ICH patients are best candidates for expanded empiric ABX coverage in CAP. ✅

#amssky #Idsky #medsky #pharmsky

1 1 4

Reposted by Lina Meng, PharmD

Stanford Antimicrobial Safety & Sustainability Program @stanfordasp.bsky.social · 28d

🌟 ABX Pearl of the Day:

❓ Q: My immunocompromised patient is admitted to the ICU and starting ABX for presumed CAP. Do they need empiric MRSA and Pseudomonas coverage?

#IDsky #medsky #meded #pharmsky #skyRX #AMSsky

1 3 11

Reposted by Lina Meng, PharmD

Stanford Antimicrobial Safety & Sustainability Program @stanfordasp.bsky.social · 21d

🌟 ABX Pearl of the Day:

❓ Q: My patient is growing yeast in blood cultures. Is this Candida?

#IDsky #medsky #meded #pharmsky #skyRX #AMSsky

1 5 6

Lina Meng, PharmD @linameng.bsky.social · Jul 25

Check this-CLSI eliminated gentamicin as tx option for PsA.

"Review of modern PK/PD) data against members of the Enterobacterales and P. aeruginosa demonstrated:

• No safe aminoglycoside dosing regimen was predicted to achieve bacterial 1- or 2-log killing, regardless of the breakpoint applied."

2023 AST: CLSI M100 ED33 Updates | News | CLSI

Learn about updated aminoglycoside breakpoints in CLSI M100, Edition 33, for key pathogens.

clsi.org

Reposted by Lina Meng, PharmD

Antibiotic Steward 🅱️C🆔🅿️🌟 @absteward.bsky.social · Jul 17

🔥Finally published🔥
IDSA Guidelines on the Treatment and Management of Complicated Urinary Tract Infections (cUTI)
#idsky
www.idsociety.org/practice-gui...

2 8 26

Lina Meng, PharmD @linameng.bsky.social · May 23

I'm hoping it's because they were super users at baseline 🤓

Lina Meng, PharmD @linameng.bsky.social · May 22

Implementing microlearning via ABX Pearls emailed to clinicians and trainees weekly at our hospital. 81% reported an impact on their practice, across multiple stewardship domains. 👇🏻

Library here:
med.stanford.edu/bugsanddrugs...

#IDPharmacistsDay #medEd #AMSsky

3 8 26

Lina Meng, PharmD @linameng.bsky.social · May 22

Hi! Lina here from Stanford, CA. I love working with the innovative, bright, open-minded ASP team here @stanfordasp.bsky.social and learning from amazing, dedicated pharmDs/MDs nationally that have propelled ABX stewardship forward tremendously in recent years. #IDpharmacistsday

4 10

Reposted by Lina Meng, PharmD

Sean Ong @seanong.bsky.social · Apr 10

Excited to share our newest paper from my PhD: a post-hoc analysis of the BALANCE trial where we explored heterogeneity of treatment effect (HTE) in duration of antibiotic treatment for patients with bloodstream infection. A thread:

doi.org/10.1016/j.ec...

#IDSky @eclinicalmed.bsky.social

Redirecting

doi.org

2 15 35

Reposted by Lina Meng, PharmD

Stanford Antimicrobial Safety & Sustainability Program @stanfordasp.bsky.social · Apr 18

🌟 ABX Pearl of the Day: Linezolid drug interactions

❓ Q: I'd like to prescribe linezolid but my patient is on serotonergic agents. What is the incidence of serotonin syndrome with this combination?

#IDsky #medsky #meded #pharmsky #skyRX

3 7 16

Reposted by Lina Meng, PharmD

Julie Parsonnet @julieparsonnet.bsky.social · Mar 20

We're looking for a new Division Chief in Adult ID at Stanford. We have a great ID/Medicine family here and the division has been growing by leaps and bounds. We also have great Pedi ID, Micro, Immunology and Transplant teams. Please share!

