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Marco Saponaro @m-saponaro.bsky.social · 2d

3-year technician position with a possibility of doing a PhD available to study chromatin replication and ubiquitylation using cell free system of Xenopus laevis egg extract. Closing date 28/10/25. Get in touch @agagambus.bsky.social or @m-saponaro.bsky.social for informal inquiries
lnkd.in/etU3yydb

This link will take you to a page that’s not on LinkedIn

lnkd.in

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Reposted by Marco Saponaro

Wendy Bickmore @wbickmor.bsky.social · 28d

Honoured to be in Birmingham to mark Bryan Turner’s retirement- a gentleman and giant of epigenetics.

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Marco Saponaro @m-saponaro.bsky.social · Jul 10

So happy to see this finally out, another collaboration with @agagambus.bsky.social!

Aga Gambus @agagambus.bsky.social · Jul 10

It is finally out 👍😀. Great job of the team (mostly absent from Bsky) and @m-saponaro.bsky.social

CDK-driven phosphorylation of TRAIP is essential for mitotic replisome disassembly and MiDAS url: academic.oup.com/nar/article/...

CDK-driven phosphorylation of TRAIP is essential for mitotic replisome disassembly and MiDAS

Abstract. Disassembly of the replication machinery (replisome) from chromatin is an active process driven by two ubiquitin ligases Cul2LRR1 and TRAIP, whic

academic.oup.com

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Marco Saponaro @m-saponaro.bsky.social · Jul 4

Deadline for submitting abstracts is fast approaching, but there is still time to register for this conference and to present your science!!!

Ferenc Mueller @ferencmueller.bsky.social · Jun 25

The Birmingham Centre for Genome Biology invites you
to join us at our 10th year anniversary conference!
Website and Registration here: shorturl.at/rvJSr
Fantastic speakers, and a very cost-efficient meeting for ECRs and all. Talk slots are available. See you in Brum on 11-12th September 2025!

Reposted by Marco Saponaro

Jessica Blair @jessicamablair.bsky.social · Jun 25

The new University of Birmingham Doctoral school has just launched! Very exciting times for Postgraduate research at the university of Birmingham! www.birmingham.ac.uk/study/postgr...

The University Doctoral School - University of Birmingham

Advance your research career with the University of Birmingham's Doctoral School. Access expert support, funding, and development opportunities

www.birmingham.ac.uk

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Reposted by Marco Saponaro

Eva Petermann @petermannlab.bsky.social · Jun 24

Birmingham Centre for Genome Biology 2025 Anniversary Conference, 11-12 September! This symposium covers DDR and gene regulation. Register here:
uobevents.eventsair.com/birmingham-c...

Home - Birmingham Centre for Genome Biology 2025

BCGB 2025, Birmingham Centre for Genome Biology Conference 2025

uobevents.eventsair.com

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Reposted by Marco Saponaro

Ferenc Mueller @ferencmueller.bsky.social · Jun 25

The Birmingham Centre for Genome Biology invites you
to join us at our 10th year anniversary conference!
Website and Registration here: shorturl.at/rvJSr
Fantastic speakers, and a very cost-efficient meeting for ECRs and all. Talk slots are available. See you in Brum on 11-12th September 2025!

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Reposted by Marco Saponaro

GIIN @genomeiinetwork.bsky.social · May 28

Next Tuesday's webinar will feature @agagambus.bsky.social and @chowdhurylab.bsky.social. Join us on June 3rd at 5PM Rome / 11AM NYC for a lively discussion on DNA replication and repair!
Zoom link: uniroma1.zoom.us/j/95149984403
Become part of our community: docs.google.com/forms/d/e/1F...

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Reposted by Marco Saponaro

Paloma Garcia @pggarcialab.bsky.social · May 8

@unibirmingham.bsky.social

Paloma Garcia @pggarcialab.bsky.social · Apr 19

Our last work on triple negative breast cancer stem cells now in BiorXiv!! Let's hope for a smooth reviewing process!! @m-saponaro.bsky.social @breastcancernow.bsky.social @davieslab-ch3.bsky.social @robclarkelab.bsky.social 😃
www.biorxiv.org/content/10.1...

