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Sheila Macrine, PhD @macrinephd.bsky.social · 25d

How are the self, space, and time related? A new study on #depersonalization found feeling disconnected from your body-linked to time slowing down, & feeling detached from the world-linked to time speeding up. @Annaciaunica tinyurl.com/bdh4thdb #Neuroscience #TimePerception #Consciousness

Spatiotemporal disruptions of reality perception in depersonalization

Experiences of time and space are core constituents of the sense of bodily self. Depersonalization (DP) is a condition characterized by distressing feelings of

tinyurl.com

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Sheila Macrine, PhD @macrinephd.bsky.social · 26d

A brain-wide map of decision-making! 🧠 Study reveals how sensory inputs, choices & motor actions are encoded across 279 brain regions. Dataset publicly available
#Neuroscience #BrainMapping #DecisionMaking #OpenScience #BigData #Neuropixels t.co/54Lc3CmYgV

https://www.nature.com/articles/s41586-025-09235-0

t.co

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Sheila Macrine, PhD @macrinephd.bsky.social · Sep 5

What do proteins, animal forms & languages have in common? #Evolution! Unified framework detects evolutionary leaps #branching across #molecular, #morphological, and #cultural scales onlinelibrary.wiley.com/doi/epdf/10....
#Genomics #Adaptation
#ComputationalBiology #Biology

Chameleonic Nature of Aβ: Implications for Alzheimer's and Other Amyloid Diseases

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onlinelibrary.wiley.com

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Sheila Macrine, PhD @macrinephd.bsky.social · Sep 5

New research calls an Alzheimer's protein "chameleon-like." 🦎 It shape-shifts to form toxic plaques, but this same flexibility also allows the plaques to break apart. onlinelibrary.wiley.com/doi/epdf/10.10…#Alzheimersr#amyloidi#researchc#neurosciencec#proteinfoldingn#dementiaia

https://onlinelibrary.wiley.com/doi/epdf/10.10…

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Sheila Macrine, PhD @macrinephd.bsky.social · Sep 5

Nature's #biomimicry at its finest! rove beetle that grows a hyper-realistic "termite puppet" on its back to steal food 🐜 scim.ag/40kQtbI h/t @justinechterna9
#mimicry #evolution #entomology #newspecies #insects #natureiswild

Beetle grows ‘termite’ on back to steal food

Puppet helps insect trick real termites into feeding it

scim.ag

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Sheila Macrine, PhD @macrinephd.bsky.social · Sep 3

royalsocietypublishing.org/doi/10.1098/...

Evolution is coupled with branching across many granularities of life | Proceedings of the Royal Society B: Biological Sciences

Across many scales of life, the rate of evolutionary change is often accelerated at the time when one lineage splits into two. The emergence of novel protein function can be facilitated by gene duplication (neofunctionalization); rapid morphological ...

royalsocietypublishing.org

Sheila Macrine, PhD @macrinephd.bsky.social · Sep 3

royalsocietypublishing.org/doi/10.1098/...

Evolution is coupled with branching across many granularities of life | Proceedings of the Royal Society B: Biological Sciences

Across many scales of life, the rate of evolutionary change is often accelerated at the time when one lineage splits into two. The emergence of novel protein function can be facilitated by gene duplication (neofunctionalization); rapid morphological ...

royalsocietypublishing.org

Sheila Macrine, PhD @macrinephd.bsky.social · Sep 3

What is Life?" @drmichaellevin.bsky.social
& #TerrenceDeacon unite thermodynamics and cognition across all scales, bridging #EvoDev, #cogsci & #philosophy. Inspired by @danieldennett's legacy. youtu.be/HuWbHwPZd60?fe…#Evolutionon#Biologyg#Philosophyh#Consciousnesss#Complexityty

Terrence Deacon & Michael Levin: What is Life? Complexity, Cognition & the Origin of Purpose

YouTube video by Mind-Body Solution

https://youtu.be/HuWbHwPZd60?fe…

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Sheila Macrine, PhD @macrinephd.bsky.social · Sep 3

Can We Engineer Artificial Consciousness?" Professors Karl Friston & Mark Solms, pioneers in #neuroscience, #psychology, and theoretical #biology, dive into the frontiers of #consciousness @KarlFristonNews @Mark_Solms youtu.be/Jtp426wQ-JI?...

