A fantastic collaboration with Dr. Christa Müller from the University of Bonn. Congratulations to graduate students Franka Westermann and Adam Oken for their efforts on this manuscript.
Our latest work on the human P2X2 receptor. We identified an alternate desensitized state conformation that provides insight into how ATP enters and/or leaves the pocket.
Another manuscript from our group this week with the first structures of the human P2X7 receptor facilitating development of a novel scaffold for P2X7R antagonists:
A fantastic collaboration with Dr. Christa Müller from the University of Bonn. Congratulations to graduate students Franka Westermann and Adam Oken for their efforts on this manuscript.
Our latest work on the human P2X2 receptor. We identified an alternate desensitized state conformation that provides insight into how ATP enters and/or leaves the pocket.
A fantastic collaboration with Dr. Christa Müller from the University of Bonn. Congratulations to graduate students Franka Westermann and Adam Oken for their efforts on this manuscript.
@volluminstitute.bsky.social neuroscientist Dr. Eric Gouaux has earned a rare distinction as a two-time recipient of the Javits Neuroscience Investigator Award from the National Institute of Neurological Disorders and Stroke! Read the full article: bit.ly/4b9gOw9
@ohsunews.bsky.social neuroscientist Dr. Eric Gouaux has earned a rare distinction as a two-time recipient of the Javits Neuroscience Investigator Award from the National Institute of Neurological Disorders and Stroke! news.ohsu.edu/2025/06/23/o...
A true Physician-Scientist and @OHSUSOM #MDPhD alum, Dr. Steve Mansoor, sharing details about how his lab uses #DrugDesign principles to fit the ligand into the target receptor like a jigsaw piece. 🧩Thank you for your presentation Dr. Mansoor! @OHSUNews @OHSUCardio @OHSUSOM
Navigating the worlds of research and patient care requires both precision and passion, and @ohsunews.bsky.social's Dr. Steven E. Mansoor finds fulfillment in this work as a physician-scientist. ohsufoundation.org/stories/the-...
Human P2X4 receptor gating is modulated by a stable cytoplasmic cap and a unique allosteric pocket. @ScienceAdvence. Check this #membrane #protein in the UniTmp database: https://pdbtm.unitmp.org/entry/9bqh