MYBL2 maintains stemness and promotes theta-mediated end joining in triple negative breast cancer

Triple negative breast cancer (TNBC) has a poor prognosis due to limited treatment options and high metastasis risk. Breast cancer (BC) stem/progenitor cells, also known as tumour initiating cells, ar...

www.biorxiv.org

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Marco Saponaro @m-saponaro.bsky.social · May 8

Come and join us to celebrate the 10th anniversary of the BCGB, with a great selection of international speakers! Very convenient conference, open to anyone interested in the field of genome biology!

Home - Birmingham Centre for Genome Biology 2025

uobevents.eventsair.com

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Reposted by Marco Saponaro

Paloma Garcia @pggarcialab.bsky.social · Apr 19

Our last work on triple negative breast cancer stem cells now in BiorXiv!! Let's hope for a smooth reviewing process!! @m-saponaro.bsky.social @breastcancernow.bsky.social @davieslab-ch3.bsky.social @robclarkelab.bsky.social 😃
www.biorxiv.org/content/10.1...

MYBL2 maintains stemness and promotes theta-mediated end joining in triple negative breast cancer

Triple negative breast cancer (TNBC) has a poor prognosis due to limited treatment options and high metastasis risk. Breast cancer (BC) stem/progenitor cells, also known as tumour initiating cells, ar...

www.biorxiv.org

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Reposted by Marco Saponaro

Ronan Broderick @brodericklab.bsky.social · Jan 31

My lab is #hiring!

I am recruiting for two #Postdoc positions investigating the Alternative Lengthening of Telomeres mechanism.

www.jobs.ac.uk/job/DLO693/r...

www.jobs.ac.uk/job/DLP016/r...

#Telomere #DNAreplication #DNArepair #cancer #glioma #UKRI #MRC #universityofbirmingham #NGS

Research Fellow at University of Birmingham

Discover an exciting academic career path as a Research Fellow at jobs.ac.uk. Don't miss out on this job opportunity - apply today!

www.jobs.ac.uk

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Reposted by Marco Saponaro

Aga Gambus @agagambus.bsky.social · Dec 17

Christmas fun with @m-saponaro.bsky.social lab. It was great to see some past and future members of the lab. Christmas cheer all around 😀

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Marco Saponaro @m-saponaro.bsky.social · Nov 23

Thank you @carmeloferrai.bsky.social !!

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Reposted by Marco Saponaro

bioRxiv Molecular Biology @biorxiv-molbio.bsky.social · Nov 21

RNA Polymerase II subunits overexpressions induce genome instability and deregulate transcription https://www.biorxiv.org/content/10.1101/2024.11.20.622938v1

Independently of the pathways or circuits deregulated in cancer cells, these present altered transcr

www.biorxiv.org

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Reposted by Marco Saponaro

Anna Obenauf @obenaufa.bsky.social · Nov 20

Pls share 🌟Join the IMP as a Group Leader
We are 👀 for a colleague, ready to lead a groundbreaking research program. Enjoy generous funding, outstanding facilities & a vibrant scientific community in one of the world's most livable cities @impvienna.bsky.social
👉https://tinyurl.com/impgl2025

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Marco Saponaro @m-saponaro.bsky.social · Nov 21

What happens when you overexpress one subunit of the RNA Pol II? Well, it depends on the subunit, but all deregulate transcription and induce genome instability @agagambus.bsky.social www.biorxiv.org/content/10.1...

RNA Polymerase II subunits overexpressions induce genome instability and deregulate transcription

Independently of the pathways or circuits deregulated in cancer cells, these present altered transcription patterns, often also direct consequence of deregulation of transcription factors. In this sen...

www.biorxiv.org

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