Lightnews — Scholar-powered news

Guillaume Mas @masgu.bsky.social · Aug 11

I have also developed novel algorithms, using opencv, for the quantification of condensates properties in microscropy pictures. Check my github for more information! github.com/mas-gu/llps_...

github.com

1 3

Guillaume Mas @masgu.bsky.social · Aug 11

I have created the video showcasing the PDIA6 condensate dynamics and function using Blender and the Molecular Nodes module! Visualizing science like never before. #Blender #MolecularNodes @bradyajohnston.bsky.social

1 4

Guillaume Mas @masgu.bsky.social · Aug 11

Our results show PDIA6 condensates recruit key chaperones (BiP, ERdj3, Grp94) to enhance proinsulin folding & prevent misfolding, driven by Ca²⁺. This opens new perspectives for tackling protein misfolding diseases like diabetes! @natcellbio.nature.com

1 1

Guillaume Mas @masgu.bsky.social · Aug 11

Thrilled to share my first corresponding author paper as a project leader in @hillerlab.bsky.social ‪ Amazing work from first author @annaleder.bsky.social We discovered multi-chaperone condensates in the ER that revolutionise the current vision of protein folding!
www.nature.com/articles/s41...

1 8 19

Guillaume Mas @masgu.bsky.social · Jul 30

Shreyan Datta has demonstrated exceptional performance in our lab. I highly recommend him to anyone seeking an outstanding PhD candidate!

HillerLab @hillerlab.bsky.social · Jul 30

Last day for our summer student Shreyan Datta, who has done great work during his one and a half months in our lab working on the Hsp70 functional cycle! If you are looking for a PhD student in the next few months, Shreyan Datta will be a great fit for any lab!

Guillaume Mas @masgu.bsky.social · Jun 12

Great work from @annaleder.bsky.social in my chaperone sub-group at the Hiller Lab!

HillerLab @hillerlab.bsky.social · Jun 12

Congratulations to @annaleder.bsky.social receiving the Shepherd price for her PhD work at today’s @biozentrum.unibas.ch ‬ symposium @biozentrum-phd.bsky.social . Stay tuned for the official paper release in the coming weeks.

3

Reposted by Guillaume Mas

Magnetic Resonance News @nmr900.bsky.social · Jun 5

Two postdoctoral positions in the group of Dr. Malene R. Jensen at the Institute for Structural Biology in Grenoble, France, protein kinase (MAPK) cell signaling pathways (incl NMR, X-ray crystallography and cryo-electron microscopy) www.jensen-nmr.fr #NMRjobs #NMRchat #NMR 🧲

> Malene R. Jensen @ IBS Grenoble

Research team of CNRS research director Malene Ringkjøbing Jensen at the Institut de Biologie Structurale, Grenoble, France

www.jensen-nmr.fr

2 7

Guillaume Mas @masgu.bsky.social · Jun 5

Merci Mathieu!

1 1

Guillaume Mas @masgu.bsky.social · Jun 3

Thanks, glad you like it!

Guillaume Mas @masgu.bsky.social · Jun 2

It’s fully adaptable to study other nucleotide-driven machines, dissecting functional cycles, regulation, and cofactor effects with unprecedented resolution. #MolecularMachine

2

Guillaume Mas @masgu.bsky.social · Jun 2

Applied to the Hsp70 BiP NBD, in-cyclo NMR reveals all 11 microscopic kinetic rates of ATP binding, hydrolysis & product release — showing ADP·Pi release, not ATP hydrolysis, is the rate-limiting step controlling the cycle duration.

1 2

Guillaume Mas @masgu.bsky.social · Jun 2

Thrilled to share our new method in-cyclo NMR that lets us watch molecular machines in action — decoding molecular machine kinetics with atomic precision and exceptional time resolution in one go! 🚀 Check it out: doi.org/10.1038/s414... #NMR #StructuralBiology

4 5 23

Guillaume Mas @masgu.bsky.social · Apr 6

Great to be back at the @enc-conference.org #ENCISMAR2025 . Enjoying the conference and the beautiful wildlife.

4