5 7

Lina Meng, PharmD @linameng.bsky.social · Mar 7

Ongoing UCx stewardship efforts at Stanford 🤝 in partnership with infection control, CAUTI taskforce, micro lab, RNs
✔️ 2017: switch to UA with reflex only of wbc>10
✔️2024: a creation of UCx order panel.
🚧 remove UA/UCx orders from surgery pre-op ordersets?
#IDsky #AMSsky

Stanford Antimicrobial Safety & Sustainability Program @stanfordasp.bsky.social · Mar 7

🔍 Key Points:
-Borderline urine WBC counts (6–10 cells/mL) may reflect dehydration and should be expected in patients with oliguria or anuria.
-Low urine WBC (WBC < 10) almost always excludes the diagnosis of UTI.

1 4

Lina Meng, PharmD @linameng.bsky.social · Jan 22

#idsky #amssky Anyone using Tamiflu after IV peramivir in ICU patients that gain enteral access? Do people trust IV peramivir efficacy in severe/hospitalized flu?
pubmed.ncbi.nlm.nih.gov/39181595/

Lina Meng, PharmD @linameng.bsky.social · Jan 7

I learned about this meropenem/VPA drug interaction the hard way as a new practitioner after unsuccessfully dose titrating VPA for days (and wasting 💰). Fortunately VPA indication was for alcohol withdrawal (non benzo ICU protocol at Stanford), not seizures!

See useful tidbits on this interaction👇

Stanford Antimicrobial Safety & Sustainability Program @stanfordasp.bsky.social · Jan 7

🌟 ABX Pearl of the Day: drug interaction carbapenems + valproic acid

💡 Q: I’d like to start meropenem for an ESBL E. coli infection in my patient who is also on valproic acid (VPA). What should I be aware of?

#IDsky #Medsky #MedEd #PharmSky #SkyRX

1 2

Lina Meng, PharmD @linameng.bsky.social · Nov 26

Yes Epic+beaker. Agh that's tough when you have lab limitations

Lina Meng, PharmD @linameng.bsky.social · Nov 25

For ceftriaxone-R Enterobacterales from blood, our micro report shows MIC but no interpretation. Instead, displays cautionary comment. Chance for ASP-micro lab collab! 🤝

2 5

Lina Meng, PharmD @linameng.bsky.social · Nov 24

Study shared by esteemed👇 on
pyuria cutoff (in elderly♀️)"At a cutoff of 264 leuk/µL, sensitivity and specificity of microscopy were 88% (positive and negative likelihood ratio: 7.2 and 0.1, respectively). The commonly used cutoff of 10 leuk/µL had a poor specificity (36%) and a sensitivity of 100%."

Angela Huttner @angelahuttner.bsky.social · Nov 23

Meant to share this study by @merellambregts.bsky.social's team
@cjcrnich.bsky.social 😊 when you & I were on #Breakpoints we were asked whether there was a pyuria cutoff to help differentiate btw infection & colonization
Here may be one (in elderly ♀️ at least) #IDSky
academic.oup.com/cid/article/...

Current Pyuria Cutoffs Promote Inappropriate Urinary Tract Infection Diagnosis in Older Women

The degree of pyuria can help distinguish urinary tract infection (UTI) in older women from asymptomatic women with and without bacteriuria. We demonstrate

academic.oup.com

1 1

Lina Meng, PharmD @linameng.bsky.social · Nov 23

Thrilled to see @conanmacdougall.bsky.social join! 🌟 Your insights are always spot-on. This graph on new ABX approval is spot on. 😂 So true about the emotional rollercoaster—though here, prescribers don't pay attention to drug cost unless formulary restricted. #IDsky #AMSsky #pharmsky #skyrx

Conan MacDougall @conanmacdougall.bsky.social · Nov 23

2 13

Lina Meng, PharmD @linameng.bsky.social · Nov 22

Love our peds ASP colleagues and their amazing tools! ♥️ One of our ED's go-to favorites is their pediatric Amox-Clav Dosing Guide—because seriously, who can keep track of all those doses and formulations/ratios?

Welcome to Blue Sky! 🌟 #AMSsky #IDsky #pharmsky #skyRX #medsky

2 8