Karl Friston & Mark Solms: Is it Possible to Engineer Artificial Consciousness?

YouTube video by Mind-Body Solution

youtu.be

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Sheila Macrine, PhD @macrinephd.bsky.social · Sep 2

royalsocietypublishing.org/doi/10.1098/...

Evolution is coupled with branching across many granularities of life | Proceedings of the Royal Society B: Biological Sciences

Across many scales of life, the rate of evolutionary change is often accelerated at the time when one lineage splits into two. The emergence of novel protein function can be facilitated by gene duplic...

royalsocietypublishing.org

Sheila Macrine, PhD @macrinephd.bsky.social · Sep 2

royalsocietypublishing.org/doi/10.1098/...

Evolution is coupled with branching across many granularities of life | Proceedings of the Royal Society B: Biological Sciences

Across many scales of life, the rate of evolutionary change is often accelerated at the time when one lineage splits into two. The emergence of novel protein function can be facilitated by gene duplic...

royalsocietypublishing.org

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Sheila Macrine, PhD @macrinephd.bsky.social · Sep 2

Sorry the one on top of it works. But here you go. royalsocietypublishing.org/doi/10.1098/...

Evolution is coupled with branching across many granularities of life | Proceedings of the Royal Society B: Biological Sciences

Across many scales of life, the rate of evolutionary change is often accelerated at the time when one lineage splits into two. The emergence of novel protein function can be facilitated by gene duplic...

royalsocietypublishing.org

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Sheila Macrine, PhD @macrinephd.bsky.social · Sep 2

Which link? Air there are a few.

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Sheila Macrine, PhD @macrinephd.bsky.social · Aug 30

An updated evolutionary model shows that living systems evolve in a split-and-hit-the-gas dynamic, where new lineages appear in sudden bursts rather than during a long marathon of gradual changes. #Evolution #Biology #Adaptation www.quantamagazine.org/the-sudden-s...

The Sudden Surges That Forge Evolutionary Trees | Quanta Magazine

An updated evolutionary model shows that living systems evolve in a split-and-hit-the-gas dynamic, where new lineages appear in sudden bursts rather than during a long marathon of gradual changes.

www.quantamagazine.org

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Sheila Macrine, PhD @macrinephd.bsky.social · Aug 30

Open-source AI platform is democratizing the design of custom proteins! 🧬 It "reverse-engineers" the process, to create specific protein binders for therapeutic research applications. share.google/zQLs8VH9S7jm...
#OpenSource #AI #ProteinDesign #Biotechnology #ScienceForAll

An open-source AI platform to democratize protein design

Since its release last year, the open-source platform BindCraft, developed at EPFL, has already disrupted the world of protein design.

share.google

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Sheila Macrine, PhD @macrinephd.bsky.social · Aug 24

Why does AI get stuck in infinite loops?
"Unlike computers, we are beings in time-embodied, embedded, and entimed in our worlds. We can never be caught in infinite loops because we never exist out of time." bigthink.com/neuropsych/a...

Why AI gets stuck in infinite loops — but conscious minds don’t

Anil Seth suggests the difference is that living beings are rooted in time and entropy, a grounding that may be essential for consciousness.

bigthink.com

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Sheila Macrine, PhD @macrinephd.bsky.social · Aug 21

Cool interview with Karl Friston x.com/mlstreettalk...

x.com

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Sheila Macrine, PhD @macrinephd.bsky.social · Aug 21

New research shows a #BCI can decode a person's silent, inner speech into full sentences. Tapping into the brain's motor cortex, revolutionizing communication for those who cannot speak.
#Neuroscience #BrainComputerInterface #Neurotech #Accessibility
www.cell.com/cell/fulltex...

Inner speech in motor cortex and implications for speech neuroprostheses

Inner speech is robustly represented in the motor cortex and can be decoded in real time to restore communication to people with paralysis. Unintentional decoding of private inner speech can be preven...

www.cell.com

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Sheila Macrine, PhD @macrinephd.bsky.social · Aug 21

Can active inference model consciousness? New paper proposes it can, via a "Beautiful Loop Theory." It rests on three key conditions that create a self-evidencing system. 🧠 @KarlFristonNews
#Consciousness #ActiveInference ##FEP
www.sciencedirect.com/science/arti...

A beautiful loop: An active inference theory of consciousness

Can active inference model consciousness? We offer three conditions implying that it can. The first condition is the simulation of a world model, whic…

www.sciencedirect.com

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Sheila Macrine, PhD @macrinephd.bsky.social · Jul 23

Really intriguing talk coming up by @annaciaunica.bsky.social
on whether you need a body to be somebody, a self ?
FREE Online access Artificial General Intelligence (AGI25 ) Conference August 10-13 AGI sign up. agi-conf.org/2025/
Also a link to @AnnaCiaunica paper.
osf.io/preprints/psya…

OSF

https://osf.io/preprints/psya…

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Sheila Macrine, PhD @macrinephd.bsky.social · Jul 22

Just reposted. Let me know. I only post open access. So thanks for the heads up. I think it is so important to share science without journal paywalls.

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Sheila Macrine, PhD @macrinephd.bsky.social · Jul 22

Breakthrough! After 50 years, a monumental proof in abstract mathematics is bringing us closer to a Grand Unified Theory! This quiet revolution is one of science's biggest stories. #Mathematics #ScienceNews #GrandUnifiedTheory #AbstractMath
www.nature.com/articles/d41...

The breakthrough proof bringing mathematics closer to a grand unified theory

The Langlands programme has inspired and befuddled mathematicians for more than 50 years. A major advance has now opened up new worlds for them to explore.

www.nature.com

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Sheila Macrine, PhD @macrinephd.bsky.social · Jul 22

Hepatitis C found in the brain lining of individuals with schizophrenia and bipolar disorder suggesting link between HCV infection and these psychiatric conditions. hopkinsmedicine.org/news/newsroom/…#HepatitisCs#MentalHealtht#Schizophreniai#BipolarDisorderer

https://hopkinsmedicine.org/news/newsroom/…

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Sheila Macrine, PhD @macrinephd.bsky.social · Jul 22

Dive into the incredible world of Xenobots! 🐸 These living robots challenge our understanding of life, intelligence, consciousness. youtu.be/LTBZRVKUwyM?si… @drmichaellevin @Evan_mcg#Xenobotst#Bioengineeringn#AIA#Consciousnesss#Sciencece

Meet the Scientist Creating New Forms of Synthetic Life! Dr Michael Levin

YouTube video by Giant's Shoulder

https://youtu.be/LTBZRVKUwyM?si…

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Reposted by Sheila Macrine, PhD

DeBarra Shaw @d2chattoway.bsky.social · Jul 20

Exploring cognitive diversity. Timely and valuable reframing.

Sheila Macrine, PhD @macrinephd.bsky.social · Jul 15

How are animal minds shaped by evolution? 🧠 Explore cognitive diversity across the animal kingdom, moving beyond human-centric views. Reframes cognition as a set of diverse solutions to environmental challenges. #AnimalCognition #Evolution doi.org/10.1098/rstb...

Selection shapes diverse animal minds | Philosophical Transactions of the Royal Society B: Biological Sciences

This special issue explores the evolution of cognitive diversity across the animal kingdom, challenging the value of approaches that have a basis in human psychology in favour of a perspective that em...

doi.org

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